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Specialty: Nuclear Medicine

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Total 204 results found since Jan 2013.

Bioinks and in vitro neurovascular unit production - New prospects in Alzheimer's disease research.
Authors: Lougiaki P, Tsolaki M, Pantazaki A Abstract Neurovascular dysfunction is a central process in the pathogenesis of the stroke and most neurodegenerative diseases, including Alzheimer's disease. The multi-cell neurovascular unit (NVU) combines the components of the neural, vascular and extracellular matrix (ECM) into an important interface whose proper function is critical to maintaining brain health. Tissue engineering now offers new tools and information to promote understanding of NVU's operation. A promising area for the development of NVU models is their bio-production through 3D bio-printing to produce...
Source: Hellenic Journal of Nuclear Medicine - March 17, 2019 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

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Conclusions: Brown fat tissue is a normal variant in pediatric F-18 FDG studies. This diffuse activity can frustrate the radiologist reading the study and possibly cause a misdiagnosis. Propranolol may be a promising solution to reducing the brown fat in pediatric patients undergoing a F-18 FDG PET/CT scan. p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 16.0px Helvetica; -webkit-text-stroke: #000000} span.s1 {font-kerning: none} p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 16.0px Helvetica; -webkit-text-stroke: #000000} span.s1 {font-kerning: none}
Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Beaird, B. Tags: Technologist Student Papers II Source Type: research

Intrathecal injection of aptamer-conjugated DNA framework for the treatment of cerebral ischemia/reperfusion injury.
Conclusion: The high payload of an aptamer conjugated bipyramidal FNA was for cerebral IRI management was provided by intrathecal injection. This DNA framework alleviated the extent of cerebral IRI by acting as an antioxidant and inhibitor of inflammation.
Source: Journal of Nuclear Medicine - May 14, 2020 Category: Nuclear Medicine Authors: Rosenkrans, Z., Li, S., Jiang, D., Engle, J., Cai, W. Tags: Center for Molecular Imaging Innovation & amp; Translation (CMIIT) YIA Symposium Source Type: research

Novel methodolgy for measuring regional myocardial efficiency
Conclusions: Cardiac efficiency of specific tissue regions is obtained using a FE biomechanical model of the heart to calculate work and kinetic modelling of dynamic 11C-acetate data to calculate oxygen consumption. The calculation of myocardial efficiency in patients provides a wealth of diagnostic information of functional analysis as well as biochemical and physiological characterization of inhomogeneity of cardiac efficiency.
Source: Journal of Nuclear Medicine - May 14, 2020 Category: Nuclear Medicine Authors: Gullberg, G., Shrestha, U., Veress, A., Segars, W. P., Liu, J., Ordovas, K., Seo, Y. Tags: New Techniques and Tracers for Ischemic Heart Disease (Basic Science, Cardio) Source Type: research

Risk Prediction of Coronary Flow Reserve is Strongly Influenced by the Burden of Coronary Calcification
Conclusions: Coronary flow reserve helps to risk stratify patients with CAC &gt 10. These findings have significant clinical implications but will need confirmation in larger studies.
Source: Journal of Nuclear Medicine - May 14, 2020 Category: Nuclear Medicine Authors: Khan, M., Bravo, P., Vidula, M., Selvaraj, S., De Feria Alsina, A. E., Wiener, P., Szapary, H., Julien, H., Litt, H., Pryma, D., Dubroff, J., Guerraty, M. Tags: Technical Considerations and Clinical Application of Absolute Myocardial Blood Flow Source Type: research

Correlation of Global Cardiac Microcalcification with CHADS2and CHADS2-VASc Scores in Individuals At-risk for Cardiovascular Disease as Assessed by NaF-PET/CT
Conclusions: Global cardiac NaF uptake on PET/CT correlated positively with both CHADS2 and CHA2DS2-VASc scores. Our data provides further evidence to support the association of these scoring systems with cardiac atherosclerotic burden.
Source: Journal of Nuclear Medicine - May 14, 2020 Category: Nuclear Medicine Authors: Rojulpote, C., Patil, S., Gonuguntla, K., Revheim, M.-E., Zirakchian Zadeh, M., Werner, T., Gerke, O., Hoilund-Carlsen, P. F., Alavi, A. Tags: Clinical Science (Poster Session) Source Type: research

Preliminary study about the relationship between degree of internal carotid artery stenosis, wall shear stress on MR angiography and 18F-FDG uptake on PET/CT
Conclusions: These preliminary results indicated that there were significant correlations between degree of internal carotid artery stenosis, WSS and 18F-FDG uptake in patients with carotid artery stenosis. Furthermore, the relationship between WSS and 18F-FDG uptake was higher than that between degree of internal carotid artery stenosis and 18F-FDG uptake.
Source: Journal of Nuclear Medicine - May 14, 2020 Category: Nuclear Medicine Authors: Takami, Y., Norikane, T., Yamamoto, Y., Fujimoto, K., Mitamura, K., Nishiyama, Y. Tags: Clinical Science (Poster Session) Source Type: research

Conventional and molecular imaging in sickle cell disease
Conclusions: Central nervous system: About 25% of SCD patients are affected by vascular involvement of central nervous system. CT scan has been used to detect cerebral infarction. Subclinical cranial MRI lesions yield important predictive values as a risk factor of stroke, even when detected in asymptomatic patients. SPECT is a useful technique for early detection of deficits in cerebral perfusion in patients with SCD. Decreases in cerebral perfusions may lead to silent infarction, stroke, or neurocognitive diseases. PET may improve sensitivity in detection of impaired metabolism in the area surrounding a major vessel infa...
Source: Journal of Nuclear Medicine - May 18, 2021 Category: Nuclear Medicine Authors: Taghvaei, R., Sirous, R., Raynor, W., Amanullah, A., Werner, T., Revheim, M.-E., Hoilund-Carlsen, P. F., Alavi, A. Tags: General Clinical Specialties Source Type: research

PET/MRI Assessment of Acute Cardiac Inflammation 1 Month After Left-Sided Breast Cancer Radiation Therapy
Conclusion: Myocardial 18F-FDG uptake and functional MRI, including stroke volume and ECVs, were sensitive to changes at 1 mo after breast cancer RT, with findings suggesting an acute cardiac inflammatory response to RT.PMID:37192822 | DOI:10.2967/jnmt.122.264960
Source: Journal of Nuclear Medicine Technology - May 16, 2023 Category: Nuclear Medicine Authors: Oi Wai Chau Ali Islam Michael Lock Edward Yu Robert Dinniwell Brian Yaremko Muriel Brackstone William Pavlosky John Butler Heather Biernaski Chantelle Graf Gerald Wisenberg Frank S Prato Stewart Gaede Source Type: research