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Procedure: Perfusion

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Total 2334 results found since Jan 2013.

Early Insulin Glycemic Control Combined With tPA Thrombolysis Reduces Acute Brain Tissue Damages in a Focal Embolic Stroke Model of Diabetic Rats Brief Reports
Conclusions— Early insulin glycemic control may be beneficial in combination with tPA thrombolysis for ischemic stroke with diabetes mellitus or poststroke hyperglycemia.
Source: Stroke - December 24, 2012 Category: Neurology Authors: Fan, X., Ning, M., Lo, E. H., Wang, X. Tags: Animal models of human disease, Type 1 diabetes, Acute Cerebral Infarction, Embolic stroke, Emergency treatment of Stroke, Thrombolysis Brief Reports Source Type: research

Utility of Computed Tomographic Perfusion in Thrombolysis for Minor Stroke Brief Reports
Conclusions— In selected MIS patients with demonstrable penumbra on computed tomographic perfusion, IV-tPA is safe and associated with significant improvement in functional outcome at discharge and 90 days.
Source: Stroke - June 26, 2016 Category: Neurology Authors: Ng, F. C., Coote, S., Frost, T., Bladin, C., Choi, P. M. Tags: Computerized Tomography (CT), Diagnostic Testing, Treatment, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Remote Ischemic Perconditioning as an Adjunct Therapy to Thrombolysis in Patients With Acute Ischemic Stroke: A Randomized Trial Clinical Sciences
Conclusions— Although the overall results were neutral, a tissue survival analysis suggests that prehospital rPerC may have immediate neuroprotective effects. Future clinical trials should take such immediate effects, and their duration, into account. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00975962.
Source: Stroke - December 23, 2013 Category: Neurology Authors: Hougaard, K. D., Hjort, N., Zeidler, D., Sorensen, L., Norgaard, A., Hansen, T. M., von Weitzel-Mudersbach, P., Simonsen, C. Z., Damgaard, D., Gottrup, H., Svendsen, K., Rasmussen, P. V., Ribe, L. R., Mikkelsen, I. K., Nagenthiraja, K., Cho, T.-H., Reding Tags: Emergency treatment of Stroke, Computerized tomography and Magnetic Resonance Imaging, Neuroprotectors, Thrombolysis Clinical Sciences Source Type: research

Cortical Venous Filling on Dynamic Computed Tomographic Angiography: A Novel Predictor of Clinical Outcome in Patients With Acute Middle Cerebral Artery Stroke Clinical Sciences
Conclusions— The combination of extent and velocity of optimal CVF, as assessed with dynamic CT angiography, is useful to identify patients with acute middle cerebral artery stroke at higher risk of poor clinical outcome at 3-month follow-up. Clinical Trial Registration— URL: http://www.trialregister.nl/trialreg and http://www.clinicaltrials.gov. Unique identifier: NTR1804 and NCT00880113, respectively.
Source: Stroke - February 22, 2016 Category: Neurology Authors: van den Wijngaard, I. R., Wermer, M. J. H., Boiten, J., Algra, A., Holswilder, G., Meijer, F. J. A., Dippel, D. W. J., Velthuis, B. K., Majoie, C. B. L. M., van Walderveen, M. A. A. Tags: Computerized Tomography (CT), Imaging, Prognosis, Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Prediction of Stroke Onset Is Improved by Relative Fluid-Attenuated Inversion Recovery and Perfusion Imaging Compared to the Visual Diffusion-Weighted Imaging/Fluid-Attenuated Inversion Recovery Mismatch Clinical Sciences
Conclusions— In patients with unknown stroke onset, the accuracy of predicting time from symptom onset within 4.5 hours is improved by obtaining relative FLAIR and perfusion imaging.
Source: Stroke - September 25, 2016 Category: Neurology Authors: Wouters, A., Dupont, P., Norrving, B., Laage, R., Thomalla, G., Albers, G. W., Thijs, V., Lemmens, R. Tags: Magnetic Resonance Imaging (MRI), Treatment, Ischemic Stroke Clinical Sciences Source Type: research

Agreement Among Stroke Faculty and Fellows in Treating Ischemic Stroke Patients With Tissue-Type Plasminogen Activator and Thrombectomy Brief Report
Conclusions—We found substantial agreement between vascular neurology fellows and faculty in treating with tissue-type plasminogen activator or IAT. Areas for improvement include recognition of stroke mimics, consensus on treating less severe strokes, and use/interpretation of imaging.
Source: Stroke - December 22, 2016 Category: Neurology Authors: Ahmad-Riad Ramadan, Mary Carter Denny, Farhaan Vahidy, Jose-Miguel Yamal, Tzu-Ching Wu, Amrou Sarraj, Sean Savitz, James Grotta Tags: Quality and Outcomes, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Prevalence of Imaging Biomarkers to Guide the Planning of Acute Stroke Reperfusion Trials Brief Report
Conclusions—As part of the feasibility analysis in stroke clinical trials, this analysis and the resulting tables can help investigators determine sample size and the number needed to screen.
Source: Stroke - May 22, 2017 Category: Neurology Authors: Bin Jiang, Robyn L. Ball, Patrik Michel, Tudor Jovin, Manisha Desai, Ashraf Eskandari, Zack Naqvi, Max Wintermark Tags: Computerized Tomography (CT), Ischemic Stroke Brief Reports Source Type: research

Alberta Stroke Program Early CT Scale Evaluation of Multimodal Computed Tomography in Predicting Clinical Outcomes of Stroke Patients Treated With Aspiration Thrombectomy Clinical Sciences
Conclusions— CT perfusion parameters, evaluated with ASPECTS, are optimal predictors of outcome and are more sensitive and specific than CT ASPECTS in the prediction of favorable outcome. Use of these parameters in treatment decisions could reduce futile recanalizations.
Source: Stroke - July 22, 2013 Category: Neurology Authors: Psychogios, M.-N., Schramm, P., Frolich, A. M., Kallenberg, K., Wasser, K., Reinhardt, L., Kreusch, A. S., Jung, K., Knauth, M. Tags: CT and MRI, Other diagnostic testing, Acute Cerebral Infarction, Emergency treatment of Stroke, Thrombolysis Clinical Sciences Source Type: research

Systematic Review, Critical Appraisal, and Analysis of the Quality of Economic Evaluations in Stroke Imaging Clinical Sciences
Conclusions— Economic evaluations of imaging modalities after acute ischemic stroke were generally of high methodological quality. However, important radiology-specific clinical components were missing from all of these analyses.
Source: Stroke - February 24, 2014 Category: Neurology Authors: Burton, K. R., Perlis, N., Aviv, R. I., Moody, A. R., Kapral, M. K., Krahn, M. D., Laupacis, A. Tags: CT and MRI, Acute Stroke Syndromes, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Sensitivity of Diffusion- and Perfusion-Weighted Imaging for Diagnosing Acute Ischemic Stroke Is 97.5% Clinical Sciences
Conclusions— The combination of DWI and PWI before intravenous tissue-type plasminogen activator confirms the diagnosis in 97.5% of all ischemic strokes.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Simonsen, C. Z., Madsen, M. H., Schmitz, M. L., Mikkelsen, I. K., Fisher, M., Andersen, G. Tags: Imaging, Acute Cerebral Infarction, Emergency treatment of Stroke, Thrombolysis Clinical Sciences Source Type: research

Inhibition of CD147 (Cluster of Differentiation 147) Ameliorates Acute Ischemic Stroke in Mice by Reducing Thromboinflammation Basic Sciences
Conclusions—Inhibition of CD147 ameliorates acute ischemic stroke by reducing thromboinflammation. CD147 might represent a novel and promising therapeutic target for ischemic stroke and possibly other thromboinflammatory disorders.
Source: Stroke - November 27, 2017 Category: Neurology Authors: Rong Jin, Adam Y. Xiao, Rui Chen, D. Neil Granger, Guohong Li Tags: Basic Science Research, Ischemic Stroke Original Contributions Source Type: research

Perfusion MR Predicts Outcome in High-Risk Transient Ischemic Attack/Minor Stroke: A Derivation-Validation Study Clinical Sciences
Conclusions— Among subjects with high-risk transient ischemic attack and minor stroke, diffusion-weighted imaging–perfusion-weighted imaging mismatch predicts infarct growth and clinical deterioration. These findings suggest that reperfusion strategies would be beneficial in this population.
Source: Stroke - August 26, 2013 Category: Neurology Authors: Asdaghi, N., Hill, M. D., Coulter, J. I., Butcher, K. S., Modi, J., Qazi, A., Goyal, M., Demchuk, A. M., Coutts, S. B. Tags: CT and MRI, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

FTY720 Ameliorates Acute Ischemic Stroke in Mice by Reducing Thrombo-Inflammation but Not by Direct Neuroprotection Basic Sciences
Conclusions— Induction of lymphocytopenia and concomitant reduction of microvascular thrombosis are key modes of FTY720 action in stroke. In contrast, our findings in Rag1–/– mice and cultured neurons argue against direct neuroprotective effects of FTY720.
Source: Stroke - October 21, 2013 Category: Neurology Authors: Kraft, P., Gob, E., Schuhmann, M. K., Gobel, K., Deppermann, C., Thielmann, I., Herrmann, A. M., Lorenz, K., Brede, M., Stoll, G., Meuth, S. G., Nieswandt, B., Pfeilschifter, W., Kleinschnitz, C. Tags: Animal models of human disease, Ischemic biology - basic studies, Acute Cerebral Infarction, Pathology of Stroke, Anticoagulants Basic Sciences Source Type: research

Immediate Changes in Stroke Lesion Volumes Post Thrombolysis Predict Clinical Outcome Clinical Sciences
Conclusions— Reversal of the DWI volume at 24 hours because of immediate reperfusion in patients post thrombolysis is predictive of favorable clinical outcome.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Luby, M., Warach, S. J., Nadareishvili, Z., Merino, J. G. Tags: Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging, Pathology of Stroke, Thrombolysis Clinical Sciences Source Type: research

Time-Resolved C-Arm Computed Tomographic Angiography Derived From Computed Tomographic Perfusion Acquisition: New Capability for One-Stop-Shop Acute Ischemic Stroke Treatment in the Angiosuite Clinical Sciences
Conclusions— Time-resolved CTAs derived from C-arm CT perfusion acquisitions provide high quality images that allowed accurate diagnosis of large vessel occlusions. Although image quality of smaller arteries in this study was not optimal ongoing modifications of the postprocessing algorithm will likely remove this limitation. Adding time-resolved C-arm CTAs to the capabilities of the angiography suite further enhances its suitability as a one-stop shop for care for patients with acute ischemic stroke.
Source: Stroke - November 23, 2015 Category: Neurology Authors: Yang, P., Niu, K., Wu, Y., Struffert, T., Dorfler, A., Schafer, S., Royalty, K., Strother, C., Chen, G.-H. Tags: Angiography, Diagnostic Testing, Imaging, Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research