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Specialty: Hematology
Source: Journal of Thrombosis and Haemostasis

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Total 139 results found since Jan 2013.

Associations of coagulation factors IX and XI levels with incident coronary heart disease and ischemic stroke: the REGARDS study
ConclusionsHigher FIX antigen was associated with incident CHD in blacks but not whites. FIX levels may increase CHD risk among blacks.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - April 10, 2017 Category: Hematology Authors: N.C. Olson, M. Cushman, S.E. Judd, B.M. Kissela, M.M. Safford, G. Howard, N.A. Zakai Tags: Original Article ‐ Coagulation Source Type: research

Circulating desphospho‐uncarboxylated matrix Gla protein and the risk of coronary heart disease and stroke
This study could not confirm that high dp‐ucMGP concentrations, reflecting a poor vitamin K status, are associated with increased CHD or stroke risk in the general population.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - April 1, 2014 Category: Hematology Authors: Geertje W. Dalmeijer, Yvonne T. Schouw, Elke J. Magdeleyns, Cees Vermeer, W.M. Monique Verschuren, Jolanda M.A. Boer, Joline W.J. Beulens Tags: Original Article ‐ Clinical Haemostasis and Thrombosis Source Type: research

Improving prediction of recanalization in acute large‐vessel occlusive stroke
ConclusionsAcute endovascular treatment is the single most important factor promoting recanalization in acute ischemic stroke. The presence of extracranial vessel stenosis or occlusion decreases recanalization rates. In patients with intracranial occlusions, higher NIHSS score and ASPECTS and normal vigilance facilitate recanalization. Clinical use of these predictors could influence recanalization strategies in individual patients.
Source: Journal of Thrombosis and Haemostasis - June 10, 2014 Category: Hematology Authors: P. Vanacker, D. Lambrou, A. Eskandari, P. Maeder, R. Meuli, G. Ntaios, P. Michel Tags: Original Article Source Type: research

Circulating desphospho‐uncarboxylated matrix γ‐carboxyglutamate protein and the risk of coronary heart disease and stroke
This study could not confirm that high dp‐ucMGP levels, reflecting poor vitamin K status, are associated with increased CHD or stroke risk in the general population.
Source: Journal of Thrombosis and Haemostasis - June 19, 2014 Category: Hematology Authors: G. W. Dalmeijer, Y. T. Schouw, E. J. Magdeleyns, C. Vermeer, W. M. M. Verschuren, J. M. A. Boer, J. W. J. Beulens Tags: Original Article Source Type: research

The C ‐reactive protein gene polymorphism predicts the risk of thromboembolic stroke in atrial fibrillation: a more than 10‐year prospective follow‐up study
ConclusionThe CRP gene triallelic polymorphism and the CRP level are associated with the risk of incident thromboembolic stroke in patients with AF.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - May 1, 2017 Category: Hematology Authors: Sheng ‐Nan Chang, Ling‐Ping Lai, Fu‐Tien Chiang, Jiunn‐Lee Lin, Juey‐Jen Hwang, Chia‐Ti Tsai Tags: Original Article ‐ Cardiovascular Medicine Source Type: research

The impact of atherosclerotic vascular disease in predicting stroke, thromboembolism and mortality in atrial fibrillation patients: A systematic review
ConclusionAtherosclerotic vascular disease (eg. peripheral arterial disease, complex aortic plaque and prior MI) are significant predictors of stroke, thromboembolism and mortality in subjects with AF.© 2013 International Society on Thrombosis and Haemostasis
Source: Journal of Thrombosis and Haemostasis - February 1, 2013 Category: Hematology Authors: Branavan Anandasundaram, Deirdre Lane, Stavros Apostolakis, Gregory Y H Lip Tags: Original Article ‐ Vascular Biology Source Type: research

The impact of atherosclerotic vascular disease in predicting a stroke, thromboembolism and mortality in atrial fibrillation patients: a systematic review
ConclusionAtherosclerotic vascular disease (e.g. peripheral arterial disease, complex aortic plaque and prior MI) are significant predictors of a stroke, thromboembolism and mortality in subjects with AF.
Source: Journal of Thrombosis and Haemostasis - May 15, 2013 Category: Hematology Authors: B. Anandasundaram, D. A. Lane, S. Apostolakis, G. Y. H. Lip Tags: Original Article Source Type: research

Coagulation factor XII genetic variation, ex vivo thrombin generation, and stroke risk in the elderly: results from the Cardiovascular Health Study
ConclusionsThese results support the importance of contact activation pathway‐dependent TG as a risk factor for ischemic stroke and indicate the importance of F12 SNPs on TG ex vivo and in vivo.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - August 1, 2015 Category: Hematology Authors: N. C. Olson, S. Butenas, L. A. Lange, E. M. Lange, M. Cushman, N. S. Jenny, J. Walston, J. C. Souto, J. M. Soria, G. Chauhan, S. Debette, W.T. Longstreth, S. Seshadri, A.P. Reiner, R. P. Tracy Tags: Original Article ‐ Coagulation Source Type: research

Coagulation factor XII genetic variation, ex vivo thrombin generation, and stroke risk in the elderly: results from the Cardiovascular Health Study
ConclusionsThese results support the importance of contact activation pathway‐dependent TG as a risk factor for ischemic stroke, and indicate the importance of F12 SNPs for TG ex vivo and in vivo.
Source: Journal of Thrombosis and Haemostasis - September 14, 2015 Category: Hematology Authors: N. C. Olson, S. Butenas, L. A. Lange, E. M. Lange, M. Cushman, N. S. Jenny, J. Walston, J. C. Souto, J. M. Soria, G. Chauhan, S. Debette, W. T. Longstreth, S. Seshadri, A. P. Reiner, R. P. Tracy Tags: Original Article Source Type: research

Munc13‐4 mediated secretion is essential for infarct progression but not intracranial haemostasis in acute stroke
This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - May 9, 2013 Category: Hematology Authors: David Stegner, Carsten Deppermann, Peter Kraft, Martina Morowski, Christoph Kleinschnitz, Guido Stoll, Bernhard Nieswandt Tags: Letter ‐ to the Editor Source Type: research

The prediction of postoperative stroke or death in patients with preoperative atrial fibrillation undergoing non‐cardiac surgery: a VISION sub‐study
ConclusionsIn AF patients, the 3 thromboembolic risk scores performed similarly to the RCRI in predicting death within 30 days and the CHADS2 score was the best predictor of postoperative stroke/death regardless of type of surgery.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - August 13, 2015 Category: Hematology Authors: Finlay A. McAlister, Michael Jacka, Michelle Graham, Erik Youngson, George Cembrowski, Sean M. Bagshaw, Neesh Pannu, Derek R. Townsend, Sadeesh Srinathan, Pablo Alonso‐Coello, P J Devereaux Tags: Original Article ‐ Cardiovascular Medicine Source Type: research

Improving Prediction of Recanalization in Acute Large Vessel Occlusive Stroke
ConclusionsAcute endovascular treatment is the single most important factor promoting recanalization in acute ischemic stroke. Presence of extracranial vessel stenosis or occlusion decreases recanalization rates. In patients with intracranial occlusions, higher NIHSS and ASPECTS and normal vigilance facilitate recanalization. Integration in treatment algorithms could influence recanalization strategies in individual patients.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - March 1, 2014 Category: Hematology Authors: Peter Vanacker, Dimitris Lambrou, Ashraf Eskandari, Philippe Maeder, Reto Meuli, George Ntaios, Patrik Michel Tags: Original Article ‐ Cardiovascular Medicine Source Type: research

Stroke in atrial fibrillation and improving the identification of ‘high risk’ patients: the crossroads of immunity and thrombosis
This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - August 25, 2015 Category: Hematology Authors: Eduard Shantsila, Gregory YH Lip Tags: Commentary Source Type: research

Optimising stroke prevention in elderly patients with atrial fibrillation
This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - August 24, 2016 Category: Hematology Authors: Gregory Y H Lip Tags: Commentary Source Type: research

Antigen levels of coagulation Factor XII, XI, prekallikrein and the risk of myocardial infarction and ischemic stroke in young women
ConclusionIncreased antigen levels of FXI were associated with an increase in ischemic stroke risk, whereas the risk of myocardial infarction is only marginally associated. FXII:ag and PK:ag levels were not substantially associated with MI and IS risk.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - February 21, 2014 Category: Hematology Authors: Bob Siegerink, Frits R Rosendaal, Ale Algra Tags: Original Article ‐ Cardiovascular Medicine Source Type: research