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Condition: Atrial Fibrillation
Countries: Denmark Health

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Total 102 results found since Jan 2013.

Using the Case-Crossover Design to Assess Short-Term Risks of Bleeding and Arterial Thromboembolism After Switching Between Oral Anticoagulants in a Population-Based Cohort of Patients With Atrial Fibrillation
AbstractUsing nationwide Danish registries, we conducted a population-based case-crossover study evaluating the association between switching from a vitamin K antagonist (VKA) to a direct oral anticoagulant (DOAC), and vice versa, and 30-day risks of bleeding and arterial thromboembolism in patients with atrial fibrillation (AF). The case-crossover population was identified among oral anticoagulant users during 2011 –2018 (n = 123,217) as patients with AF with 1) a case-defining outcome and 2) an anticoagulant switch during the 180 days preceding the outcome. Odds ratios were estimated using conditional logistic regres...
Source: American Journal of Epidemiology - July 8, 2020 Category: Epidemiology Source Type: research

Treatment patterns for oral anticoagulants in older patients with atrial fibrillation: a retrospective, cross-sectional, nationwide study from Denmark
Conclusion In this large nationwide study, we found that in older patients with AF, the overall rates of OAC prescription were generally high (~80%) and increasing during the last decade. Factors associated with not receiving guideline recommended OAC treatment were generally related to bleeding risk factors or frailty.
Source: BMJ Open - September 1, 2022 Category: General Medicine Authors: Rasmussen, P. V., Sakthivel, T., Dalgaard, F., Gislason, G. H., Pallisgaard, J. L., Hansen, M. L. Tags: Open access, Cardiovascular medicine Source Type: research

Long-term cardiovascular outcomes and temporal trends in patients diagnosed with ANCA-associated vasculitis: a Danish nationwide registry study
ConclusionsPatients with AAV are at increased risk of heart failure, atrial-/ventricular arrhythmias, venous thrombotic events, ischaemic stroke and myocardial infarction. Furthermore, patients with AAV were more frequently examined with coronary procedures and underwent more coronary revascularizations. No temporal changes in ischaemic cardiovascular outcomes were observed, albeit the cardiovascular mortality has decreased over time.
Source: Rheumatology - July 5, 2022 Category: Rheumatology Source Type: research

Temporal changes in patient characteristics and prior pharmacotherapy in patients undergoing radiofrequency ablation of atrial fibrillation: a Danish nationwide cohort study
Conclusion During a 10-year period, RFA was increasingly performed in older patients with higher co-morbidity, and without prior trial of antiarrhythmic therapy. These findings may provide a framework to understand the outcomes of RFA.
Source: Europace - April 26, 2013 Category: Cardiology Authors: Karasoy, D., Gislason, G. H., Hansen, J., Olesen, J. B., Torp-Pedersen, C., Johannessen, A., Hansen, M. L. Tags: Ablation for atrial fibrillation Source Type: research

Shifting to a non-vitamin K antagonist oral anticoagulation agent from vitamin K antagonist in atrial fibrillation
ConclusionIn a contemporary setting among VKA-experienced NVAF patients; VKA is still prevalent although about 30% by December 2015 had shifted to a NOAC.
Source: Europace - June 28, 2017 Category: Cardiology Source Type: research

Duration of hyperthyroidism and lack of sufficient treatment are associated with increased cardiovascular risk.
CONCLUSION: Risk of cardiovascular disease was found increased in untreated hyperthyroid patients, and duration of decreased TSH associated with increasing risk of cardiovascular outcomes in both treated and untreated hyperthyroid individuals. This suggests that increased cardiovascular risk is not only driven by lack of treatment but also by insufficient therapy. Our results support timely treatment and careful monitoring of hyperthyroid patients in order to reduce cardiovascular risk. PMID: 30648498 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - January 18, 2019 Category: Endocrinology Tags: Thyroid Source Type: research

Depression and Uptake of Oral Anticoagulation Therapy in Patients With Atrial Fibrillation: A Danish Nationwide Cohort Study
Conclusions: Comorbid depression was associated with a significantly lower OAT uptake in patients with AF, which questions whether depressed patients receive sufficient support to manage this consequential cardiac condition. However, a substantial increase in the overall OAT uptake and a decrease of the depression-associated deficit in OAT were seen over the period during which OAT was developed through the introduction of new oral anticoagulation therapy.
Source: Medical Care - February 13, 2020 Category: Health Management Tags: Original Articles Source Type: research

Thromboembolic events related to atrial fibrillation during the COVID-19 epidemic in Denmark
The COVID-19 epidemic has threatened to overwhelm the health-care systems of European countries resulting in government decisions of extensive societal lockdowns. There have been considerable concerns regarding the collateral effects of the COVID-19 epidemic overshadowing the care of patients with other medical conditions including cardiovascular diseases. Of interest, decreases in the registered incidences of atrial fibrillation (AF) and ischemic stroke have been reported [1,2]. AF is a common reason for physician contact and AF patients are often recommended treatment with oral anticoagulants to mitigate the associated r...
Source: Thrombosis Research - July 29, 2020 Category: Hematology Authors: Peter Vibe Rasmussen, Paul Blanche, Jarl Emanuel Strange, Jawad Haider Butt, Frederik Dalgaard, Kristian Kragholm, Matthew Phelps, Gunnar Gislason, Morten Lock Hansen Tags: Letter to the Editors-in-Chief Source Type: research

Long ‐term risk of heart failure and mortality following mitral valve surgery in patients with and without right ventricular pacemaker
ConclusionsPostoperative implantation of a permanent RV pacemaker does not alter the long ‐term risks of HF and mortality following mitral valve surgery.
Source: Journal of Cardiac Surgery - September 27, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Charlotte Andersson, Morten Schou, Gunnar H. Gislason, Lars K øber, Christian Torp‐Pedersen, Kevin M. Monahan Tags: ORIGINAL ARTICLE Source Type: research

Discontinuation of oral anticoagulation and risk of stroke and death after ablation for typical atrial flutter: A nation-wide Danish cohort study
Oral anticoagulation (OAC) is indicated for patients with atrial fibrillation (AF) and atrial flutter (AFL) with a CHA2DS2-VASc score  ≥ 2 for men and ≥3 for women. This is regardless of successful catheter ablation for their arrhythmia. Studies have mainly focused on AF, and little is known regarding use of OAC in AFL patients following catheter ablation.
Source: International Journal of Cardiology - February 26, 2021 Category: Cardiology Authors: Mikkel Giehm-Reese, Martin Nyg ård Johansen, Mads Brix Kronborg, Henrik Kjærulf Jensen, Christian Gerdes, Jens Kristensen, Arne Johannessen, Peter Karl Jacobsen, Mogens Stig Djurhuus, Peter Steen Hansen, Sam Riahi, Jens Cosedis Nielsen Source Type: research

Geographical variation and clustering are found in atrial fibrillation beyond socioeconomic differences: a Danish cohort study, 1987 –2015
The prevalence and incidence rate of atrial fibrillation (AF) increase worldwide and AF is a risk factor for more adverse cardiovascular diseases including stroke. Approximately 44% of AF cases cannot be expla...
Source: International Journal of Health Geographics - March 1, 2021 Category: International Medicine & Public Health Authors: Kirstine Wodschow, Kristine Bihrmann, Mogens Lytken Larsen, Gunnar Gislason and Annette Kj ær Ersbøll Tags: Research Source Type: research

Anticoagulation management of postoperative atrial fibrillation after cardiac surgery: A systematic review
ConclusionThere is wide practice variation in the uptake, timing of initiation, duration, and choice of OAC for POAF following cardiac surgery. The evidence is largely retrospective and insufficient to assess the efficacy of different OAC strategies. Further studies are warranted to guide clinical practice.
Source: Journal of Cardiac Surgery - March 27, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Ren Jie R. Yao, Nathaniel M. Hawkins, Yasaman Lavaie, Marc W. Deyell, Jason G. Andrade, Jamil Bashir Tags: REVIEW ARTICLE Source Type: research

All-cause mortality and location of death in patients with established cardiovascular disease before, during, and after the COVID-19 lockdown: a Danish Nationwide Cohort Study
ConclusionsAmong patients with established cardiovascular disease, the in-hospital mortality rate was lower and out-of-hospital mortality rate higher during lockdown compared with the same period in the preceding year, irrespective of age and sex.
Source: European Heart Journal - February 24, 2021 Category: Cardiology Source Type: research

Joint mapping of cardiovascular diseases: comparing the geographic patterns in incident acute myocardial infarction, stroke and atrial fibrillation, a Danish register-based cohort study 2014 –15
Disease mapping aims at identifying geographic patterns in disease. This may provide a better understanding of disease aetiology and risk factors as well as enable targeted prevention and allocation of resourc...
Source: International Journal of Health Geographics - August 30, 2021 Category: International Medicine & Public Health Authors: Kristine Bihrmann, Gunnar Gislason, Mogens Lytken Larsen and Annette Kj ær Ersbøll Tags: Research Source Type: research

Long-term Risk of Heart Failure and Other Adverse Cardiovascular Outcomes in Granulomatosis With Polyangiitis: a Nationwide Cohort Study
CONCLUSION: During the first year after diagnosis, the rates of HF and other cardiovascular outcomes were higher in patients with GPA compared with the background population. However, after the first year, the rates of HF and other cardiovascular outcomes, except atrial fibrillation/flutter, were similar to those in the background population.PMID:34782450 | DOI:10.3899/jrheum.210677
Source: J Rheumatol - November 16, 2021 Category: Rheumatology Authors: Guoli Sun Adelina Yafasova Bo Baslund Mikkel Faurschou Morten Schou Abdulrahman Shams-Eldin S øren Lund Kristensen Peter E Weeke Christian Torp-Pedersen Emil L Fosb øl Lars K øber Jawad H Butt Source Type: research