Right atrial function is associated with right venticular diastolic stiffness: RA-RV interaction in pulmonary arterial hypertension

Conclusions
In PAH, RA function is associated with changes in RV function. Despite increased RA stroke work, severe RV diastolic stiffness is associated with reduced RV active filling and increased vena cava backflow. In 50% of patients with high baseline Eed, diastolic stiffness remained high, despite treatment. A reduction in Eed coincided with a large reduction in afterload, increased RV active filling and decreased vena cava backflow.

Source: European Respiratory Journal - June 23, 2022 Category: Respiratory Medicine Authors: Wessels, J. N., Mouratoglou, S. A., van Wezenbeek, J., Handoko, M. L., Marcus, J. T., Meijboom, L. J., Westerhof, B. E., Bogaard, H. J., Strijkers, G. J., Vonk Noordegraaf, A., de Man, F. S. Tags: Pulmonary vascular disease Original Articles: Pulmonary vascular disease Source Type: research