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Atrial fibrillation (AF) pilot screening programme in primary care in Ireland: an implementation study protocol
This study aims to investigate the acceptability, feasibility and impact of AF screening in primary care using a handheld mobile ECG device. Methods and analysis General practitioners (GPs) and practice nurses in the South of Ireland will opportunistically screen patients aged ≥65 years for AF at routine consultation using a handheld one-lead ECG device, KardiaMobile. This study will screen up to 4000 patients. Blood pressure and smoking status will be checked concurrently. A mixed-method evaluation will be undertaken including a partial economic evaluation. Anonymised data will be collected from participating practice...
Source: BMJ Open - February 7, 2022 Category: General Medicine Authors: Callanan, A., Quinlan, D., O'Sullivan, S., Bradley, C. P., Kearney, P. M., Murphy, A., Buckley, C. M. Tags: Open access, Public health Source Type: research

Characteristics and management of patients with stroke and major hemorrhagic episodes with atrial fibrillation under vitamin K antagonist therapy. EVENTHO study
CONCLUSIONS: In the sample studied, half of the AF patients who suffered stroke/SE or major hemorrhagic episode had inadequate TTR and, despite this, after hospital discharge, they restarted treatment with VKA. These results highlight the need to evaluate safer and effective therapeutic alternatives in AF patients with poor TTR control after suffering a stroke/SE or major hemorrhagic episode.PMID:35120766 | DOI:10.1016/j.medcli.2021.12.004
Source: Medicina Clinica - February 5, 2022 Category: General Medicine Authors: Olga Gav ín Vanessa Rold án Pilar Llamas-Sillero Amparo Santamar ía Daniel Arum í Susana Fern ández de Cabo Source Type: research

Peripheral Arterial Disease, Stroke, and Mortality in Patients with Atrial Fibrillation
I read the paper by Vitalis et al1 with great interest. The authors assessed the impact of peripheral arterial disease on mortality and stroke in patients with atrial fibrillation. The adjusted hazard ratio (HR) (95% confidence interval [CI]) of peripheral arterial disease in patients with atrial fibrillation for all-cause mortality was 1.34 (1.06-1.70). In addition, the adjusted HR (95% CI) of peripheral arterial disease in patients with nonanticoagulated atrial fibrillation for ischemic stroke was 3.37 (1.25-9.09).
Source: The American Journal of Medicine - February 1, 2022 Category: General Medicine Authors: Tomoyuki Kawada Tags: Letter Source Type: research

Hypertrophic Cardiomyopathy: New Concepts and Therapies
Annu Rev Med. 2022 Jan 27;73:363-375. doi: 10.1146/annurev-med-042220-021539.ABSTRACTHypertrophic cardiomyopathy (HCM), a relatively common, globally distributed, and often inherited myocardial disorder, transformed over the last several years into a treatable condition with the emergence of effective management options that alter natural history at all ages. Now available are a matured risk stratification algorithm selecting patients for prophylactic implantable defibrillators that prevent arrhythmic sudden death; low-risk, high-benefit surgical myectomy to reverse progressive heart failure symptoms due to left ventricula...
Source: Annual Review of Medicine - January 27, 2022 Category: General Medicine Authors: Barry J Maron Ethan J Rowin Martin S Maron Source Type: research

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