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The cardiovascular comorbidity and the risk of stroke by means of CHADS2- VASc scale in patients with chronic obstructive pulmonary disease
Conclusions: the risk of stroke was connected with Index of comorbidity in COPD patients, frequency of cardiovascular comorbidity was high in COPD patients.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Kochetova, E. Tags: Clinical Problems COPD Source Type: research

The outcome of patients with acute stroke requiring intensive care unit admission
Conclusions: The need for mechanical ventilation and hypertension were independent predictors of high mortality in patients admitted to the ICU with acute stroke.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Khassawneh, B., Ibnian, A., Yassin, A., Al-Mistarehi, A., ELeimat, I., Ali, M., Shannaq, A., El-Salem, K. Tags: Acute critical care Source Type: research

Which cardiovascular diseases are most influenced by smoking - a cohort retrospective study
Conclusion: This study suggests that smoking may have a greater impact on the development of stroke (p = 0.012) and HBP (p = 0.025). Smoking also has an impact on the development of AMI, but on a smaller scale (p=0.042). Higher PY values are also influencing the development of CVD (p = 0.035). There was no statistically significant variation between the two groups in the development of DM2.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Carvalho Cordes Amaral Barata, C., Rosa, R., Vieira, A. C., Ferra, J., Fradinho, M., Matos, C., Nogueira, F. Tags: Tobacco, smoking control and health educ. Source Type: research

Right atrial function is associated with right venticular diastolic stiffness: RA-RV interaction in pulmonary arterial hypertension
Conclusions In PAH, RA function is associated with changes in RV function. Despite increased RA stroke work, severe RV diastolic stiffness is associated with reduced RV active filling and increased vena cava backflow. In 50% of patients with high baseline Eed, diastolic stiffness remained high, despite treatment. A reduction in Eed coincided with a large reduction in afterload, increased RV active filling and decreased vena cava backflow.
Source: European Respiratory Journal - June 23, 2022 Category: Respiratory Medicine Authors: Wessels, J. N., Mouratoglou, S. A., van Wezenbeek, J., Handoko, M. L., Marcus, J. T., Meijboom, L. J., Westerhof, B. E., Bogaard, H. J., Strijkers, G. J., Vonk Noordegraaf, A., de Man, F. S. Tags: Pulmonary vascular disease Original Articles: Pulmonary vascular disease Source Type: research

Effects of oxygen supplementation during exercise on hemodynamic responses in patients with pulmonary arterial hypertension
Conclusion: Oxygen supplementation during exercise has favourable hemodynamic effects in PAH patients.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Boutou, A., Dipla, K., Zafeiridis, A., Papadopoulos, S., Chatzikosti, A., Markopoulou, A., Stanopoulos, I., Pitsiou, G. Tags: Clinical respiratory physiology, exercise and functional imaging Source Type: research

Use of a USA population survey to describe tobacco exposure, respiratory symptoms, and chronic diseases among smokers
Conclusion: Our population-based data shows a significant relationship between prolonged tobacco use and frequency of respiratory symptoms as well as some chronic diseases.
Source: European Respiratory Journal - December 23, 2014 Category: Respiratory Medicine Authors: Liu, Y., Pleasants, R., Croft, J., Wheaton, A., Heidari, K., Ohar, J., Kraft, M., Mannino, D., Strange, C. Tags: 6.1 Epidemiology Source Type: research

Left ventricular systolic torsion is correlated to right ventricular dilation in pulmonary hypertension patients
Conclusion: We concluded that left ventricular torsion which plays a key role in left ventricular systolic function and stroke volume is affected in PH patients with MPAP higher than 35 mmHg and is correlated to right ventricular dilation.
Source: European Respiratory Journal - October 30, 2015 Category: Respiratory Medicine Authors: Lamia, B., Molano, L. C., Cuvelier, A., Viacroze, C., Muir, J.-F. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research

The effect of sex and age on the comorbidity burden of OSA: an observational analysis from a large nationwide US health claims database
Obstructive sleep apnoea (OSA) is a highly prevalent condition but studies exploring the burden of OSA-associated comorbidities have been limited by small sample sizes with underrepresentation of women. We queried the Truven Health MarketScan Research Databases 2003–2012, which is a collection of health insurance claims for working adults and retirees with employer-sponsored health insurance. Adults with a diagnostic code for OSA with at least 12 months of follow-up from the index date of OSA diagnosis were compared to a matched random sample. Comorbidities were assessed using International Classification of Dis...
Source: European Respiratory Journal - March 31, 2016 Category: Respiratory Medicine Authors: Mokhlesi, B., Ham, S. A., Gozal, D. Tags: Sleep medicine Original Articles: Sleep Source Type: research

Prevalence of common diseases in COPD patients versus lung-healthy control subjects: Results from the German COSYCONET study
COSYCONET investigates the interrelationship of COPD and comorbidities with regard to course and prognosis of the disease. The present analysis examined the prevalence of selected common diseases in the COPD cohort compared to apparently lung-healthy subjects from the population-based reference cohorts KORA and SHIP.Spirometry was performed in all subjects and COPD patients were graded according to GOLD criteria. Subjects from KORA/SHIP without known COPD, asthma or chronic bronchitis and with FEV1/FVC≥0.7 were regarded as apparently lung-healthy. Prevalences of myocardial infarction, stroke, diabetes, hypertension, obe...
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Karrasch, S., Obst, A., Söhler, S., Thorand, B., Huth, C., Ladwig, K.-H., Flexeder, C., Wacker, M., Peters, A., Heinrich, J., Ewert, R., Nowak, D., Jörres, R. A., Vogelmeier, C., Gläser, S., Schulz, H., COSYCONET Study Group Tags: 6.1 Epidemiology Source Type: research

Prognostic value of hemodynamics following treatment initiation in pulmonary arterial hypertension
Conclusions: Stroke volume index and right atrial pressure at first follow-up catheterization were the best hemodynamic predictors of death or transplantation. These variables should be further validated as treatment targets in a prospective study.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Weatherald, J., Adir, Y., Boucly, A., Savale, L., Simonneau, G., Montani, D., Jaïs, X., Humbert, M., Chemla, D., Sitbon, O., Herve, P. Tags: Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research

Longitudinal cardiac changes in a SUGEN/Hypoxic Rat Model of Pulmonary Hypertension determined by Cardiac MRI
Conclusion: 5 weeks of SuHx resulted in RV dysfunction and RV hypertrophy. Although RV systolic pressure remained elevated throughout the 8 week study period, RV dysfunction and RV hypertrophy had improved demonstrating adaptive remodelling of the SuHx rat RV to the induced persistent PH.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Jayasekera, G., Wilson, K., Buist, H., Hughes, C., Nilsen, M., Church, C., Gallagher, L., Mullin, J., Maclean, M., Holmes, W., Welsh, D., Peacock, A. Tags: Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research

Haemodynamic effects of exercise therapy in stable, optimally treated pulmonary arterial hypertension
Conclusions: Provisional results suggest exercise therapy in PAH has a positive effect on the pressure-flow relationship in the pulmonary circulation, leading to reduced stress on the right ventricle on exertion. This change may improve long term outcomes.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: MacKenzie, A., Ford, J., Jayasekera, G., Crowe, T., Peacock, A., Church, C., Johnson, M. Tags: Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research

Right ventricular contractile reserve and pulmonary arterial compliance differentiate PAH patients with long-term survival and therapeutic success
Conclusions: RV contractile reserve and PA compliance differentiates long-term survivors (>10 years of treatment) from short-term survivors (<2 years of treatment) on PAH specific therapy.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Vanderpool, R., Wickstrom, K., Desai, A., Nair, V., Bernardo, R., Rischard, F. Tags: Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research

Obstructive sleep apnea and specific cardiovascular outcomes
Conclusion: We have demonstrated a high prevalence OSA in respondents. We noted that arterial hypertension and cor hypertonicum were in correlation with the degree of OSA. History of myocardial infarction and stroke reach their peak in study group with AHI 15–30, although this conditions were much higher present in overall respondents with OSA compered to respondents without OSA. We have confirmed by increasing degree of OSA increases the percentage of specific cardiovascular outcomes.
Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Sajnic, A., Trupkovic, A., Zovko, T., Karabatic, S., Lalic, I., Samarzija, M. Tags: Nurses Source Type: research

Late Breaking Abstract - Balloon Pulmonary Angioplasty for the Treatment of Non Operable Chronic Thromboembolic Pulmonary Hypertension - Initial experience of a Belgian Center
Conclusion: In our cohort, we demonstrated that BPA improves most of the haemodynamics variables, including stroke volume index and pulmonary arterial compliance, without severe adverse events. Further studies for the long term efficacy of BPA are required.
Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Godinas, L., Lawrence, B., Werner, B., Catharina, B., Mathias, L., Marion, D., Geert, M. Tags: Pulmonary hypertension Source Type: research

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