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Relationship between left atrial appendage morphology and stroke in patients with atrial fibrillation
Background: Atrial fibrillation (AF) is an important cause of stroke. Given the morbidity and mortality associated with stroke, the risk stratification of patients based on left atrial appendage (LAA) characteristics is of great interest.Objective: To explore the association between LAA morphology and LAA characteristics including the extent of trabeculations, orifice diameter, and length with prevalent stroke in a large cohort of patients with drug refractory AF who underwent AF ablation to develop mechanistic insight regarding the risk of stroke.Methods: An institutional cohort of 1063 patients referred for AF ablation f...
Source: Heart Rhythm - September 27, 2013 Category: Cardiology Authors: Irfan M. Khurram, Jane Dewire, Michael Mager, Farhan Maqbool, Stefan L. Zimmerman, Vadim Zipunnikov, Roy Beinart, Joseph E. Marine, David D. Spragg, Ronald D. Berger, Hiroshi Ashikaga, Saman Nazarian, Hugh Calkins Tags: Atrial Fibrillation Source Type: research

Left atrial appendage morphology in patients with atrial fibrillation in China: implications for stroke risk assessment from a single center study.
CONCLUSION: LAA analysis can potentially be used to inform guidance on the implication for stroke risk assessment. PMID: 25533823 [PubMed - in process]
Source: Chinese Medical Journal - December 1, 2014 Category: Journals (General) Authors: Kong B, Liu Y, Hu H, Wang L, Fan Y, Mei Y, Liu W, Liao J, Liu D, Xing D, Huang H Tags: Chin Med J (Engl) Source Type: research

Atrial Fibrillation and Resistant Stroke: Does Left Atrial Appendage Morphology Matter? A Case Report
Conclusion: The systematic study of LAA in patients with resistant-stroke could help to identify LAA malignant morphology. The efficacy on stroke recurrence of the combined therapy (anticoagulants plus LAAO) is worthy to be tested in randomized trials.
Source: Frontiers in Neurology - November 12, 2020 Category: Neurology Source Type: research

Anatomical characteristics of the left atrial appendage in cardiogenic stroke with low CHADS2 scores
Conclusions: The LAA anatomy might be useful for predicting strokes in patients with nonvalvular AF who have low CHADS2 scores.
Source: Heart Rhythm - February 4, 2013 Category: Cardiology Authors: Takehiro Kimura, Seiji Takatsuki, Kohei Inagawa, Yoshinori Katsumata, Takahiko Nishiyama, Nobuhiro Nishiyama, Kotaro Fukumoto, Yoshiyasu Aizawa, Yoko Tanimoto, Kojiro Tanimoto, Masahiro Jinzaki, Keiichi Fukuda Tags: Creative Concepts Source Type: research

Left Atrial Appendage Morphology by CT; AF Stroke RiskLeft Atrial Appendage Morphology by CT; AF Stroke Risk
Of four left-atrial-appendage morphology types by CT imaging, which had colorful names like "cauliflower" and "chicken wing," one independently predicted stroke in patients with atrial fibrillation but a low CHADS2 score. Heartwire
Source: Medscape Today Headlines - February 26, 2013 Category: Consumer Health News Tags: Cardiology News Source Type: news

Cruciferous LAA predicts stroke in otherwise-low-risk AF patients
Of four left-atrial-appendage morphology types by CT imaging, which had colorful names like "cauliflower" and "chicken wing," one independently predicted stroke in patients with atrial fibrillation but a low CHADS2 score.
Source: theHeart.org - February 25, 2013 Category: Cardiology Source Type: news

Relations between left atrial appendage contrast retention and thromboembolic risk in patients with atrial fibrillation
This study was designed to assess the relations between LAA contrast retention and thrombogenesis risk of the LAA in patients with non-valvular atrial fibrillation. A total of 132 consecutive patients who underwent LAAO were enrolled. The data collected from computed tomography (CT), transthoracic echocardiography (TTE), transesophageal echocardiography (TEE) and blood samples were analyzed. Univariate and multivariate logistic regression models were constructed to assess the association between CR, left atrial appendage thrombus (LAAT) and other factors. Contrast retention was observed in 33 patients, accounting for 25% o...
Source: Journal of Thrombosis and Thrombolysis - June 15, 2021 Category: Hematology Source Type: research

Cardiogenic Stroke despite Low CHA2DS2‐VASc Score: Assessing Stroke risK by Left Atrial Appendage Anatomy (ASK LAA)
Conclusion: A higher LAA takeoff is associated with a tachycardia‐mediated thrombogenic flow and an increased thromboembolic risk. These findings may have implications for anticoagulation management of AF patients with low CHA2DS2‐VASc scores and higher LAA takeoff.This article is protected by copyright. All rights reserved
Source: Journal of Cardiovascular Electrophysiology - July 14, 2015 Category: Cardiology Authors: Sotirios Nedios, Emmanuel Koutalas, Jelena Kornej, Sascha Rolf, Arash Arya, Philipp Sommer, Daniela Husser, Gerhard Hindricks, Andreas Bollmann Tags: Original Source Type: research

Correlation between left atrial appendage morphology and flow velocity in patients with paroxysmal atrial fibrillation
Conclusion LAA morphology is a significant determinant of LAAFV, suggesting an underlying mechanism for the association between LAA morphology and embolic events.
Source: European Journal of Echocardiography - December 18, 2015 Category: Cardiology Authors: Fukushima, K., Fukushima, N., Kato, K., Ejima, K., Sato, H., Fukushima, K., Saito, C., Hayashi, K., Arai, K., Manaka, T., Ashihara, K., Shoda, M., Hagiwara, N. Tags: ORIGINAL ARTICLES Source Type: research

A Morphological Study of Left Atrial Appendage in Egyptian patients Using multidetector computed tomography (MDCT)
ConclusionEgyptian patients had predominantly windsock morphology in males and cactus morphology in females.
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research

Application of computed tomographic angiography and echocardiography in predicting left atrial appendage thrombosis in patients with non-valvular atrial fibrillation
CONCLUSIONS: Both CTA and RT-3D-TEE had high predictive values for LAA thrombosis in atrial fibrillation patients.PMID:36383152 | DOI:10.5830/CVJA-2022-052
Source: Cardiovascular Journal of Africa - November 16, 2022 Category: Cardiology Authors: Xiaodan Wu Fan Sun Shoucheng Ma Zhichen Wang Shenghai Xu Source Type: research

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