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Total 290 results found since Jan 2013.
The Role of Ferroptosis in Nervous System Disorders
J Integr Neurosci. 2023 Jan 16;22(1):19. doi: 10.31083/j.jin2201019.ABSTRACTFerroptosis is distinct from other apoptotic forms of programmed cell death and is characterized by the accumulation of iron and lipid peroxidation. Iron plays a crucial role in the oxidation of lipids via the Fenton reaction with oxygen. Hence, iron accumulation causes phospholipid peroxidation which induces ferroptosis. Moreover, detoxification by glutathione is disrupted during ferroptosis. A growing number of studies have implicated ferroptosis in nervous system disorders such as depression, neurodegenerative disease, stroke, traumatic brain in...
Source: Journal of Integrative Neuroscience - February 1, 2023 Category: Neuroscience Authors: Lixia Du You Wu Zhongmin Fan Yi Li Xiaofeng Guo Zongping Fang Xijing Zhang Source Type: research
Pollutants In Your Salt!?
Your doctor, the media, and the medical establishment continue to warn that flavoring your food with salt will kill you. They link sodium consumption to a higher risk of high blood pressure, stroke – and of course, heart disease.
As usual, the powers that be are missing the real picture…
You see, salt has been part of human life for thousands of years – long before these chronic diseases became as common as they are today.
Humans started adding salt to their food for more than 5,000 years. It was the most effective way to preserve food.
Some historians even go as far as to credit salt for the development of human civ...
Source: Al Sears, MD Natural Remedies - December 23, 2022 Category: Complementary Medicine Authors: Jacob Tags: Anti-Aging Health Source Type: news
A bibliometric analysis of cerebral microbleeds and cognitive impairment
CONCLUSION: This bibliometric analysis reveals a strong link between CMBs and cognitive impairment-related diseases and that specific brain networks were affected by CMBs. This provides further insights into the possible mechanisms and causes of CMBs and cognitive impairment. The direct and indirect damage (such as oxidative stress and neuroinflammation) to the brain caused by CMBs, destruction of the frontal-subcortical circuits, elevated Cystatin C levels, and iron deposition are involved in the occurrence and development of cognitive impairment. CMBs may be a potential marker for detecting, quantifying, and predicting c...
Source: Brain and Cognition - June 1, 2023 Category: Neurology Authors: Rui Yang Jia Li Yaya Qin Li Zhao Rong Liu Fanhui Yang Guohui Jiang Source Type: research
Using Aspirin Every Day May Cause Anemia in Seniors
A new study suggests regular aspirin use in older adults may pose a serious risk of anemia, adding to existing research that challenges the long-established recommendation to use aspirin as a preventative therapy for dangerous cardiac events. The results come just a year after a national independent task force updated formal recommendations in April 2022 cautioning those over the age of 60 against beginning a daily aspirin regimen.
For decades, aspirin has been used like a vitamin by a sizable portion of America’s aging population. Research as far back as the 1950s showed a daily low dose of the anti-inflammatory me...
Source: TIME: Health - June 21, 2023 Category: Consumer Health News Authors: Haley Weiss Tags: Uncategorized Aging healthscienceclimate Source Type: news
Enhancement of combustion effect leading to improved performance and exhaust emissions of an SI engine with ferrous oxide and graphite nanoparticles
Environ Sci Pollut Res Int. 2023 Aug 8. doi: 10.1007/s11356-023-28556-z. Online ahead of print.ABSTRACTThe present study was conducted to investigate the effectiveness of new, less toxic, less harmful, and nonmetallic graphite (G) and metallic iron oxide (Fe2O3) nanofuel additives by analyzing experimentally their consequences on exhaust emissions and performance of an air cooled, single cylinder, 4-stroke gasoline engine. Fe2O3 and graphite nanoparticles at 40, 80, and 120 mg/l of gasoline concentrations were mixed with gasoline by means of a magnetic stirrer. Brake power (BP), brake-specific fuel consumption (BSFC), torq...
Source: Environmental Science and Pollution Research International - August 8, 2023 Category: Environmental Health Authors: Yasir Hussain Siddiqui Muhammad Shakaib Adnan Rasheed Hafiz Muhammad Ali Syed Mohammad Rizwan Azeem Athar Husain Siddique Muhammad Shafiq Source Type: research
Detection of Ferroptosis in Models of Brain Diseases
Methods Mol Biol. 2023;2712:233-251. doi: 10.1007/978-1-0716-3433-2_21.ABSTRACTFerroptosis is a regulated form of non-apoptotic cell death driven by iron-dependent lipid peroxidation. In the past decade, ferroptosis has been reported to be involved in the pathological role in the central nervous system degenerative diseases (e.g., Alzheimer's disease, Huntington's disease, and Parkinson's disease), stroke, traumatic brain injury, and brain tumor. However, how to reliably detect and classify ferroptosis from other cell death in pathological conditions remains a great challenge, especially in primary brain cells and brain ti...
Source: Mol Biol Cell - August 14, 2023 Category: Molecular Biology Authors: Danmin Shen Fei Yang Qian Li Source Type: research
