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Specialty: Nuclear Medicine
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Total 204 results found since Jan 2013.
Case report of nuclear medicine, bone scan imaging on a patient with heat stroke induced rhabdomyolysis
J Nucl Med Technol. 2021 Jul 30:jnmt.121.262501. doi: 10.2967/jnmt.121.262501. Online ahead of print.ABSTRACTBone scan continues to be the second greatest-volume nuclear imaging procedure, offering the advantage of total body examination, low cost, and high sensitivity not only for metastatic lesions but also benign conditions. Its power rests in the physiological uptake and pathophysiologic behavior of 99m technetium (99m-Tc) diphosphonates. 1 The localization of radiotracers in damaged skeletal muscles is because calcium builds up in them and provides a site for radiotracer deposition when combined with phosphate.1 In ca...
Source: Journal of Nuclear Medicine Technology - July 31, 2021 Category: Nuclear Medicine Authors: Jitesh Dhingra Yoram Baum Source Type: research
A Longitudinal PET/MRI Study of Colony-Stimulating Factor 1 Receptor-Mediated Microglia Depletion in Experimental Stroke
Conclusion: Longitudinal TSPO PET/MRI allows the assessment of target engagement and optimization of drug efficiency. PLX5622 has promising immunomodulatory effects, and the optimal therapeutic time window for its application needs to be defined.
Source: Journal of Nuclear Medicine - March 1, 2022 Category: Nuclear Medicine Authors: Barca, C., Kiliaan, A. J., Foray, C., Wachsmuth, L., Hermann, S., Faber, C., Schafers, M., Wiesmann, M., Jacobs, A. H., Zinnhardt, B. Tags: Featured Basic Science Article Source Type: research
Short-Term Colony-Stimulating Factor 1 Receptor Inhibition-Induced Repopulation After Stroke Assessed by Longitudinal 18F-DPA-714 PET Imaging
Conclusion: This study highlighted the potential of 18F-DPA-714 PET/CT imaging to track microglia and macrophage repopulation after short-term CSF-1R inhibition in stroke.
Source: Journal of Nuclear Medicine - September 1, 2022 Category: Nuclear Medicine Authors: Barca, C., Kiliaan, A. J., Wachsmuth, L., Foray, C., Hermann, S., Faber, C., Schafers, M., Wiesmann, M., Zinnhardt, B., Jacobs, A. H. Tags: Basic Science Investigations Source Type: research
Time sequential monitoring of the translocator protein 18 kDa (TSPO) and acetylcholinesterase (AChE) expression in a middle cerebral artery occlusion (MCAO) rat model using PET radiotracers
Conclusions Our results indicate that an AChE level elevate in the early course of disease and becomes normal, while TSPO expression elevates later, and is sustained throughout the post-ischemic injury. It is known that different inflammatory mechanisms are involved according to the time window after stroke 4. AChE was reported to be related with early apoptosis after stroke. TSPO related cytokines such as TNF-α and IL-6 increased later. Our study shows that the brain inflammatory process can be demonstrated and quantified with PET imaging. RESEARCH SUPPORT: .
Source: Journal of Nuclear Medicine - May 23, 2016 Category: Nuclear Medicine Authors: Song, Y. S., Moon, B. S., Chung, Y. A., Lee, B. C., Kim, S. E. Tags: MTA I: Educational Exhibits Posters Source Type: research
