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Modafinil for the Improvement of Patient Outcomes Following Traumatic Brain Injury
Conclusion. Modafinil is a central nervous system stimulant with well-established effectiveness in the treatment of narcolepsy and shift-work sleep disorder. There is conflicting evidence about the benefits of modafinil in the treatment of fatigue and EDS secondary to TBI. One randomized, controlled study states that modafinil does not significantly improve patient wakefulness, while another concludes that modafinil corrects EDS but not fatigue. An observational study provides evidence that modafinil increases alertness in fatigued patients with past medical history of brainstem diencephalic stroke or multiple sclerosis. ...
Source: Innovations in Clinical Neuroscience - April 1, 2018 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Review excessive daytime sleep fatigue head injury modafinil stroke TBI traumatic brain injury Source Type: research

Contemporary Antiplatelet and Anticoagulant Therapies for Secondary Stroke Prevention: A Narrative Review of Current Literature and Guidelines
AbstractPurpose of ReviewStroke is a leading cause of death and disability worldwide. The annual incidence of new or recurrent stroke is approximately 795,000 cases per year in the United States, of which 87% are ischemic in nature. In addition to the management of modifiable high-risk factors to reduce the risk of recurrent stroke, antithrombotic agents (antiplatelets and anticoagulants) play an important role in secondary stroke prevention. This review will discuss the published literature on the use of antiplatelets and anticoagulants in secondary prevention of acute ischemic stroke and transient ischemic attack (TIA), ...
Source: Current Neurology and Neuroscience Reports - April 11, 2023 Category: Neuroscience Source Type: research

Timeliness of Nursing Care Delivered by Stroke Certified Registered Nurses as Compared to Non–Stroke Certified Registered Nurses to Hyperacute Stroke Patients
In this retrospective, nonexperimental, comparative descriptive design using convenience sampling, the timeliness of care delivered by 11 Stroke Certified Registered Nurses (SCRNs) to 95 hyperacute stroke patients (last known well of 4.5 hours or less) on the acute stroke protocol set by Target: Stroke Phase II Campaign Manual was compared with that of 13 non-SCRNs in a small, rural, level III stroke facility in the southwestern region of the United States. There was statistical significance in the total timeliness of care delivered by SCRNs to hyperacute stroke patients as compared with the non-SCRNs (t = −4.109, P = .0...
Source: Journal of Neuroscience Nursing - January 8, 2019 Category: Neuroscience Tags: Article Source Type: research

Stroke-Specific Refinements to Naylor's Transitional Care Model to Address the Storm of Uncertainty and Unmet Survivor and Caregiver Needs
CONCLUSION: Unmet needs identified by SSs and CGs were used to extend NTCM specific to the stroke population and to develop the Recommendations and Exemplars for Stroke Specific Comprehensive Transitional Care Delivery (see Supplementary Digital Content, available at http://links.lww.com/JNN/A385). Researchers and practitioners can use the findings to develop and deliver more comprehensive TC to SSs and CGs.
Source: Journal of Neuroscience Nursing - January 15, 2022 Category: Neuroscience Tags: Articles Source Type: research

Impact of a Structured Response and Evidence-Based Checklist on In-hospital Stroke Outcomes
CONCLUSIONS Use of a checklist during inpatient stroke events can potentially increase adherence to guidelines for appropriate treatment and reduce mortality. Hospital response teams should consider use of a structured response system with an evidence-based checklist for high-acuity, low-frequency events such as in-hospital stroke.
Source: Journal of Neuroscience Nursing - April 29, 2020 Category: Neuroscience Tags: Article Source Type: research

Back to Basics: Adherence With Guidelines for Glucose and Temperature Control in an American Comprehensive Stroke Center Sample
Conclusion: Glucose and temperature control may be overlooked in this era of rapid stroke diagnosis and treatment. Acute stroke nurses are well positioned to assume leadership of glucose and temperature monitoring and treatment.
Source: Journal of Neuroscience Nursing - May 5, 2018 Category: Neuroscience Tags: Article Source Type: research

Scientific Landscape of Oxidative Stress in Stroke: From a Bibliometric Analysis to an in-Depth Review
Neurochem Res. 2023 Jul 28. doi: 10.1007/s11064-023-03999-5. Online ahead of print.ABSTRACTStroke is an acute cerebrovascular disease resulting from either obstruction or rupture of a blood vessel in the brain. Oxidative stress (OS), referred to a status where cellular oxidative capacities overwhelm antioxidative defenses, is involved in the pathophysiology of stroke. The bibliometric analysis and in-depth review aim to depict the research trend of OS in stroke. Relevant scientific publications were acquired from the Web of Science Core Collection database. Scientific landscape of OS in stroke was illustrated by general qu...
Source: Neurochemical Research - July 28, 2023 Category: Neuroscience Authors: Minqi Zhou Jiayu Xin Jinyu Chen Caiyun Sun Bingyue Huo Wenting Zhang Xiangqian Liu Source Type: research

A Pilot Primary Stroke Prevention Program for Elderly Korean Americans
Conclusion: This study demonstrated feasibility and effectiveness of the program to improve stroke knowledge and healthy behaviors in elderly Korean Americans.
Source: Journal of Neuroscience Nursing - November 13, 2018 Category: Neuroscience Tags: Article Source Type: research

The 100 most-cited articles about the role of neurovascular unit in stroke 2001-2020: A bibliometric analysis
CONCLUSION: There has been growing attention and efforts made in the field of stroke and NVU. The merit of the above findings may help to shape the research policy in ischemic stroke both at the country and institutional level.PMID:33764687 | DOI:10.1111/cns.13636
Source: CNS Neuroscience and Therapeutics - March 25, 2021 Category: Neuroscience Authors: Lv Xie Bingwei Lu Yezhi Ma Jiemin Yin Xiaozhu Zhai Chen Chen Wanqing Xie Yueman Zhang Li Zheng Peiying Li Source Type: research

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