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Age Is a Greater Influence on Small Saccades Than Target Size in Normal Subjects on the Horizontal Video Head Impulse Test
Conclusion: While this study suggests that target size may have a statistically significant impact on the vHIT saccade profile of normal subjects, age has a greater influence on the incidence and size of small vHIT saccades.
Introduction
The video head impulse test (vHIT) is a quantitative adaptation of the clinical head impulse test (1), and enables functional assessment of the high-frequency angular vestibulo-ocular reflex (VOR) in all three planes of head rotation (2, 3). Lightweight goggles worn by the subject detect head movement using an accelerometer and gyroscope, and a high frame rate video camera tracks eye...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research
Cochrane ' s 30 under 30: Ndi Euphrasia Ebai-Atuh
Cochrane is made up of 13,000 members and over 50,000 supporters come from more than 130 countries, worldwide. Our volunteers and contributors are researchers, health professionals, patients, carers, people passionate about improving health outcomes for everyone, everywhere.Cochrane is an incredible community of people who all play their part in improving health and healthcare globally. We believe that by putting trusted evidence at the heart of health decisions we can achieve a world of improved health for all. Many of our contributors are young people working with Cochrane as researchers, citizen scientists...
Source: Cochrane News and Events - April 12, 2019 Category: Information Technology Authors: Lydia Parsonson Source Type: news
Sickle Cell Disease Subjects Have a Distinct Abnormal Autonomic Phenotype Characterized by Peripheral Vasoconstriction With Blunted Cardiac Response to Head-Up Tilt
Conclusion
We have shown that SCD subjects are much more likely than non-SCD subjects to have impaired cardiac, but intact peripheral responses to orthostatic stress induced by HUT. These abnormal responses are associated with low baseline cardiac parasympathetic activity, independent of hemoglobin level. The classification of autonomic phenotypes based on HUT response may have potential use for predicting disease severity, guiding and targeting treatments/interventions to alleviate the risk of adverse outcomes in SCD.
Ethics Statement
All experiments were conducted at Children’s Hospital Los Angeles (CHLA). The ...
Source: Frontiers in Physiology - April 10, 2019 Category: Physiology Source Type: research
Fool Me Once: An Uncommon Presentation of PE
BY FREDDIE IRIZARRY-DELGADO; VAROON KAKAIYA; & AHMED RAZIUDDIN, MDAn 86-year-old African-American woman was brought to the ED by her daughter after two days of nutritional neglect, abdominal pain, and altered mental status. Her daughter said her mother felt lightheaded, appeared dehydrated, and vomited nonbilious watery fluid once. The patient had a history of diabetes mellitus type 2, DVT/PE, dementia, and early signs of parkinsonism.Her vital signs were remarkable only for tachypnea (24 bpm). Her troponin I was markedly elevated at 1.7 ng/mL. A D-dimer was ordered because of her history of unprovoked DVT/PE, and i...
Source: The Case Files - November 27, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: research
“His Entire Body Was Shutting Down”: New State Rankings Show Gaps in High School Athlete Safety
By mid-afternoon on August 1, 2017, the temperature in Stockton, Calif. was at least 105 degrees. Thirteen-year-old Jayden Galbert complained to his mother, Shynelle Jones, about the heat, but didn’t want to skip preseason football practice and hurt his chances of making the freshman football team. Instead, he showed up, pushed himself to participate, and then collapsed on the field. “He started vomiting and he was shaking,” Jones says. “He couldn’t see. He was trying to focus, but he couldn’t.” Jayden was eventually airlifted to UC Davis Medical Center, where he was diagnosed with...
Source: TIME: Health - August 22, 2018 Category: Consumer Health News Authors: Lisa Lewis Tags: Uncategorized health heat stroke high school sports Source Type: news
‘His Entire Body Was Shutting Down.’ New State Rankings Show Gaps in High School Athlete Safety
By mid-afternoon on August 1, 2017, the temperature in Stockton, Calif. was at least 105 degrees. Thirteen-year-old Jayden Galbert complained to his mother, Shynelle Jones, about the heat, but didn’t want to skip preseason football practice and hurt his chances of making the freshman football team. Instead, he showed up, pushed himself to participate, and then collapsed on the field. “He started vomiting and he was shaking,” Jones says. “He couldn’t see. He was trying to focus, but he couldn’t.” Jayden was eventually airlifted to UC Davis Medical Center, where he was diagnosed with...
Source: TIME: Health - August 22, 2018 Category: Consumer Health News Authors: Lisa Lewis Tags: Uncategorized health heat stroke high school sports Source Type: news
The Influence of Microneedles on the Percutaneous Penetration of Selected Antihypertensive Agents: Diltiazem Hydrochloride and Perindopril Erbumine.
Abstract
It is well documented in the scientific literature that high blood pressure can lead to cardiovascular disease. Untreated hypertension has clinical consequences such as coronary artery disease, stroke or kidney failure. Diltiazem hydrochloride (DH), a calcium-channel blocker, and perindopril erbumine (PE), an inhibitor of the angiotensin converting enzyme are used for the management of hypertension. This project will examine the effect of microneedle rollers on the transport of DH and PE across pig ear skin. The use of the transcutaneous route of administration reduces and in sometimes eliminates the trau...
Source: Current Drug Delivery - July 30, 2018 Category: Drugs & Pharmacology Authors: Luu E, Ita KB, Morra MJ, Popova IE Tags: Curr Drug Deliv Source Type: research
Validation of an automated bilateral feet cold pressor test
In conclusion, the automated bilateral feet CPT is a valid and feasible stress test modification. Hemodynamic, subjective and endocrine stress responses are substantial, suggesting that this test version represents an advanced and suitable tool in human stress research.
Source: International Journal of Psychophysiology - November 7, 2017 Category: Psychiatry & Psychology Source Type: research
Not as Simple as Canker Sores
BY NANA P. MATSUMOTO, & DEREK MEEKS, DOA 16-year-old boy presented to a rural ED with a swollen jaw, painful blisters in the mouth, and earache for the past day. One week before, he had a fever with chills, sore throat, and dry coughs. He was not taking any medications, and his immunizations were up-to-date. He had a mild learning disorder but no significant past medical or surgical history.An apthous ulcer, the most common and one of the earliest signs of Behçet's disease.The patient's vital signs were within normal limits, and his physical examination revealed anterior cervical lymphadenopathy, sinus con...
Source: The Case Files - October 11, 2017 Category: Emergency Medicine Tags: Blog Posts Source Type: research
Early Palliative Care Consultation Decreases Length of Stay in Severe Stroke Patients (P1.211)
Conclusions:Early PCC in severe stroke patients decreased hospital LOS by 3 days. This may be due to prompt clarification of goals of care and hastened discharge to hospice. Advanced age, poor pre-stroke functional status, and severe post-stroke deficits and disability warrant early PCC. In addition to decreasing LOS, further study is needed to determine whether early PCC also limits futile tests, procedures, and iatrogenic complications. Ultimately, timely identification of PCC candidates may produce higher satisfaction and decreased hospital costs.Disclosure: Dr. Schloss has nothing to disclose. Dr. Tversky has nothing t...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Schloss, E. R., Tversky, S., Katz, J. M., Wright, P. Tags: Pain and Palliative Care Source Type: research
What Causes Hyperammonemia?
Discussion
Reye’s syndrome (RS)is named for Dr. Douglas Reye who along with Drs. G. Morgan and J. Baral described encephalopathy and fatty accumulation and degeneration in children in a 1963 Lancet article. RS usually affects children but can occur at all ages. All organs can be affected but the liver and brain are primarily affected causing liver failure and encephalopathy as toxic metabolites (especially ammonia) accumulate, and intracranial hypertension and cerebral edema occurs. As the ammonia levels begin to rise (> 100 mg/dL) patients lose their appetite, have nausea and emesis and mental status changes whic...
Source: PediatricEducation.org - February 20, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Delirium after cardiac surgery: A pilot study from a single tertiary referral center.
CONCLUSIONS: Patients who developed delirium had systemic disease in the form of hypertension and cerebrovascular disease. Delirium was seen in patients who had higher postoperative pain scores, longer ICU stay, and NIV use. This study can be used to develop a predictive tool for diagnosing postcardiac surgical delirium.
PMID: 28074801 [PubMed - in process]
Source: Annals of Cardiac Anaesthesia - December 31, 2016 Category: Anesthesiology Authors: Kumar AK, Jayant A, Arya VK, Magoon R, Sharma R Tags: Ann Card Anaesth Source Type: research
South Carolina EMS Integrates In-Hospital Sepsis Care into Protocols
Medic 29 is dispatched to a college dorm for a female with chief complaint of lower abdominal and flank pain for the past five days.
The dorm room appears clean and well kept. The patient appears to be a typical 18-year-old college student. She's lying on her bed and is responsive to verbal stimuli, hot to touch, and tachycardic with weak and thready radial pulses at 128. She reports painful urinating for the past 48 hours, general malaise, weakness and nausea.
She appears to have labored respirations with a room air SpO2 reading of 95% and is hypotensive with a systolic blood pressure of 88 mmHg that remains low during tr...
Source: JEMS Patient Care - September 1, 2016 Category: Emergency Medicine Authors: Jason G. Walchok, NRP, FP-C Tags: Patient Care Source Type: news
How Exercise Shapes You, Far Beyond the Gym
(Photo: Grady Reese)
By Bradley Stulberg
When I first started training for marathons a little over ten years ago, my coach told me something I've never forgotten: that I would need to learn how to be comfortable with being uncomfortable. I didn't know it at the time, but that skill, cultivated through running, would help me as much, if not more, off the road as it would on it.
It's not just me, and it's not just running. Ask anyone whose day regularly includes a hard bike ride, sprints in the pool, a complex problem on the climbing wall, or a progressive powerlifting circuit, and they'll likely tell you the same: A diff...
Source: Healthy Living - The Huffington Post - July 1, 2016 Category: Consumer Health News Source Type: news
