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Condition: Reflex Sympathetic Dystrophy
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Total 611 results found since Jan 2013.

The endogenous and exogenous brain-derived neurotrophic factor plays pivotal roles in the pathogenesis of stroke onset in high salt-loaded hypertensive rats.
Abstract Brain-derived neurotrophic factor (BDNF) is known to have neuroprotective effects on multiple neurovascular diseases especially poststroke recovery. On the other hand, BDNF reported to increase blood pressure (BP) which is one of the major risk factor for stroke onset. To clarify the conflicting effects on stroke onset, we examined the expression of endogenous BDNF in relation to stroke onset. In addition, we explored the effect of exogenous central BDNF against stroke onset and all-cause mortality as the primary endpoint and BP as the secondary object in hypertensive rats with high-salt diet. In experime...
Source: Experimental Gerontology - February 17, 2021 Category: Geriatrics Authors: Hasegawa Y, Takemoto Y, Hayashi K, Kameno K, Kim-Mitsuyama S Tags: Exp Gerontol Source Type: research

Longitudinal changes in the hypothalamic –pituitary–adrenal axis and sympathetic nervous system are related to the prognosis of stroke
ConclusionsStroke causes significant time-phased dynamic changes in the hypothalamic–pituitary–adrenal axis and sympathetic nervous system, and plasma F, ACTH, and urinary NE levels can be used to assess stroke severity and prognosis.Chinese clinical trial registryRegistration Number: ChiCTR1900024992. Registration Date: 2019/8/6.
Source: Frontiers in Neurology - July 27, 2022 Category: Neurology Source Type: research

Relation of Serial Hemodynamic and Autonomic Changes in Acute Ischemic Stroke to Stroke Type, Location and Outcome. (P3.094)
Conclusion: Hypertension in AIS may be mediated predominantly by changes in SVR. Hemodynamic and autonomic parameters may predict outcome and possibly stroke location. Further studies among patients with homogenous stroke types may help understand the interaction between focal brain injury and autonomic changes.Study funded by: Dean's Fund, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, OmanDisclosure: Dr. Gujjar has nothing to disclose. Dr. Jaju has nothing to disclose. Dr. Poovathur has nothing to disclose. Dr. Dikshit has nothing to disclose. Dr. Al-Asmi has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Gujjar, A., Jaju, D., Poovathur, J., Dikshit, M., Al-Asmi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Clinical Management Source Type: research

VOR Gain by Head Impulse Video-Oculography Differentiates Acute Vestibular Neuritis from Stroke
Conclusion: Video HIT VOR gains differ between peripheral and central causes of AVS. PICA strokes were readily separated from neuritis using gain measures, but AICA strokes were at risk of being misclassified based on VOR gain alone.
Source: Otology and Neurotology - February 13, 2015 Category: ENT & OMF Tags: Vestibular Disorders Source Type: research

Pre-Stroke Use of Beta-Blockers Does Not Lower Post-Stroke Infection Rate: An Exploratory Analysis of the Preventive Antibiotics in Stroke Study
This study is aimed at investigating the association between BB treatment at baseline and post-stroke infection in the Preventive Antibiotics in Stroke Study (PASS), a prospective clinical trial.Methods: We performed an exploratory analysis in PASS, 2,538 patients with acute phase of stroke (24 h after onset) were randomized to ceftriaxone (intravenous, 2 g per day for 4 days) in addition to stroke unit care, or standard stroke unit care without preventive antibiotic treatment. All clinical data, including use of BBs, was prospectively collected. Infection was diagnosed by the treating physician, and independently by an ex...
Source: Cerebrovascular Diseases - October 4, 2016 Category: Neurology Source Type: research

Impaired H-Reflex Adaptations Following Slope Walking in Individuals With Post-stroke Hemiparesis
ConclusionSimilar pattern of change in peak propulsive and braking forces with respect to different slopes was observed in both individuals post-stroke and non-impaired individuals, but the magnitude of GRFs were smaller in individuals post-stroke due to the slower walking speed. Our results suggested that impaired modulation of the H-reflex pathway potentially underlies the lack of neuroadaptations in individuals with chronic post-stroke hemiparesis.
Source: Frontiers in Physiology - September 30, 2019 Category: Physiology Source Type: research

The endogenous and exogenous brain-derived neurotrophic factor plays pivotal roles in the pathogenesis of stroke onset in high salt-loaded hypertensive rats
Exp Gerontol. 2021 Feb 17;147:111286. doi: 10.1016/j.exger.2021.111286. Online ahead of print.ABSTRACTBrain-derived neurotrophic factor (BDNF) is known to have neuroprotective effects on multiple neurovascular diseases especially poststroke recovery. On the other hand, BDNF reported to increase blood pressure (BP) which is one of the major risk factors for stroke onset. To clarify the conflicting effects on stroke onset, we examined the expression of endogenous BDNF in relation to stroke onset. In addition, we explored the effect of exogenous central BDNF against stroke onset and all-cause mortality as the primary endpoint...
Source: Experimental Gerontology - February 20, 2021 Category: Geriatrics Authors: Yu Hasegawa Yushin Takemoto Kenyu Hayashi Koki Kameno Shokei Kim-Mitsuyama Source Type: research

Targeting brain-spleen crosstalk after stroke: new insights into stroke pathology and treatment
Curr Neuropharmacol. 2021 Mar 15. doi: 10.2174/1570159X19666210316092225. Online ahead of print.ABSTRACTThe immune response following acute stroke has received great attention. The spleen is an important immune organ, and more and more studies have shown that brain-spleen crosstalk after stroke plays an important role in its development and prognosis. There are many mechanisms of spleen activation after stroke, including activation of the sympathetic nervous system, the production of chemokines, and antigen presentation in the damaged brain. The changes in the spleen after stroke are mainly reflected in morphology, changes...
Source: Current Neuropharmacology - March 17, 2021 Category: Drugs & Pharmacology Authors: Dong Han Hang Liu Yan Gao Juan Feng Source Type: research