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Total 1650 results found since Jan 2013.

The efficacy and safety of Jin's three-needle therapy vs. placebo acupuncture on anxiety symptoms in patients with post-stroke anxiety: A study protocol for a randomized controlled trial
This study firstly verifies the real effectiveness of JTNT. Besides, the changes in serum indexes on the hypothalamic-pituitary-adrenal axis (HPA axis) are observed dynamically by the Enzyme-Linked ImmunoSorbent Assay (ELISA). The activation of different brain regions by JTNT is recorded using resting functional magnetic resonance imaging (rs-fMRI). Therefore, we can provide more practical and powerful evidence-based medical evidence for clinical decisions.MethodThis is a 16 week parallel, single-blind, random, controlled trial, including baseline, 4 weeks of treatment, and 12 weeks of follow-up. A total of 114 participant...
Source: Frontiers in Psychiatry - September 7, 2022 Category: Psychiatry Source Type: research

Blood pressure variability and early neurological deterioration according to the chronic kidney disease risk categories in minor ischemic stroke patients
by Jae-Chan Ryu, Jae-Han Bae, Sang Hee Ha, Jun Young Chang, Dong-Wha Kang, Sun U. Kwon, Jong S. Kim, Chung Hee Baek, Bum Joon Kim ObjectiveChronic kidney disease (CKD) increases blood pressure variability (BPV) and affects stroke outcomes. However, the effect of BPV on early neurological deterioration (END) may be different according to the renal function. MethodsWe enrolled ischemic stroke patients with a National Institutes of Health Stroke Scale of ≤5. END was defined as worsening of ≥1 point in motor power or ≥2 points in total score. BPV was calculated with BP measured during the first 5 days and presented as st...
Source: PLoS One - September 7, 2022 Category: Biomedical Science Authors: Jae-Chan Ryu Source Type: research

Clinical effect of successful reperfusion in patients presenting with NIHSS < 6 and large vessel occlusion
Endovascular thrombectomy is now recommended as the standard treatment for acute ischemic stroke (AIS) with proximal large  vessel occlusion (LVO) of the anterior circulation with National Institutes of Health Stroke Scale (NIHSS) ≥6.1 The Safe Implementation of Thrombolysis in Stroke (SITS) International Stroke Thrombolysis registry reviewed vessel imaging and reported that 25% of patients with mild stroke had extr acranial or intracranial occlusion.2 The efficacy of endovascular thrombectomy (EVT) in patients with a low NIHSS with the presence of AIS-LVO continues to be hotly debated, including retrospective and pros...
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2022 Category: Neurology Authors: Yang Hu, Shuhan Huang, Gongbo Li, Min Song, Yuqing Zhang, Dongmei Wu, Yangmei Chen, Meng Zhang, Haiyan Luo Source Type: research

P74 Keep it simple: MAC (Manual Aspiration with Contrast) technique for the endovascular management of acute ischemic stroke (LVO & MVO)
We report a prospectively collected clinical experience with a simple technique: MAC (Manual Aspiration Contrast Enhancement) as the primary method for vessel recanalization.Gently contrast injection while the aspiration catheter is advancedto the thrombus and subsequentlycreating a closed-loop system with the contrast column within the cathetercan result in better visualization during the aspiration, thus improving the FPEavoiding clot fragmentation, multiple passes and blind movements of catheter by a single operator.Methods47 prospectively patients with ELVO and 3 cases of middle vessel occlusion (MVO) at four instituti...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Pabon, B., Torres, V., Patino, M., Pelaez, F., Mutis, J. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

Trial of a prehospital intervention with traditional Chinese medicine for acute stroke (TRACE): Protocol for a mixed-methods research study
Discussion: The results of the TRACE study will provide preliminary evidence for the relationship between XNJI used within 24 h of onset and the presence of END on the third day after stroke onset; it will aid in improving the current knowledge regarding the early use of XNJI for stroke first aid.Clinical Trial Registration:clinicaltrials.gov, identifier NCT04275349
Source: Frontiers in Pharmacology - August 29, 2022 Category: Drugs & Pharmacology Source Type: research

Risk of Subsequent Events in Patients With Minor Ischemic Stroke or High-Risk Transient Ischemic Attack
This study aimed to present the prognosis after minor acute ischemic stroke (AIS) or transient ischemic attack (TIA), using a definition of subsequent stroke in accordance with recent clinical trials. In total, 9,506 patients with minor AIS (National Institutes of Health Stroke Scale ≤ 5) or high-risk TIA (acute lesions or ≥ 50% cerebral artery steno-occlusion) admitted between November 2010 and October 2013 were included. The primary outcome was the composite of stroke (progression of initial event or a subsequent event) and all-cause mortality. The cumulative incidence of stroke or death was 11.2% at 1 month, 13.3% a...
Source: Atherosclerosis - August 23, 2022 Category: Cardiology Authors: Keon-Joo Lee Dong Woo Shin Hong-Kyun Park Beom Joon Kim Jong-Moo Park Kyusik Kang Tai Hwan Park Kyung Bok Lee Keun-Sik Hong Yong-Jin Cho Dong-Eog Kim Wi-Sun Ryu Byung-Chul Lee Kyung-Ho Yu Mi-Sun Oh Soo Joo Lee Jae Guk Kim Jun Lee Jae-Kwan Cha Dae-Hyun Kim Source Type: research