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The 100 most-cited articles about the role of neurovascular unit in stroke 2001-2020: A bibliometric analysis
CONCLUSION: There has been growing attention and efforts made in the field of stroke and NVU. The merit of the above findings may help to shape the research policy in ischemic stroke both at the country and institutional level.PMID:33764687 | DOI:10.1111/cns.13636
Source: CNS Neuroscience and Therapeutics - March 25, 2021 Category: Neuroscience Authors: Lv Xie Bingwei Lu Yezhi Ma Jiemin Yin Xiaozhu Zhai Chen Chen Wanqing Xie Yueman Zhang Li Zheng Peiying Li Source Type: research

Don't brush off early warning signs of a stroke
It's important to recognize the signs of a stroke and get to a hospital fast. Time is brain: the longer the gap between the start of stroke symptoms and treatment, the more brain cells die, reports the December 2013 issue of the Harvard Men's Health Watch. Experts have developed the FAST (Face, Arms, Speech, Time) mnemonic device to highlight some of the more obvious signs of a brain attack. A more detailed list includes: Face drooping. One side of the face goes slack. A smile appears uneven. One arm is weak. When raising both arms, one arm drifts downward. Numbness. Loss of feeling on one side of the body, or one part of...
Source: New Harvard Health Information - November 30, 2013 Category: Consumer Health News Source Type: news

Factor VIII as a Predictor of Stroke Etiology (P1.115)
CONCLUSIONS:Cohort characteristics differed significantly by pFVIII levels. Mean pFVIII level differed across TOAST etiologies, with "Other" etiology strokes consistently reporting elevated pFVIII levels, significantly different from reference. Our analysis suggests that pFVIII potentially serves as a novel clinical characteristic for appropriately classifying TOAST subgroups, which thereby may potentially inform appropriate secondary stroke prevention.Disclosure: Dr. Halstead has nothing to disclose. Dr. Yeh has nothing to disclose. Dr. Schluter has nothing to disclose. Dr. Monlezun, Jr has nothing to disclose. Dr. George...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Halstead, M., Yeh, A., Schluter, L., Monlezun, D., George, A., Schild, C., El Khoury, R., Martin-Schild, S. Tags: Cerebrovascular Disease and Interventional Neurology: Antiplatelet Agents and Miscellaneous Source Type: research

Johnson & Johnson Launches Heartline ™, the First-of-its-Kind, Virtual Study Designed to Explore if a New iPhone App and Apple Watch Can Help Reduce the Risk of Stroke
New Brunswick, NJ, February 25, 2020 — Johnson & Johnson (NYSE: JNJ) today announced that the Janssen Pharmaceutical Companies of Johnson & Johnson, in collaboration with Apple, opened enrollment for the Heartline™ Study. The study is designed to explore if the Heartline™ Study app on iPhone and heart health features on Apple Watch can improve health outcomes, including reducing the risk of stroke, with earlier detection of atrial fibrillation (AFib). AFib, a common form of irregular heart rhythm, is a leading cause of stroke in the U.S. To enroll in the Heartline™ Study, individuals must be age 65 or older...
Source: Johnson and Johnson - February 25, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Global trends in perioperative stroke research from 2003 to 2022: a web of science-based bibliometric and visual analysis
ConclusionPublications regarding perioperative stroke have experienced rapid growth in the past 20 years and are likely to continuously increase. Research on perioperative antiplatelet and antithrombotic, cardiovascular surgery, postoperative cognitive dysfunction, thrombectomy, tranexamic acid, and frozen elephant trunk has attracted increasing attention, and these topics are emerging hotspots of present research and possible candidates for future research.
Source: Frontiers in Neurology - May 31, 2023 Category: Neurology Source Type: research

Twin surgeries bring this family a stroke of luck
Ryan Earle is outgoing and upbeat, goofing around in his neurosurgeon’s office. He’s had two strokes, but he’s recovering steadily, a testament to the resilience of children’s brains. His twin brother Tyler, with him at the visit, has avoided a likely stroke altogether. Both Ryan and Tyler, 8, have a rare brain disorder called moyamoya disease, in which the internal carotid arteries become narrowed, slowing the flow of blood to their brains. Without surgery, moyamoya poses a five-year stroke risk of 60 to 90 percent. The boys’ moyamoya symptoms were subtle: “They would have a mild headache, then they’d throw ...
Source: Thrive, Children's Hospital Boston - December 29, 2014 Category: Pediatrics Authors: Lisa Fratt Source Type: news

Combination of a cholesterol-lowering statin and ezetimibe lowers risk of a heart attack or stroke
High cholesterol is a key culprit in the development of cardiovascular disease, the leading cause of death in the United States and many other developed countries. We know that lowering cholesterol helps prevent heart attacks and strokes. But an unanswered question remains: how low should you go? New research published online today in The New England Journal of Medicine suggests that lower is better. Cholesterol and cardiovascular disease Cholesterol travels through the bloodstream in two main particles: high-density lipoprotein (HDL) and low-density lipoprotein (LDL). HDL scavenges cholesterol from the bloodstream and fro...
Source: New Harvard Health Information - June 4, 2015 Category: Consumer Health News Authors: Gregory Curfman, MD Tags: Drugs and Supplements Heart Health cholesterol ezetimibe Source Type: news

Stroke Rehab Technology Aims To Speed Healing
Watching someone who has suffered a stroke try to perform everyday actions such as walking down the sidewalk or even bringing a cup to their lips can serve as a sobering reminder of how fragile full and robust health is, and also serves as an inspiration for those dedicated to improving the lives of those patients. Steven Plymale, recently named CEO of Toronto-based MyndTec, said his reaction to watching videos of patients using the company's MyndMove functional electrical stimulation (FES) rehabilitation system was one of the reasons he joined MyndTec. "They are very compelling," Plymale said of the demonstration videos,...
Source: MDDI - November 22, 2017 Category: Medical Devices Authors: Greg Goth Tags: Electronics Source Type: news

Long-term effects of contralesional rTMS in severe stroke: Safety, cortical excitability, and relationship with transcallosal motor fibers
CONCLUSIONS: Our results suggest that noninvasive neuromodulation of the contralesional hemisphere may present a possibility to assist adaptive neuroplastic changes in severe chronic stroke. Implementation of DTI-derived measures of transcallosal microstructural integrity may allow for individually-tailored interventions to guide processes of interhemispheric neuroplasticity. Further research is warranted to establish the clinical value of these findings in neurorehabilitation settings for subjects with chronic severe stroke. Content Type Journal ArticlePages -DOI 10.3233/NRE-141191Authors Asli Demirtas-Tatlidede, Beren...
Source: NeuroRehabilitation - December 29, 2014 Category: Rehabilitation Tags: NeuroRehabilitation Source Type: research

Reversing the effects of the new anti-clotting drugs
The oral anticoagulant warfarin (Coumadin) became available for prescription in 1954. This anti-clotting drug commanded national attention when President Dwight Eisenhower received the drug as part of his treatment following a heart attack. No other oral anticoagulant was successfully developed and marketed in the United States until 2010. Warfarin is a dangerous drug. Along with insulin, it is responsible for the most emergency hospitalizations due to adverse drug reactions. Whereas insulin causes low blood sugar, warfarin is notorious for the complication of major bleeding. Warfarin is plagued by hundreds of drug-drug an...
Source: New Harvard Health Information - December 9, 2015 Category: Consumer Health News Authors: Samuel Z. Goldhaber, MD Tags: Drugs and Supplements Health Heart Health Hypertension and Stroke anti-clotting coumadin deep-vein-thrombosis DVT Source Type: news

Only the overworked die young
Follow me at @JohnRossMD Billy Joel was on to something. As the singer-songwriter suggested in “Movin’ Out,” working too hard really can give you a “heart attack-ack-ack…” And, as a recent study has also shown, stroke may be an even bigger problem than heart attack in people who are overworked. For the study, researchers from University College London compiled data on the relationship between working hours and heart attack risk in over 600,000 workers, as well as similar data on stroke risk in over 500,000 workers. They adjusted their data to compensate for individual workers’ differences due to healt...
Source: New Harvard Health Information - December 14, 2015 Category: Consumer Health News Authors: John Ross, MD, FIDSA Tags: Behavioral Health Heart Health Hypertension and Stroke Prevention Stress overworked Source Type: news