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Condition: Stroke
Procedure: Anesthesia

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Total 3904 results found since Jan 2013.

Technical improvements in carotid revascularization based on the mechanism of procedural stroke.
In conclusion, this review provides an overview of the pathophysiological mechanism of stroke following carotid revascularization (both CAS and CEA) and of the technical improvements that have contributed to reducing this stroke risk. PMID: 30827087 [PubMed - as supplied by publisher]
Source: The Journal of Cardiovascular Surgery - February 28, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Fassaert LM, de Borst GJ Tags: J Cardiovasc Surg (Torino) Source Type: research

Preoperative Stroke and Outcomes after Coronary Artery Bypass Graft Surgery
Conclusions: The authors found no evidence that more recent preoperative stroke predisposed patients undergoing CABG surgery to suffer postoperative stroke, death, or prolonged length of stay. The combination of prior stroke and myocardial infarction substantially increased perioperative risk.
Source: Anesthesiology - February 20, 2013 Category: Anesthesiology Tags: Perioperative Medicine Source Type: research

Perioperative Metoprolol and Risk of Stroke after Noncardiac Surgery
Background: Numerous risk factors have been identified for perioperative stroke, but there are conflicting data regarding the role of β adrenergic receptor blockade in general and metoprolol in particular. Methods: The authors retrospectively screened 57,218 consecutive patients for radiologic evidence of stroke within 30 days after noncardiac procedures at a tertiary care university hospital. Incidence of perioperative stroke within 30 days of surgery and associated risk factors were assessed. Patients taking either metoprolol or atenolol were matched based on a number of risk factors for stroke. Parsimonious logistic re...
Source: Anesthesiology - November 19, 2013 Category: Anesthesiology Tags: Perioperative Medicine Source Type: research

The Association Between Mild Intraoperative Hypotension and Stroke in General Surgery Patients.
CONCLUSIONS: In our propensity score-matched case-control study, we did not find an association between intraoperative hypotension, defined as MAP < 70 mm Hg, and postoperative stroke. PMID: 27636576 [PubMed - in process]
Source: Anesthesia and Analgesia - September 19, 2016 Category: Anesthesiology Authors: Hsieh JK, Dalton JE, Yang D, Farag ES, Sessler DI, Kurz AM Tags: Anesth Analg Source Type: research

Perioperative Low Arterial Oxygenation Is Associated With Increased Stroke Risk in Cardiac Surgery.
CONCLUSIONS: Odds of stroke after cardiac surgery are increased in patients with a low minimum PaO2 within 24 hours of surgery. Results should be validated in an independent cohort. Further characterizing the underlying etiology of hypoxic episodes will be important to improve patient outcomes. PMID: 28614129 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - June 12, 2017 Category: Anesthesiology Authors: Dunham AM, Grega MA, Brown CH, McKhann GM, Baumgartner WA, Gottesman RF Tags: Anesth Analg Source Type: research

Defining an Intraoperative Hypotension Threshold in Association with Stroke in Cardiac Surgery
Conclusions Hypotension is a potentially modifiable risk factor for perioperative stroke. The study ’s findings suggest that mean arterial pressure may be an important intraoperative therapeutic hemodynamic target to reduce the incidence of stroke in patients undergoing cardiopulmonary bypass.
Source: Anesthesiology - August 14, 2018 Category: Anesthesiology Source Type: research

Knowledge and perceptions about perioperative stroke: a cross-sectional survey of patients scheduled for non-neurologic and non-cardiac surgery.
CONCLUSIONS: Patients at higher risk of stroke frequently underestimate their risk of perioperative stroke. The majority of patients had not discussed perioperative stroke prior to anesthetic consultation. PMID: 31531829 [PubMed - as supplied by publisher]
Source: Canadian Journal of Anaesthesia - September 16, 2019 Category: Anesthesiology Authors: Roughead T, Chui J, Gelb AW, Meng L, Sewell D, Flexman AM Tags: Can J Anaesth Source Type: research

Clinical Response to Procedural Stroke Following Carotid Endarterectomy: A  Delphi Consensus Study
CONCLUSION: In patients having a stroke following carotid endarterectomy, expedited diagnostics should be performed initially in most phases. In patients who experience an ipsilateral intra-operative stroke following carotid clamp release, immediate re-exploration of the index carotid artery is recommended.PMID:34312072 | DOI:10.1016/j.ejvs.2021.05.033
Source: PubMed: Eur J Vasc Endovasc ... - July 27, 2021 Category: Surgery Authors: Armelle J A Meershoek Djurre D de Waard Jaap Trappenburg Clark J Zeebregts Richard Bulbulia Jaap L J Kappelle Gert-Jan de Borst Delphi consensus experts panel Source Type: research

Neurological scoring and gait kinematics to assess functional outcome in an ovine model of ischaemic stroke
ConclusionThis study developed repeatable methods to assess function in sheep using composite scoring and gait kinematics, allowing for the evaluation of deficit 3 days post-stroke. Despite utility of each method independently, there was poor association observed between gait kinematics, composite scoring, and infarct volume on PCA. This suggests that each of these measures has discreet utility for the assessment of stroke deficit, and that multimodal approaches are necessary to comprehensively characterise functional impairment.
Source: Frontiers in Neurology - February 20, 2023 Category: Neurology Source Type: research

Improving the translation of animal ischemic stroke studies to humans
Abstract Despite testing more than 1,026 therapeutic strategies in models of ischemic stroke and 114 therapies in human ischemic stroke, only one agent tissue plasminogen activator has successfully been translated to clinical practice as a treatment for acute stroke. Though disappointing, this immense body of work has led to a rethinking of animal stroke models and how to better translate therapies to patients with ischemic stroke. Several recommendations have been made, including the STAIR recommendations and statements of RIGOR from the NIH/NINDS. In this commentary we discuss additional aspects that may be imp...
Source: Metabolic Brain Disease - March 6, 2015 Category: Neurology Source Type: research

Covert stroke after non-cardiac surgery: a prospective cohort study
Conclusions This international multicentre study suggests that 1 in 10 patients ≥65 yr of age experiences a perioperative covert stroke. A larger study is required to determine the impact of perioperative covert stroke on patient-important outcomes. Clinical trial registration NCT01369537.
Source: British Journal of Anaesthesia - July 19, 2016 Category: Anesthesiology Authors: Mrkobrada, M., Hill, M. D., Chan, M. T. V., Sigamani, A., Cowan, D., Kurz, A., Sessler, D. I., Jacka, M., Graham, M., Dasgupta, M., Dunlop, V., Emery, D. J., Gulka, I., Guyatt, G., Heels-Ansdell, D., Murkin, J., Pettit, S., Sahlas, D. J., Sharma, M., Shar Tags: Clinical Practice Source Type: research

Knowledge and perceptions about perioperative stroke: a cross-sectional survey of patients scheduled for non-neurologic and non-cardiac surgery
ConclusionsPatients at higher risk of stroke frequently underestimate their risk of perioperative stroke. The majority of patients had not discussed perioperative stroke prior to anesthetic consultation.
Source: Canadian Journal of Anesthesia - December 17, 2019 Category: Anesthesiology Source Type: research

Intraoperative hypotension and perioperative acute ischemic stroke in patients having major elective non-cardiovascular non-neurological surgery
ConclusionOur analysis suggests that when MAP is less than 60  mmHg for more than 20 min, there is increased odds of acute ischemic stroke. Further studies are needed to determine what MAP should be targeted during surgery to optimize cerebral perfusion and limit ischemic stroke risk.
Source: Journal of Anesthesia - February 9, 2021 Category: Anesthesiology Source Type: research

Type of anaesthesia for acute ischaemic stroke endovascular treatment
CONCLUSIONS: In early outcomes, general anaesthesia improves target artery revascularisation compared to non-general anaesthesia with moderate-certainty evidence. General anaesthesia may improve adverse events (haemodynamic instability) compared to non-general anaesthesia with low-certainty evidence. We found no evidence of a difference in neurological impairment, stroke-related mortality, all intracranial haemorrhage and haemodynamic instability adverse events between groups with low-certainty evidence. We are uncertain whether general anaesthesia improves functional outcomes and time to revascularisation because the cert...
Source: Cochrane Database of Systematic Reviews - July 20, 2022 Category: General Medicine Authors: Renato Tosello Rachel Riera Giuliano Tosello Caroline Nb Clezar Jorge E Amorim Vladimir Vasconcelos Benedito B Joao Ronald Lg Flumignan Source Type: research