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Metabolic Aspects of Adenosine Functions in the Brain
Adenosine, acting both through G-protein coupled adenosine receptors and intracellularly, plays a complex role in multiple physiological and pathophysiological processes by modulating neuronal plasticity, astrocytic activity, learning and memory, motor function, feeding, control of sleep and aging. Adenosine is involved in stroke, epilepsy and neurodegenerative pathologies. Extracellular concentration of adenosine in the brain is tightly regulated. Adenosine may be generated intracellularly in the central nervous system from degradation of AMP or from the hydrolysis of S-adenosyl homocysteine, and then exit via bi-directio...
Source: Frontiers in Pharmacology - May 14, 2021 Category: Drugs & Pharmacology Source Type: research

Impact of COVID-19 pandemic lockdown on occupational therapy practice and use of telerehabilitation - A cross sectional study
CONCLUSIONS: The COVID-19 pandemic lockdown experiences made us rethink the current approach of therapy services into alternative method (mixed mode) delivery of occupational therapy practice, which is including the combined method of video-based (telerehabilitation) consultation and face to face intervention.PMID:34002837 | DOI:10.26355/eurrev_202105_25845
Source: Pharmacological Reviews - May 18, 2021 Category: Drugs & Pharmacology Authors: B Ganesan K N K Fong S K Meena P Prasad R K Y Tong Source Type: research

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