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Long-standing persistent effects of atrial volume reduction combined with pulmonary vein isolation
Publication date: Available online 18 June 2018 Source:Journal of Cardiology Cases Author(s): Masami Takagaki, Naoko Ikeda, Hiroki Yamaguchi, Shinichi Mitsuyama, Tasuku Kadowaki, Tatsuya Nakao Although surgical left atrial (LA) volume reduction combined with mitral valve surgery and/or surgical ablation for atrial fibrillation has been reported to be effective, its long-term outcomes in the absence of mitral procedure are not well established. A 74-year-old man with two previous sternotomies—the first for pericardiectomy due to constrictive pericarditis and the second for mitral valve replacement with mechanical valve a...
Source: Journal of Cardiology Cases - June 20, 2018 Category: Cardiology Source Type: research

Editors' Choice Stroke prevention: Learning from the master (and COMMANDER)
Adding rivaroxaban to standard therapy in patients with heart failure and no atrial fibrillation did not show any beneficial effect on death risk.
Source: Science Translational Medicine - September 19, 2018 Category: Biomedical Science Authors: Santulli, G. Tags: Editors ' Choice Source Type: research

Adult and pediatric mechanical circulation: a guide for the hematologist.
Authors: Kreuziger LB, Massicotte MP Abstract Mechanical circulatory support (MCS) is the overarching term that encompasses the temporary and durable devices used in patients with severe heart failure. MCS disturbs the hematologic and coagulation system, leading to platelet activation, activation of the contact pathway of coagulation, and acquired von Willebrand syndrome. Ischemic stroke and major hemorrhage occur in up to 30% of patients. Hematologists are an essential part of the MCS team because they understand the delicate balance between bleeding and clotting and alteration of hemostasis with antithrombotic th...
Source: Hematology ASH Education Program - December 7, 2018 Category: Hematology Tags: Hematology Am Soc Hematol Educ Program Source Type: research

Relative Prognostic Importance and Optimal Levels of Risk Factors for Mortality and Cardiovascular Outcomes in Type 1 Diabetes.
CONCLUSIONS: Glycated hemoglobin, albuminuria, duration of diabetes, systolic blood pressure and low-density lipoprotein cholesterol appear the most important predictors for mortality and cardiovascular outcomes in patients with type 1 diabetes. Lower levels for glycated hemoglobin, systolic blood pressure and low-density lipoprotein cholesterol than contemporary guideline target levels appear to be associated with significantly lower risk for outcomes. PMID: 30798638 [PubMed - as supplied by publisher]
Source: Circulation - February 25, 2019 Category: Cardiology Authors: Rawshani A, Rawshani A, Sattar N, Franzén S, McGuire DK, Eliasson B, Svensson AM, Zethelius B, Miftaraj M, Rosengren A, Gudbjörnsdottir S Tags: Circulation Source Type: research

The usefulness of case studies in a Virtual Clinical Environment (VCE) multimedia courseware in nursing.
Authors: Bonito SR Abstract Clinical practicum is a major component in nursing education. Students are able to apply their classroom learning to the actual care setting. The clinical practicum setting must provide an authentic environment where students can maximize learning opportunities and demonstrate knowledge, skills, and attitude in caring for patients. Herein lies the challenge. The real world setting and timing may not be enough for students to learn the many complex tasks demanded as course outcomes and expected competencies. The purpose of this study was to describe the usefulness of using multimedia case...
Source: Journal of Medical Investigation - May 10, 2019 Category: General Medicine Tags: J Med Invest Source Type: research

Published Study Supports MyoKardia ’s Wrist-Worn Biosensor
MyoKardia’s said data on its wrist-worn digital health device was published in an article titled, “Machine Learning Detection of Obstructive Hypertrophic Cardiomyopathy (oHCM) Using a Wearable Biosensor,” in the Nature Partner Journal, Digital Medicine. The South San Francisco-based company said results from an exploratory study provided encouraging evidence of the potential for a wrist-worn biosensor to screen for obstructive hypertrophic cardiomyopathy. The study demonstrated that continuous monitoring using a wrist-worn photoplethysmography (PPG) digital health devic...
Source: MDDI - June 24, 2019 Category: Medical Devices Authors: MDDI Staff Tags: Business Cardiovascular Source Type: news

An artificial intelligence-enabled ECG algorithm for the identification of patients with atrial fibrillation during sinus rhythm: a retrospective analysis of outcome prediction
Publication date: Available online 1 August 2019Source: The LancetAuthor(s): Zachi I Attia, Peter A Noseworthy, Francisco Lopez-Jimenez, Samuel J Asirvatham, Abhishek J Deshmukh, Bernard J Gersh, Rickey E Carter, Xiaoxi Yao, Alejandro A Rabinstein, Brad J Erickson, Suraj Kapa, Paul A FriedmanSummaryBackgroundAtrial fibrillation is frequently asymptomatic and thus underdetected but is associated with stroke, heart failure, and death. Existing screening methods require prolonged monitoring and are limited by cost and low yield. We aimed to develop a rapid, inexpensive, point-of-care means of identifying patients with atrial ...
Source: The Lancet - August 2, 2019 Category: General Medicine Source Type: research

Screening mammography beyond breast cancer: breast arterial calcifications as a sex-specific biomarker of cardiovascular risk
ConclusionsThere is a strong rationale for mammography to become a dual test for breast cancer screening and CV disease prevention. However, robust and automated quantification methods are needed for a deeper insight on the association between BAC and CV disease, to stratifying CV risk and define personalized preventive actions.Graphical abstract
Source: European Journal of Radiology - August 12, 2019 Category: Radiology Source Type: research

Alzheimer's dementia: pathogenesis and impact of cardiovascular risk factors on cognitive decline.
Authors: Wanleenuwat P, Iwanowski P, Kozubski W Abstract Alzheimer's disease (AD) is the most common form of dementia manifesting as alterations in cognitive abilities, behavior and deterioration in memory which is progressive, leading to gradual worsening of symptoms. Major pathological features of AD are accumulations of neuronal amyloid plaques and neurofibrillary tangles, with early lesions appearing primarily in the hippocampus, the area of the brain involved in memory and learning. Cardiovascular related risk factors are believed to play a crucial role in disease development and the acceleration of cognitive ...
Source: Postgraduate Medicine - August 21, 2019 Category: Internal Medicine Tags: Postgrad Med Source Type: research

Possible Consequences of Parathyroidectomy on Hypertension in Primary Hyperparathyroidism
When counseling patients regarding the potential benefits of parathyroidectomy for primary hyperparathyroidism (PHPT), surgeons discuss the possible short-term and long-term consequences of operation. The short-term benefits may include alleviation of fatigue, bone aches, depressed mood, and frequent urination. While it is extremely rewarding to improve these symptoms, it is the long-term benefits that may be truly life-altering and potentially lifesaving. The organs most likely to be negatively affected by PHPT are the bones, kidneys, brain, and heart. Medical students everywhere still learn about the effects of this dise...
Source: JAMA Surgery - October 9, 2019 Category: Sports Medicine Source Type: research

Phenomapping of patients with heart failure with preserved ejection fraction using machine learning ‐based unsupervised cluster analysis
ConclusionsMachine learning ‐based cluster analysis can identify phenogroups of patients with HFpEF with distinct clinical characteristics and long‐term outcomes.
Source: European Journal of Heart Failure - October 20, 2019 Category: Cardiology Authors: Matthew W. Segar, Kershaw V. Patel, Colby Ayers, Mujeeb Basit, W.H. Wilson Tang, Duwayne Willett, Jarett Berry, Justin L. Grodin, Ambarish Pandey Tags: Research Article Source Type: research

What ’s the Big Deal about Data in Medtech?
Discussion, “Top 5 Things You Need to Know about the Implantable Internet of Things." Brian Chapman, partner and leader of ZS’s medtech practice of ZS, attributes today’s focus on data to the intersection of two important things: "A general recognition that understanding more and connecting actions with outcomes will provide feedback and understanding that will drive standards of care. This is not new, but as capabilities rise in data collection, aggregation, and synthesize rise, and coupled with machine learning, the promise of data in healthcare is becoming even more ...
Source: MDDI - December 20, 2019 Category: Medical Devices Authors: Daphne Allen Tags: Digital Health Source Type: news

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