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Condition: Atrial Fibrillation
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Total 621 results found since Jan 2013.

Atorvastatin and the influence on postoperative atrial fibrillation after surgical aortic valve replacement (STARC) in adults at Odense University Hospital, Denmark: study protocol for a randomised controlled trial
Introduction Atrial fibrillation (AF) is the most common postoperative complication after surgical aortic valve replacement (SAVR) and occurs in up to 50% of the patients. Development of postoperative AF (POAF) is associated with a 2–3 fold increased risk of adverse events, including stroke, myocardial infarction and death. Several studies have implied that prophylactic Atorvastatin therapy could prevent POAF in patients undergoing coronary artery bypass graft. These studies suggest that Atorvastatin has rapid and significant pleiotropic actions that reduce the risk of POAF. However, prophylactic treatment with stati...
Source: BMJ Open - May 10, 2023 Category: General Medicine Authors: Krasniqi, L., Brandes, A., Mortensen, P. E., Dahl, J. S., Gerke, O., Ali, M., Riber, L. P. S. Tags: Open access, Cardiovascular medicine Source Type: research

P-wave terminal force in lead V1 and atrial fibrillation burden in cryptogenic stroke with implantable loop recorders
AbstractImplantable loop recorders (ILRs) are useful for the detection of atrial fibrillation (AF) in patients with cryptogenic stroke (CS). P-wave terminal force in lead V1 (PTFV1) is associated with AF detection; however, data on the association between PTFV1 and AF detection using ILRs in patients with CS are limited. Consecutive patients with CS with implanted ILRs from September 2016 to September 2020 at eight hospitals in Japan were studied. PTFV1 was calculated by 12-lead ECG before ILRs implantation. An abnormal PTFV1 was defined as  ≥ 4.0 mV × ms. The AF burden was calculated as a proportion based on t...
Source: Journal of Thrombosis and Thrombolysis - May 2, 2023 Category: Hematology Source Type: research

A New Study Shows How Seriously Air Pollution Can Affect Your Heartbeat
For China’s 1.4 billion people, the simple act of breathing has long been something of a risk. Living in the ninth-dirtiest country in the world in terms of air quality, China’s residents lose an average of 2.6 years of life per capita due to atmospheric pollution alone. The greatest risk, of course, is pulmonary, with air pollution leading to shortness of breath, wheezing, coughing, asthma episodes, and chest pain. But pollution affects the heart too; the U.S. Environmental Protection Agency reports that exposure to fine-particulate matter as well as to nitrogen oxides alone can lead to premature aging in bloo...
Source: TIME: Health - May 1, 2023 Category: Consumer Health News Authors: Jeffrey Kluger Tags: Uncategorized climate change Climate Is Everything Environment healthscienceclimate Source Type: news

A Simplified Risk Score to Predict In-Hospital Newly-Diagnosed Atrial Fibrillation in Acute Ischemic Stroke Patients
Source: International Journal of General Medicine - April 18, 2023 Category: General Medicine Tags: International Journal of General Medicine Source Type: research

Impact of Frailty on In-Hospital Outcomes in Patients Who Underwent Percutaneous Left Atrial Appendage Occlusion
In patients with atrial fibrillation, frailty is associated with an increased risk of bleeding, especially if patients take oral anticoagulation for stroke prophylaxis.1 Left atrial appendage occlusion (LAAO) is an alternative in patients unable to tolerate anticoagulation. However, whether patients who are frail are more vulnerable to procedural complications associated with LAAO remains undefined.2 We therefore examined in-hospital outcomes in patients who undergo LAAO procedures using a nationally representative real-world cohort of patients.
Source: The American Journal of Cardiology - April 9, 2023 Category: Cardiology Authors: Siddharth Agarwal, Muhammad Bilal Munir, Agam Bansal, Christopher V. DeSimone, Usman Baber, Abhishek Deshmukh, Zain Ul Abideen Asad Source Type: research

Air Pollution and Arrhythmias
Can J Cardiol. 2023 Apr 4:S0828-282X(23)00293-3. doi: 10.1016/j.cjca.2023.03.023. Online ahead of print.ABSTRACTAir pollution is commonly defined as the contamination of the air we breathe by any chemical, physical or biological agent that is potentially threatening to human and ecosystem health. The common pollutants known to be disease-causing are particulate matter, ground-level ozone, sulphur dioxide, nitrogen dioxide and carbon monoxide. Although the association between increasing concentrations of these pollutants and cardiovascular disease is now accepted, the association of air pollution and arrhythmias is less wel...
Source: Atherosclerosis - April 6, 2023 Category: Cardiology Authors: Matthew Bennett Isabelle Nault Michael Koehle Stephen Wilton Source Type: research

Stroke in Atrial Fibrillation and Other Atrial Dysrhythmias
AbstractPurpose of ReviewAtrial fibrillation (AF) is a major risk factor for systemic embolism and ischaemic stroke. Furthermore, AF-related strokes are associated with higher mortality, greater disability, longer hospital stays and lower rates of hospital discharge than strokes caused by other reasons. The aim of this review to summarise the existing evidence on the association of AF with ischemic stroke and provide insights on the pathophysiological mechanisms and the clinical management of patients with AF in order to reduce the burden of ischemic stroke.Recent FindingsBeyond Virchow ’s triad, several pathophysiologic...
Source: Current Cardiology Reports - March 28, 2023 Category: Cardiology Source Type: research

New VOYAGER PAD Analysis Confirms Consistent Benefit of XARELTO ® (rivaroxaban) Plus Aspirin Following Lower Extremity Revascularization (LER)
TITUSVILLE, NJ, March 5, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from a new prespecified analysis from the Phase 3 VOYAGER PAD clinical trial reinforcing the benefits of the XARELTO® (rivaroxaban) vascular dose (2.5 mg twice daily plus aspirin 100 mg once daily) over standard of care (aspirin alone), demonstrating consistent benefit at 30 days, 90 days and up to three years following LER in patients with PAD. Lower extremity revascularization, also called peripheral revascularization, is a procedure that restores blood flow in blocked arteries or veins. This analysis of ...
Source: Johnson and Johnson - March 5, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

Stroke profile and care during the COVID-19 pandemic: What changed and what did not? A prospective cohort from Joinville, Brazil
This study aims to investigate the impact of COVID-19 pandemic on stroke profile and care in Joinville, Brazil.MethodsA prospective population-based cohort enrolled the first-ever cerebrovascular events in Joinville, Brazil, and a comparative analyzes was conducted between the first 12 months following COVID-19 restrictions (starting March 2020) and the 12 months just before. Patients with transient ischemic attack (TIA) or stroke had their profiles, incidences, subtypes, severity, access to reperfusion therapy, in-hospital stay, complementary investigation, and mortality compared.ResultsThe profiles of TIA/stroke patients...
Source: Frontiers in Neurology - February 16, 2023 Category: Neurology Source Type: research

Failure of Guidelines and Consensus Statements to Recommend Follow-up for Chronic Cardiovascular Conditions
Follow-up of chronic medical conditions affects subsequent outcomes through adherence and early detection of progression of disease. Examples include adherence to anticoagulation therapy improving stroke rates and survival in atrial fibrillation,1 adherence to guideline-directed medical therapy improving survival in heart failure,2,3 and regular clinic follow-up of asymptomatic aortic stenosis identifying the optimal time for valve replacement.4,5 While close follow-up of chronic cardiac conditions can improve outcomes,6 and lack of follow-up is a barrier to medication adherence,7 we have observed that practitioners in our...
Source: Heart and Lung - February 16, 2023 Category: Intensive Care Authors: Krishna Patel, Camila M. Maestas, Oksana Petrechko, Himabindu Boja, James C. Blankenship Source Type: research

Registry for Evaluating Healthy Life Expectancy and Long-Term Outcomes after Catheter Ablation of Atrial Fibrillation in the Very Elderly (REHEALTH AF) study: rationale and design of a prospective, multicentre, observational, comparative study
Introduction Data are lacking on the extent to which patients with non-valvular atrial fibrillation (AF) who are aged ≥80 years benefit from ablation treatment. The question pertains especially to patients’ postablation quality of life (QoL) and long-term clinical outcomes. Methods and analysis We are initiating a prospective, registry-based, multicentre observational study that will include patients aged ≥80 years with non-valvular AF who choose to undergo treatment by catheter ablation and, for comparison, such patients who do not choose to undergo ablation (either according to their physician’s advice...
Source: BMJ Open - February 15, 2023 Category: General Medicine Authors: Okumura, Y., Nagashima, K., Watanabe, R., Yokoyama, K., Kato, T., Fukaya, H., Hayashi, H., Nakahara, S., Shimizu, W., Iwasaki, Y.-k., Fujimoto, Y., Mukai, Y., Ejima, K., Otsuka, T., Suzuki, S., Murakami, M., Kimura, M., Harada, M., Koyama, J., Okamatsu, H Tags: Open access, Cardiovascular medicine Source Type: research

Association of Frailty Status on the Causes and Outcomes of Patients Admitted With Cardiovascular Disease
Data are limited about the contemporary association between frailty and the causes and outcomes of patients admitted with cardiovascular diseases (CVD). Using the US National Inpatient Sample, CVD admissions of interest (acute myocardial infarction, ischemic stroke, atrial fibrillation (AF), heart failure, pulmonary embolism, cardiac arrest, and hemorrhagic stroke) were stratified by Hospital Frailty Risk Score (HFRS). Logistic regression was used to determine adjusted odds ratios (aORs) and 95% confidence intervals (CIs) of in-hospital mortality among different groups with frailty.
Source: The American Journal of Cardiology - January 24, 2023 Category: Cardiology Authors: Balamrit Singh Sokhal, Andrija Mateti ć, Muhammad Rashid, Jo Protheroe, Richard Partington, Christian Mallen, Mamas A. Mamas Source Type: research

Reduced dose direct oral anticoagulants compared with warfarin with high time in therapeutic range in nonvalvular atrial fibrillation
The objective of this study was to compare effectiveness and safety between reduced dose DOACs and high TTR warfarin treatment (TTR  ≥ 70%) in NVAF. A Swedish anticoagulation registry was used in identifying eligible patients from July 2011 to December 2017. The study cohort consisted of 40,564 patients with newly initiated DOAC (apixaban, dabigatran, or rivaroxaban) (11,083 patients) or warfarin treatment (29,481 patients ) after exclusion of 374,135 patients due to not being warfarin or DOAC naïve, not being prescribed reduced dose, having previous mechanical heart valve (MHV), or being under 18 years old. The me...
Source: Journal of Thrombosis and Thrombolysis - January 6, 2023 Category: Hematology Source Type: research

Morbid Obesity is Associated with Increased Procedural Complications and Worse In-Hospital Outcomes after Percutaneous Left Atrial Appendage Occlusion Device Implantation
Obesity has adverse effects on cardiovascular hemodynamics and is an independent risk factor for the induction and perpetuation of atrial fibrillation (AF) (1). Percutaneous left atrial appendage occlusion (LAAO) has shown promising results in reducing stroke risk in select AF patients who cannot be managed with a conventional long-term oral anticoagulation strategy (2). In the landmark PROTECT-AF trial evaluating the efficacy and safety of percutaneous LAAO, patients receiving LAAO device had a mean BMI of 31.6 kg/m2 (2), however, no distinct assessment of outcomes were conducted based on body weight.
Source: Heart Rhythm - December 26, 2022 Category: Cardiology Authors: Siddharth Agarwal, Zain Ul Abideen Asad, Muhammad Zia Khan, Lydia Fekadu Messele, Douglas Darden, Deepak Kumar Pasupula, Gagan D. Singh, Uma N. Srivatsa, Salman Zahid, Sudarshan Balla, Christopher V. DeSimone, Abhishek Deshmukh, Muhammad Bilal Munir Source Type: research