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Stroke patients admitted within normal working hours are more likely to achieve process standards and to have better outcomes
Conclusions Patients with stroke admitted out of hours and at weekends or public holidays are less likely to be managed according to current guidelines. They experience poorer short-term outcomes than those admitted during normal working hours, after correcting for known independent predictors of outcome and early mortality.
Source: Journal of Neurology, Neurosurgery and Psychiatry - January 14, 2016 Category: Neurosurgery Authors: Turner, M., Barber, M., Dodds, H., Dennis, M., Langhorne, P., Macleod, M.-J., on behalf of the Scottish Stroke Care Audit Tags: Open access, Stroke, Radiology Cerebrovascular disease Source Type: research

Incidence, causes and predictors of neurological deterioration occurring within 24 h following acute ischaemic stroke: a systematic review with pathophysiological implications
Early neurological deterioration (END) following ischaemic stroke is a serious event with manageable causes in only a fraction of patients. The incidence, causes and predictors of END occurring within 24 h of acute ischaemic stroke (END24) have not been systematically reviewed. We systematically reviewed Medline and Embase from January 1990 to April 2013 for all studies on END24 following acute ischaemic stroke (<8 h from onset). We recorded the incidence and presumed causes of and factors associated with END24. Thirty-six studies were included. Depending on the definition used, the incidence of END24 markedly...
Source: Journal of Neurology, Neurosurgery and Psychiatry - December 17, 2014 Category: Neurosurgery Authors: Seners, P., Turc, G., Oppenheim, C., Baron, J.-C. Tags: Stroke Cerebrovascular disease Source Type: research

P014/130 Treatment of recurrent intracranial atherosclerotic disease-related stroke due to in-stent thrombosis with the CREDO(R) heal stent: A case report
ConclusionThis case highlights that re-stenting a recurrent ICAD-related stroke using the CREDO® heal stent is technically feasible, safe, and may improve clinical outcomes.Disclosure of InterestNothing to disclose.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Nguyen, A., Schulze-Zachau, V., Psychogios, M. Tags: 4.3 CASE PROPOSAL - Acute ischemic stroke Source Type: research

Endovascular Treatment and the Outcomes of Atherosclerotic Intracranial Stenosis in Patients With Hyperacute Stroke
CONCLUSION: Emergent intracranial angioplasty with or without stenting is safe and feasible and yields a high rate of revascularization and favorable outcome in patients with hyperacute stroke and underlying ICAS. Patients with underlying ICAS have less severe infarctions at presentation and higher successful revascularization after multimodal endovascular therapy in the setting of hyperacute stroke compared with those with other stroke subtypes. ABBREVIATIONS: ICAS, intracranial atherosclerotic stenosis MAT, manual aspiration thrombectomy mRS, modified Rankin Scale NIHSS, National Institutes of Health Stroke Scale SAMMPRI...
Source: Neurosurgery - May 19, 2015 Category: Neurosurgery Tags: Research-Human-Clinical Studies Source Type: research

Aspirin versus anticoagulation for stroke prophylaxis in blunt cerebrovascular injury: a propensity-matched retrospective cohort study
CONCLUSIONS: Therapeutic anticoagulation may be inferior to aspirin for stroke prevention in BCVI. Prospective research is warranted to definitively compare these treatment strategies.PMID:33770758 | DOI:10.3171/2020.10.JNS201836
Source: Journal of Neurosurgery - March 26, 2021 Category: Neurosurgery Authors: Robert H Bonow Cordelie E Witt Mahmud Mossa-Basha Joseph Cuschieri Saman Arbabi Monica S Vavilala Frederick P Rivara Randall M Chesnut Source Type: research

Timing and mechanism of ischemic stroke due to extracranial blunt traumatic cerebrovascular injury.
Conclusions Most ischemic strokes due to TCVI are embolic in nature and occur prior to screening CTA and initiation of treatment with aspirin. PMID: 23216467 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - December 7, 2012 Category: Neurosurgery Authors: Griessenauer CJ, Fleming JB, Richards BF, Cava LP, Curé JK, Younan DS, Zhao L, Alexandrov AV, Barlinn K, Taylor T, Harrigan MR Tags: J Neurosurg Source Type: research

Review of Toyoda K, et al. Dual antiplatelet therapy using cilostazol for secondary prevention in patients with high-risk ischemic stroke in Japan. Lancet Neurol. 2019 Jun;18(6):539-548.
Conclusion: This RCT demonstrated the safety of dual therapy, consisting of cilostazol/aspirin or cilostazol/ clopidogrel, in preventing secondary ischemic stroke in a high-risk Japanese population. Further studies are required to generalize these findings to other patient populations worldwide. PMID: 32363048 [PubMed]
Source: Surgical Neurology International - May 5, 2020 Category: Neurosurgery Tags: Surg Neurol Int Source Type: research

E-132 Successful mechanical thrombectomy in an 11-year-old patient with emergent large vessel occlusion acute ischemic stroke related to congenital complete heart block and recent covid-19 infection
ConclusionsThis is a first known report of a successful mechanical thrombectomy in a pediatric patient due to a large vessel occlusion related to congenital complete heart block and recent COVID-19 infection.Disclosures J. Ansari: None. D. Mata Canadas: None. M. Ayub: None. J. Caskey: None. P. Simoncini: None. R. Riel-Romero: None. P. Sharma: None. D. Jordan: None. H. Cuellar: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Ansari, J., Mata Canadas, D., Ayub, M., Caskey, J., Simoncini, P., Riel-Romero, R., Sharma, P., Jordan, D., Cuellar, H. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

Aspirin for primary prevention of stroke in traumatic cerebrovascular injury: association with increased risk of transfusion.
CONCLUSIONS Treatment with aspirin for the prevention of stroke in patients with initially asymptomatic TCVI carries a significantly increased risk of PRBC transfusion. Future studies are needed to determine if this risk is offset by a reduced risk of ischemic stroke. PMID: 29775142 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - May 18, 2018 Category: Neurosurgery Authors: Griffin RL, Falatko SR, Aslibekyan S, Strickland V, Harrigan MR Tags: J Neurosurg Source Type: research

E-020 Between a Rock and a Hard Place: The Use of Self-expanding Stents for the Endovascular Treatment of Acute Ischemic Stroke due to Recalcitrant Emergency Large Vessel Occlusion in the Era of Stent-retrievers: Single-center Experience and Early Results
ConclusionInitial results suggest that acute intracranial stenting may be beneficial in a subset of patients who present with an ELVO and who have failed recanalization by means of mechanical thrombectomy with stent-retrievers and/or thromboaspiration with large bore intracranial catheters.DisclosuresJ. Lozano: None. M. Howk: None. A. Kuhn: None. F. Massari: None. K. de Macedo Rodrigues: None. C. Brooks: None. M. Perras: None. M. Gounis: 1; C; NIH, Medtronic Neurovascular, Microvention/Terumo, Cerevasc LLC, Gentuity, Codman Neurovascular, Phillips Healthcare, Stryker Neurovascular, Tay Sachs Foundation, InNeuroCo Inc. 2; C...
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Lozano, J., Howk, M., Kuhn, A., Massari, F., de Macedo Rodrigues, K., Brooks, C., Perras, M., Gounis, M., Rex, D., Wakhloo, A., Puri, A. Tags: Electronic poster abstracts Source Type: research

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