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Total 678 results found since Jan 2013.

Effect of mitral regurgitation on stroke risk in patients with non-rheumatic atrial fibrillation
CONCLUSION: In our large registry of patients with non-rheumatic AF, we did not find a protective effect of grade 3-4 MR on the risk of stroke.PMID:36030169 | DOI:10.1016/j.acvd.2022.05.006
Source: Archives of Cardiovascular Diseases - August 27, 2022 Category: Cardiology Authors: Sergio Raposeiras-Roub ín Pablo Dom ínguez-Erquicia Emad Abu-Assi Ana Ledo-Pi ñeiro Andr é González-García Carla Iglesias-Otero Enrique Garc ía-Campo Andr és Íñiguez-Romo Source Type: research

Translation into Spanish and a preliminary analysis of the psychometric properties of the Newcastle Stroke-Specific Quality of Life Measure (NEWSQOL) questionnaire for rating the quality of life among post-stroke patients.
CONCLUSION: The Spanish version of the NEWSQOL questionnaire is reliable for evaluating the quality of life in post-stroke patients, as well as being well accepted. The questionnaire must be used in more broader samples in order to evaluate its validity and sensitivity. PMID: 29178105 [PubMed - in process]
Source: Revista de Neurologia - November 29, 2017 Category: Neurology Authors: Soto-Vidal C, Pacheco-da-Costa S, Fernandez-Guinea S, Gallego-Izquierdo T Tags: Rev Neurol Source Type: research

Performance of the RACE Score for the Prehospital Identification of Large Vessel Occlusion Stroke in a Suburban/Rural EMS Service.
CONCLUSION: The RACE scale demonstrated acceptable discrimination, yet the sensitivity and positive predictive value were lower in this cohort of EMS professionals in the U.S. than in the original validation study conducted in Spain. Further work is needed to determine the optimal prehospital screening tool for identification of LVO. PMID: 30668202 [PubMed - as supplied by publisher]
Source: Prehospital Emergency Care - January 23, 2019 Category: Endocrinology Tags: Prehosp Emerg Care Source Type: research

Differential Characteristics of Ischemic and Hemorrhagic Stroke in Patients with Cerebral Small Vessel Disease
Conclusion: Identification of differential clinical and prognostic profile between ischemic and hemorrhagic consequences of underlying cerebral SVD is useful for risk stratification in the current process pursuing precision medicine.
Source: Neurology India - February 24, 2021 Category: Neurology Authors: Mireia Bernal Paula Escarcena Adri & #224; Arboix Lluis Garcia-Eroles Enric Verg & #233;s Laura D & #237;ez Joan Massons Source Type: research

DNA methylation analyses identify an intronic < i > ZDHHC6 < /i > locus associated with time to recurrent stroke in the Vitamin Intervention for Stroke Prevention (VISP) clinical trial
by Nicole M. Davis Armstrong, Wei-Min Chen, Fang-Chi Hsu, Michael S. Brewer, Natalia Cullell, Israel Fern ández-Cadenas, Stephen R. Williams, Michèle M. Sale, Bradford B. Worrall, Keith L. Keene Aberrant DNA methylation profiles have been implicated in numerous cardiovascular diseases; however, few studies have investigated how these epigenetic modifications contribute to stroke recurrence. The aim of this study was to identify methylation loci associated with the time to recurrent cerebr o- and cardiovascular events in individuals of European and African descent. DNA methylation profiles were generated for 180 individu...
Source: PLoS One - July 12, 2021 Category: Biomedical Science Authors: Nicole M. Davis Armstrong Source Type: research

Allogeneic adipose tissue-derived mesenchymal stem cells in ischaemic stroke (AMASCIS-02): a phase IIb, multicentre, double-blind, placebo-controlled clinical trial protocol
Introduction Stroke is a serious public health problem, given it is a major cause of disability worldwide despite the spread of recanalisation therapies. Enhancement of brain plasticity with stem cell administration is a promising innovative therapy to reduce sequelae in these patients. Methods and analysis We have developed a phase IIb, multicentre, randomised, double-blind, placebo-controlled clinical trial protocol to evaluate the safety and efficacy of intravenous administration of allogeneic adipose tissue-derived mesenchymal stem cells (AD-MSCs) in patients with acute ischaemic stroke, concurrently with conventional...
Source: BMJ Open - August 9, 2021 Category: General Medicine Authors: de Celis-Ruiz, E., Fuentes, B., Moniche, F., Montaner, J., Borobia, A. M., Gutierrez-Fernandez, M., Diez-Tejedor, E. Tags: Open access, Neurology Source Type: research

The economic burden of stroke: a systematic review of cost of illness studies
J Med Life. 2021 Sep-Oct;14(5):606-619. doi: 10.25122/jml-2021-0361.ABSTRACTStroke is one of the leading causes of morbidity and mortality worldwide. As the number of stroke cases is rising from one year to another, policymakers require data on the amount spent on stroke to enforce better financing policies for prevention, hospital care, outpatient rehabilitation services and social services. We aimed to systematically assess the economic burden of stroke at global level. Cost of stroke studies were retrieved from five databases. We retrieved the average cost per patient, where specified, or estimated it using a top-down a...
Source: Journal of Medicine and Life - January 14, 2022 Category: General Medicine Authors: Stefan Strilciuc Diana Alecsandra Grad Constantin Radu Diana Chira Adina Stan Marius Ungureanu Adrian Gheorghe Fior-Dafin Muresanu Source Type: research