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Total 923 results found since Jan 2013.

Low Hemoglobin Increases Risk for Stroke, Kidney Disease, Elevated Estimated Pulmonary Artery Systolic Pressure, and Premature Death in Sickle Cell Disease: A Systematic Literature Review and Meta-Analysis
Conclusions: In conclusion, comprehensive evaluation of peer-reviewed literature published over the past 20 years demonstrates a significant relationship between chronic anemia and worse clinical outcomes in individuals with SCD. Meta-analyses further demonstrate that even relatively modest differences in hemoglobin are important and support hemoglobin increase by ≥1 g/dL as a relevant therapeutic target. These results suggest that interventions that reduce hemolytic anemia may confer clinical benefit in this patient population.DisclosuresAtaga: Novartis: Consultancy, Honoraria; Bioverativ: Honoraria, Membership on an e...
Source: Blood - November 21, 2018 Category: Hematology Authors: Ataga, K. I., Gordeuk, V. R., Allen, I. E., Colby, J., Gittings, K., Agodoa, I. Tags: 114. Hemoglobinopathies, Excluding Thalassemia-Clinical: Organ Damage and Clinical Complications in Sickle Cell Disease Source Type: research

Important New Results in Stroke Important New Results in Stroke
Results from the International Stroke Conference 2019: Dr Christoph Diener discusses recent positive and neutral trial results.Medscape Neurology
Source: Medscape Neurology and Neurosurgery Headlines - March 26, 2019 Category: Neurology Tags: Neurology & Neurosurgery Commentary Source Type: news

Efficacy of sertraline for post-stroke depression: A systematic review protocol of randomized controlled trial
Conclusions: The results of this systematic review may summarize the up-to-date evidence on the efficacy and safety of sertraline for patients with PSD. Ethics and dissemination: This systematic review will not need any ethical approval, because it will not analyze any individual patient data. The findings of this study are expected to disseminate at peer-reviewed journals.
Source: Medicine - April 1, 2019 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

Robot-assisted therapy for arm recovery for stroke patients: state of the art and clinical implication.
This article reviews the state of the art and perspectives of robotics in post-stroke rehabilitation for upper limb recovery. Classifications and features of robots have been reported in accordance with technological and clinical contents, together with the definition of determinants specific for each patient, that could modify the efficacy of robotic treatments. The possibility of combining robotic intervention with other therapies has also been discussed.Expert commentary: The recent wide diffusion of robots in neurorehabilitation has generated a confusion due to the commingling of technical and clinical aspects not prev...
Source: Expert Review of Medical Devices - February 29, 2020 Category: Medical Devices Tags: Expert Rev Med Devices Source Type: research

Investigation of Invigorating Qi and Activating Blood Circulation Prescriptions in Treating Qi Deficiency and Blood Stasis Syndrome of Ischemic Stroke Patients: Study Protocol for a Randomized Controlled Trial
In this study, we intend to use similar prescriptions that invigorate Qi and activate blood circulation: Buyang Huanwu granules (BHG), Naoxintong capsules (NXTC), and Yangyin Tongnao granules (YTG). The goal is to evaluate their level of PSC inpatients with IS with QDBS syndrome and find relevant biomarkers to provide an objective basis for precise treatment of TCM and improve the clinical therapeutic effects. A multicenter, randomized, double-blinded, and placebo-controlled intervention trial will be conducted in IS patients with QDBS syndrome, followed by an add-on of Chinese patent medicine. A total of 160 subjects will...
Source: Frontiers in Pharmacology - June 16, 2020 Category: Drugs & Pharmacology Source Type: research

Efficacy and safety of intravenous thrombolysis with alteplase for treating acute ischemic stroke at different time windows: A protocol for systematic review and meta-analysis
Conclusions: This study will provide an evidence-based basis for the clinical efficacy of alteplase for treating AIS by thrombolytic therapy at different time windows. Ethics and dissemination: Private information from individuals will not be published. This systematic review also does not involve endangering participant rights. Ethical approval was not required. The results may be published in a peer-reviewed journal or disseminated at relevant conferences. OSF Registration number: DOI 10.17605 / OSF.IO / K7PHB
Source: Medicine - December 24, 2020 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

American Stroke Association, March 17-19
The annual International Stroke Conference of the American Heart Association/American Stroke Association was held virtually this year from March 17 to 19 and attracted participants from around the world, including cerebrovascular research and...
Source: Drugs.com - Pharma News - March 29, 2021 Category: Pharmaceuticals Source Type: news

AAN: Stroke Occurs in 2.2 Percent of Patients Admitted to ICU With COVID - 19
Cumulative hazard of death increased in association with hemorrhagic stroke, but not with ischemic stroke
Source: Pulmonary Medicine News - Doctors Lounge - April 19, 2021 Category: Respiratory Medicine Tags: Infections, Neurology, Nursing, Pulmonology, Critical Care, Conference News, Source Type: news

Chinese Cerebrovascular Neurosurgery Society and Chinese Interventional & Hybrid Operation Society, of Chinese Stroke Association Clinical Practice Guidelines for Management of Brain Arteriovenous Malformations in Eloquent Areas
Conclusions: The management of eloquent bAVMs remains challenging. With the evolutionary understanding of eloquent areas, the guideline highlights the assessment of eloquent bAVMs, and a strategy for decision-making in the management of eloquent bAVMs.
Source: Frontiers in Neurology - June 9, 2021 Category: Neurology Source Type: research

CMS renews reimbursements for Viz.ai stroke AI software
The U.S. Centers for Medicare and Medicaid Services (CMS) has renewed a reimbursemen...Read more on AuntMinnie.comRelated Reading: Viz.ai to add Avicenna.ai software to platform Viz.ai gets CE Mark for AI-powered stroke software Viz.ai touts research at stroke conference Viz.ai raises $71M in funding Viz.ai launches image software for clinical trials
Source: AuntMinnie.com Headlines - August 4, 2021 Category: Radiology Source Type: news

Effectiveness and safety of manual acupuncture therapy in patients with post-stroke depression: a protocol for a systematic review and meta-analysis
Introduction Acupuncture is widely used on the rehabilitation of stroke survivors, including hemiplegia, constipation, emotional disorders and so on. Although the effectiveness of manual acupuncture therapy on post-stroke depression (PSD) has been confirmed by multiple randomised controlled trials, there were few meta-analyses focused on the connection between different techniques, durations or other detailed operations of manual acupuncture and their effectiveness of improving the depression severity and quality of life for patients with PSD. Methods and analysis A systematic search will be performed on English databases...
Source: BMJ Open - December 10, 2021 Category: General Medicine Authors: Liu, W., Rao, C., Zhao, Q., Du, Y., Nan, X., Li, Z., Yin, C. Tags: Open access, Complementary medicine Source Type: research

Protocol for the economic evaluation of the China Salt Substitute and Stroke Study (SSaSS)
This study protocol describes the planned within-trial economic evaluation of a low-sodium salt substitute intervention designed to reduce the risk of stroke in China. Methods and analyses The economic evaluation will be conducted alongside the Salt Substitute and Stroke Study: a 5-year large scale, cluster randomised controlled trial. The outcomes of interest are quality of life measured using the EuroQol-5-Dimensions and major adverse cardiovascular events. Costs will be estimated from a healthcare system perspective and will be sought from the routinely collected data available within the New Rural Cooperative Medical ...
Source: BMJ Open - July 20, 2021 Category: General Medicine Authors: Li, K.-C., Tian, M., Neal, B., Huang, L., Yu, J., Liu, Y., Yin, X., Zhang, X., Wu, Y., Li, N., Elliott, P., Yan, L., Labarthe, D., Hao, Z., Shi, J., Feng, X., Zhang, J., Zhang, Y., Zhang, R., Zhou, B., Li, Z., Sun, J., Zhao, Y., Yu, Y., Si, L., Lung, T. Tags: Open access, Health economics Source Type: research

American Stroke Association, Feb. 9-11
The annual International Stroke Conference of the American Heart Association/American Stroke Association was held from Feb. 9 to 11 in New Orleans and attracted participants from around the world, including cerebrovascular research and practice...
Source: Drugs.com - Pharma News - February 22, 2022 Category: Pharmaceuticals Source Type: news

Effectiveness of transcranial direct current stimulation on hand dexterity in stroke patients: a protocol for a systematic review and meta-analysis
Introduction Hand dexterity is the ability to execute the skilful movements using the hand and fingers. It is commonly impaired poststroke resulting in a profound deterioration in the quality of life for patients with stroke. Transcranial direct current stimulation (tDCS) is a form of non-invasive brain stimulation, which has gained a popularity as an adjunct therapy in recovering motor dysfunction poststroke. Promising results have been gained from applying tDCS in combination with motor rehabilitation, however, the outcome of tDCS on the upper limb motor function poststroke has been varied. Different results are potentia...
Source: BMJ Open - February 16, 2022 Category: General Medicine Authors: Alabdulaali, L., Hickman, L., Punt, T. D., Jenkinson, N. Tags: Open access, Rehabilitation medicine Source Type: research

Feasibility of an individualised, task-oriented, video-supported home exercise programme for arm function in patients in the subacute phase after stroke: protocol of a randomised controlled pilot study
This study follows the Standard Protocol Items: Recommendations for Interventional Trials-Patient-Reported Outcome (PRO) Extension guideline. Ethical approval was received from the Ethics Committee of the Medical University of Innsbruck, Austria (1304/2020). Written informed consent will be obtained from all participants prior to data collection. Study results will be disseminated to participating patients, patient organisations, via the clinic’s homepage, relevant conferences and peer-reviewed journals. Trial registration number DRKS-ID: DRKS00023395. Study protocol, second revision, 5 December 2021.
Source: BMJ Open - January 4, 2022 Category: General Medicine Authors: Wanner, M., Schönherr, G., Kiechl, S., Knoflach, M., Müller, C., Seebacher, B. Tags: Open access, Neurology Source Type: research