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Condition: Stroke
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Total 908 results found since Jan 2013.

Differences in Ischaemic and Haemorrhagic Strokes in Sri Lanka: 7-year data from the Ragama Stroke Registry (P1.092)
CONCLUSIONS:Clinical and risk factor profiles were different between ICH and IS patients. Stroke severity and functional disability were higher among ICH patients. Study Supported by:Ragama Stroke Registry has been partly supported by research grants from the University of Kelaniya and Research Institute, International Medical Centre of Japan.Disclosure: Dr. Ranawaka has nothing to disclose. Dr. Peiris has nothing to disclose. Dr. Thirumavalavan has nothing to disclose. Dr. Premawansa has nothing to disclose. Dr. Kasthuriratne has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ranawaka, U., Peiris, A., Thirumavalavan, K., Premawansa, G., Kasthuriratne, A. Tags: Neuroepidemiology: Cerebrovascular Disease, Critical Care, Epilepsy, Child Neurology, and Sleep Source Type: research

Fasting Serum Apolipoprotein B48 Is a Risk Factor for Large Artery Atherosclerotic Stroke (P5.233)
Conclusions: We have found an association between high apolipoprotein B48 levels and ischemic stroke, and in particular large artery atherosclerotic stroke. Study supported by a grant from Health Department of Sichuan Province (No.110570)Disclosure: Dr. yong has nothing to disclose. Dr. Ping has nothing to disclose. Dr. Chun has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Yong, C., Ping, L., Chun, W. Tags: Cerebrovascular Disease: Biomarkers Source Type: research

Circulating leukocytes perpetuate stroke ‐induced aortic dysfunction
This article is protected by copyright. All rights reserved
Source: Experimental Physiology - July 1, 2017 Category: Physiology Authors: Shinichi Asano, Grant C. O'Connell, Kent C. Lemaster, Evan R. DeVallance, Kayla W. Branyan, James W. Simpkins, Jefferson C. Frisbee, Taura L. Barr, Paul D. Chantler Tags: Research Paper Source Type: research

Mediterranean diet cuts heart and stroke risk
Conclusion The results of this randomised controlled trial appear to confirm previous studies that there are benefits to following a Mediterranean diet. The trial has many strengths, including its large size, long period of follow-up, thorough assessment of medical outcomes (including reviewing medical records and having contact with the family doctor), and careful attempts to assess whether the diets were being followed. As this is a randomised controlled trial, it should also balance out other health and lifestyle differences between the groups that may influence cardiovascular risk. This avoids the limitations of m...
Source: NHS News Feed - February 26, 2013 Category: Consumer Health News Tags: Food/diet Heart/lungs Source Type: news

UCLA brain-imaging tool and stroke risk test help identify cognitive decline early
UCLA researchers have used a brain-imaging tool and stroke risk assessment to identify signs of cognitive decline early on in individuals who don't yet show symptoms of dementia.   The connection between stroke risk and cognitive decline has been well established by previous research. Individuals with higher stroke risk, as measured by factors like high blood pressure, have traditionally performed worse on tests of memory, attention and abstract reasoning.   The current small study demonstrated that not only stroke risk, but also the burden of plaques and tangles, as measured by a UCLA brain scan, may influence c...
Source: UCLA Newsroom: Health Sciences - April 3, 2013 Category: Universities & Medical Training Source Type: news

Quality of life in stroke survivor–caregiver dyads: a new conceptual framework and longitudinal study protocol
This study seeks to identify variables in the pre‐existing situation prior to the stroke (e.g. living condition), the new situation mediation poststroke (e.g. type of stroke and caregiver burden) as well as situation moderators (e.g. social support) that influence stroke survivor‐caregiver dyad's quality of life across the stroke trajectory. Also, the study will inform clinical practice and research by identifying variables that are potentially modifiable and therefore amenable to intervention. The proposed framework will also be helpful for future research focused on stroke survivor–caregiver dyads.
Source: Journal of Advanced Nursing - September 1, 2014 Category: Nursing Authors: Serenella Savini, Harleah G. Buck, Victoria Vaughan Dickson, Silvio Simeone, Gianluca Pucciarelli, Roberta Fida, Maria Matarese, Rosaria Alvaro, Ercole Vellone Tags: Protocol Source Type: research

Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial
Publication date: Available online 6 February 2019Source: The LancetAuthor(s): Philip M Bath, Polly Scutt, Craig S Anderson, Jason P Appleton, Evind Berge, Lesley Cala, Mark Dixon, Timothy M England, Peter J Godolphin, Diane Havard, Lee Haywood, Trish Hepburn, Kailash Krishnan, Grant Mair, Alan A Montgomery, Keith Muir, Stephen J Phillips, Stuart Pocock, John Potter, Chris PriceSummaryBackgroundHigh blood pressure is common in acute stroke and is a predictor of poor outcome; however, large trials of lowering blood pressure have given variable results, and the management of high blood pressure in ultra-acute stroke remains ...
Source: The Lancet - February 7, 2019 Category: General Medicine Source Type: research

E-013 unchanged utilization of endovascular treatment in acute ischemic stroke patients in the post ims-iii era
ConclusionContrary to expectations, there has been no reduction in the utilization of endovascular treatment among acute ischemic stroke patients after IMS-III, MR RESCUE and SYNTHESIS EXPANSION results were published.Abstract E-013 Table 1Pre and Post IMS III Pre-IMS III Post-IMS III P-value Patients with ischemic stroke (%)6765 (50.5)6643 (49.5)Mechanical thrombectomy155 (2.3)161 (2.4)0.6IV tPA483 (7.1)520 (7.8)0.1Discharge dispositionHome or self care3135 (46.6)3079 (46.3)Skilled nursing facility1529 (22.6)1486 (22.4)Expired268 (4.0)253 (3.8)0.3Length of stay in hospital3.8 ± 4.13.6 ± 3.50.02Hospital c...
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Hassan, A., Bezzina, C., Malik, A., Sanchez, C., Tekle, W., Qureshi, A. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

Carotid Intima-Media Thickness, but neither Framingham Risk Score nor Omnibus Risk Score, is associated with stroke among Nigerian African hypertensive patients (P2.269)
Conclusion: CIMT, but neither FRS nor ORS, is significantly and independently associated with stroke among Nigerian African hypertensive patients. CIMT appears to be a better indicator of stroke than FRS or ORS in this population. Study Partially Supported by:Mac Arthur Grant, University of IbadanDisclosure: Dr. Owolabi has nothing to disclose. Dr. Akpa has nothing to disclose. Dr. Agunloye has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Owolabi, M., Akpa, O., Agunloye, A. Tags: Cerebrovascular Disease and Interventional Neurology: Carotid Disease and IMT Source Type: research

COLADAS: Caribbean Origin Latin Americans Disparities in Acute Stroke (I5.006)
Conclusions: Our study reveals intrinsic sex differences that may imply under treatment. Understanding the reasons underlying these "sex-gaps" is critical. Study Supported By: Award Number Grants 5S21MD000242 and 5S21MD000138, from the National Center for Minority Health and Health Disparities, National Institutes of Health (NCMHD-NIH).Disclosure: Dr. Teron Molina has nothing to disclose. Dr. Rodríguez Centeno has nothing to disclose. Dr. Santiago has nothing to disclose. Dr. López Valentín has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Teron Molina, I., Rodriguez Centeno, A., Santiago, F., Lopez Valentin, M. Tags: Sex-related Factors in Neurological Disease Data Blitz Presentations Source Type: research

Cerebrolysin for acute ischaemic stroke.
CONCLUSIONS: The findings of this Cochrane Review do not demonstrate clinical benefits of cerebrolysin for treating acute ischaemic stroke. We found moderate-quality evidence suggesting that serious adverse events may be more common with cerebrolysin use in acute ischaemic stroke. PMID: 27918088 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - December 4, 2016 Category: Journals (General) Authors: Ziganshina LE, Abakumova T, Vernay L Tags: Cochrane Database Syst Rev Source Type: research

The Taking Charge After Stroke (TaCAS) study protocol: a multicentre, investigator-blinded, randomised controlled trial comparing the effect of a single Take Charge session, two Take Charge sessions and control intervention on health-related quality of life 12 months after stroke for non-Maori, non-Pacific adult New Zealanders discharged to community living
Introduction Stroke is one of the leading causes of disability worldwide. Recent data support the possibility that person-centred, self-management interventions can reduce dependence after stroke. However, there is limited information on the generalisability and optimum dose of these interventions. Methods The Taking Charge After Stroke (TaCAS) study is a multicentre, investigator-blinded, randomised controlled trial recruiting 400 participants following acute stroke from seven hospitals in New Zealand. All patients discharged to community living who have ongoing symptoms at time of discharge (modified Rankin scale>0) ...
Source: BMJ Open - June 1, 2017 Category: General Medicine Authors: Fu, V. W. Y., Weatherall, M., McNaughton, H. Tags: Open access, Rehabilitation medicine Protocol Source Type: research

Patients experience of and participation in a stroke self-management programme, My Life After Stroke (MLAS): a multimethod study
Conclusions MLAS was a positive experience for participants but many stroke survivors did not feel it was appropriate for them. Participation in self-management programmes after stroke might be improved by offering them sooner after the stroke and providing a range of delivery options beyond group-based, face-to-face learning. Trial registration number NCT03353519, NIH.
Source: BMJ Open - November 15, 2022 Category: General Medicine Authors: Blatchford, E. G., Aquino, M. R. J., Grant, J., Johnson, V., Mullis, R., Lim, L., Mant, J. Tags: Open access, Public health Source Type: research

Diurnal Distribution of Patients Presenting at the Emergency Department with Acute Ischemic Stroke and Its Impact on Functional Outcome (P03.196)
CONCLUSIONS: A distinct diurnal pattern of ED arrival for acute ischemic stroke is observed with peak attendance in late morning. This was not associated with poorer functional outcome.Supported by: SingHealth Foundation Grant, National Neuroscience Institute, Singapore Health Services Pte Ltd.Disclosure: Dr. Tu has nothing to disclose. Dr. Tin has nothing to disclose. Dr. Oh has nothing to disclose. Dr. En has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Tu, T. M., Tin, A. S., Oh, H. C., En, L. Tags: P03 Cerebrovascular Disease III Source Type: research

Homoarginine Levels are Regulated by L-Arginine:Glycine Amidinotransferase and Affect Stroke Outcome: Results from Human and Murine Studies.
CONCLUSIONS: Low homoarginine appears related to poor outcome after ischemic stroke. Further validation in future trials may lead to therapeutic adjustments of homoarginine metabolism that alleviate stroke and other vascular disorders. PMID: 24004504 [PubMed - as supplied by publisher]
Source: Circulation - September 4, 2013 Category: Cardiology Authors: Choe CU, Atzler D, Wild PS, Carter AM, Böger RH, Ojeda F, Simova O, Stockebrand M, Lackner K, Nabuurs C, Marescau B, Streichert T, Müller C, Lüneburg N, De Deyn PP, Benndorf RA, Baldus S, Gerloff C, Blankenberg S, Heerschap A, Grant PJ, Magnus T, Zelle Tags: Circulation Source Type: research