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Total 7216 results found since Jan 2013.
Social Determinants of Health and Racial Disparities in Cardiac Events in Breast Cancer
CONCLUSIONS: Neighborhood and built environment variables are the most important SDOH predictors for 2-year MACE, and NHB patients were more likely to have unfavorable SDOH conditions. This finding reinforces that race is a social construct.PMID:37433439 | DOI:10.6004/jnccn.2023.7023
Source: Journal of the National Comprehensive Cancer Network : JNCCN - July 11, 2023 Category: Cancer & Oncology Authors: Nickolas Stabellini Mantas Dmukauskas Marcio S Bittencourt Jennifer Cullen Amie J Barda Justin X Moore Susan Dent Husam Abdel-Qadir Aniket A Kawatkar Ambarish Pandey John Shanahan Jill S Barnholtz-Sloan Kristin A Waite Alberto J Montero Avirup Guha Source Type: research
Chlorthalidone versus hydrochlorothiazide for preventing cardiovascular disease in hypertension: Is the case closed?
Hellenic J Cardiol. 2023 Jul 8:S1109-9666(23)00115-X. doi: 10.1016/j.hjc.2023.07.003. Online ahead of print.ABSTRACTThe optimal diuretic choice [hydrochlorothiazide (HCTZ) or chlorthalidone (CTD)] for the management of hypertension has been an ongoing debate for several years. HCTZ is widely used in the form of single-pill combinations, whereas CTD is a more potent drug vs. HCTZ, especially in reducing nighttime blood pressure (BP), with some indirect evidence suggesting a superiority in terms of cardiovascular (CV) risk reduction. In addition, recent data showed that CTD was safe and effective in terms of BP lowering in p...
Source: Hellenic Journal of Cardiology - July 10, 2023 Category: Cardiology Authors: Anastasios Kollias Konstantinos G Kyriakoulis George S Stergiou Source Type: research
The effect of intraoperative goal-directed fluid therapy combined with enhanced recovery after surgery program on postoperative complications in elderly patients undergoing thoracoscopic pulmonary resection: a prospective randomized controlled study
ConclusionsUnder ERAS program, there was no significant difference of AKI incidence between GDFT and RFT in elderly patients undergoing thoracoscopic pulmonary resection. But postoperative increase degree of serum creatinine was lower in GDFT group.Trial registrationRegistered at ClinicalTrials.gov, NCT04302467 on 26 February 2020.
Source: Perioperative Medicine - July 10, 2023 Category: Surgery Source Type: research
Nanoparticle-mediated delivery of microRNAs-based therapies for treatment of disorders
Pathol Res Pract. 2023 Jul 3;248:154667. doi: 10.1016/j.prp.2023.154667. Online ahead of print.ABSTRACTmiRNAs represent appropriate candidates for treatment of several disorders. However, safe and efficient delivery of these small-sized transcripts has been challenging. Nanoparticle-based delivery of miRNAs has been used for treatment of a variety of disorders, particularly cancers as well as ischemic stroke and pulmonary fibrosis. The wide range application of this type of therapy is based on the important roles of miRNAs in the regulation of cell behavior in physiological and pathological conditions. Besides, the ability...
Source: Pathology, Research and Practice - July 9, 2023 Category: Pathology Authors: Soudeh Ghafouri-Fard Hamed Shoorei Leili Noferesti Bashdar Mahmud Hussen Mohammad Hossein Behzad Moghadam Mohammad Taheri Fariborz Rashnoo Source Type: research
Molecular Mechanisms of Lipid-Based Metabolic Adaptation Strategies in Response to Cold
Cells. 2023 May 10;12(10):1353. doi: 10.3390/cells12101353.ABSTRACTTemperature changes and periods of detrimental cold occur frequently for many organisms in their natural habitats. Homeothermic animals have evolved metabolic adaptation strategies to increase mitochondrial-based energy expenditure and heat production, largely relying on fat as a fuel source. Alternatively, certain species are able to repress their metabolism during cold periods and enter a state of decreased physiological activity known as torpor. By contrast, poikilotherms, which are unable to maintain their internal temperature, predominantly increase me...
Source: Cancer Control - July 6, 2023 Category: Cancer & Oncology Authors: Gang Wu Ralf Baumeister Thomas Heimbucher Source Type: research
