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Condition: Hypertension
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Total 52 results found since Jan 2013.

Platelet Count Predicts Adverse Clinical Outcomes After Ischemic Stroke or TIA: Subgroup Analysis of CNSR II
Conclusion: In ischemic stroke or TIA patients with platelet count within normal range, platelet count may be a qualified predictor for long-term recurrent stroke, mortality, and poor functional outcome. Introduction Platelets exert a critical role in the pathogenesis of atherosclerotic complications of cardio-cerebrovascular disease, contributing to thrombus formation, and embolism (1, 2). Previous literature reported that platelets of various size and density are produced by megakaryocytes of different size and stages of maturation in different clinical conditions, suggesting various platelet patterns in differen...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Let's Encourage Congress to Improve Stroke Care FAST
She thought she was choking. It was June of her first year as a member of the Ohio House of Representatives. Joyce Beatty had just returned to her office following a luncheon when she felt her throat shut down. She couldn't swallow, couldn't talk. Couldn't cry for help. As she reached for water, her left side went numb. She collapsed. Someone called 911, thinking it was a heart attack. It was a stroke. Specifically, a brain stem stroke. The brain stem is a precarious spot -- a half-inch wide area that controls basic activities like consciousness, blood pressure and breathing. A stroke there could harm any of those functio...
Source: Healthy Living - The Huffington Post - February 15, 2016 Category: Consumer Health News Source Type: news

Hypertensive Disorders in Pregnancy and Future Risk of Stroke: A Systematic Review (P2.114)
CONCLUSIONS: Hypertension in pregnancy likely carries an increased risk for stroke in later life, especially when associated with pre-eclampsia/eclampsia. There may be benefit in targeting these women for close risk-factor monitoring and control beyond the post-partum period.Disclosure: Dr. Ganesh has nothing to disclose. Dr. Sarna has nothing to disclose. Dr. Mehta has nothing to disclose. Dr. Smith has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ganesh, A., Sarna, N., Mehta, R., Smith, E. Tags: Cerebrovascular Disease and Interventional Neurology: Childhood and Young Adult Source Type: research

Stroke prevention of thoracoscopic left atrial appendage clipping in patients with non-valvular atrial fibrillation at high risk of stroke and bleeding: study protocol for a non-randomised controlled clinical trial
Introduction Non-valvular atrial fibrillation (NVAF) is a high-risk factor for ischaemic stroke. The 2016 European Society of Cardiology Atrial Fibrillation Management guidelines recommend oral anticoagulants (OACs) to prevent stroke in men with CHA2DS2-VASc scores ≥2 and women ≥3. However, in patients with a high risk of stroke and a high risk of bleeding (HAS-BLED (Hypertension, Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile international normalized ratio, Elderly (> 65 years), Drugs/alcohol concomitantly) score≥3), OAC had a higher risk of bleeding. Left atrial appendage cl...
Source: BMJ Open - October 28, 2022 Category: General Medicine Authors: Ye, C., Han, X., Chen, Y., Liu, F., Ma, H., Yang, Y., Liu, Y., Hu, Q., Yao, Q., Xie, W., Xu, D. Tags: Open access, Surgery Source Type: research

Retrospective case review of missed opportunities for primary prevention of stroke and TIA in primary care: protocol paper
This study will investigate: (1) the proportion of strokes/TIAs with prior missed opportunities for prevention in primary care; (2) the influence of patient characteristics on missed prevention opportunities and (3) how the proportion of missed prevention opportunities has changed over time. Methods and analysis A retrospective case review will identify first-ever stroke and patients with TIA between 2000 and 2013 using anonymised electronic medical records extracted from the health improvement network (THIN) database. Four categories of missed opportunities for stroke/TIA prevention will be sought: untreated high blood p...
Source: BMJ Open - November 11, 2014 Category: Journals (General) Authors: Moran, G. M., Calvert, M., Feltham, M. G., Marshall, T. Tags: Open access, Cardiovascular medicine, Epidemiology, General practice / Family practice, Global health Protocol Source Type: research

Relation of Intracranial Stenosis and Elevated Carotid Intimal Medial Thickness in Black Caribbean Ischemic Stroke Patients (P03.187)
CONCLUSIONS: Our preliminary results suggest that increased MCA velocity is independent elevated CIMT, a biomarker for atherosclerosis, in anterior circulation ischemic stroke in CBs. History of hypercholesterolemia appears to be an important risk factor in atherosclerosis in CBs. This data suggests further prospective studies of MCA stenosis mechanisms in CBs are warranted.Disclosure: Dr. Law has nothing to disclose. Dr. Hao has nothing to disclose. Dr. Rojas-Soto has nothing to disclose. Dr. Yu has nothing to disclose. Dr. Baird has received personal compensation for activities as a speaker at the International Conferenc...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Law, S., Hao, Q., Rojas-Soto, D., Yu, H., Baird, A. Tags: P03 Cerebrovascular Disease III Source Type: research

Kidney Case Conference Series: How We Manage Hypertension in a Patient with a Recent Stroke.
PMID: 32393466 [PubMed - as supplied by publisher]
Source: Clinical Journal of the American Society of Nephrology : CJASN - May 10, 2020 Category: Urology & Nephrology Authors: Chang TI, Bhalla V Tags: Clin J Am Soc Nephrol Source Type: research

Study: High blood pressure in mothers during pregnancy raises stroke risk in children
Children with mothers who exhibited high blood pressure during pregnancy show a higher incidence of stroke and heart disease according to a study scheduled for presentation at an online conference this week.
Source: Health News - UPI.com - June 1, 2021 Category: Consumer Health News Source Type: news

Asymptomatic Carotid Stenosis Is Associated With Circadian and Other Variability in Embolus Detection
Conclusions: Embolism associated with asymptomatic carotid stenosis shows circadian variation with highest rates 4–6 h before midday. This corresponds with peak circadian incidence of stroke and other vascular complications. These and ASED Study results show that monitoring frequency, duration, and time of day are important in ES detection. Introduction Transcranial Doppler (TCD) detected microembolism in the ipsilateral middle cerebral artery (MCA) may help stratify the risk of stroke and other arterial disease complications in persons with advanced (≥60%) asymptomatic carotid stenosis. If so, this t...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research

Strokes 'may be linked to temperature', study finds
Conclusion This retrospective study reports that there is an association between lower temperature and increased humidity and a slightly increased risk of ischaemic stroke. It was a large study, but there are several major limitations of this study design: The temperature was matched with discharge dates. There is a wide variation in the length of hospitalisation after a stroke, so the temperature at discharge may be very different to the temperature when the stroke occurred. The researchers assumed that changes in outdoor air temperature would have been experienced by all of the people who suffered from a stroke. It...
Source: NHS News Feed - February 13, 2014 Category: Consumer Health News Tags: Lifestyle/exercise Neurology Source Type: news

Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

FDA Approves Expanded Peripheral Artery Disease (PAD) Indication for XARELTO ® (rivaroxaban) Plus Aspirin to Include Patients After Lower-Extremity Revascularization (LER) Due to Symptomatic PAD
RARITAN, N.J., August 24, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) has approved an expanded peripheral artery disease (PAD) indication for the XARELTO® (rivaroxaban) vascular dose (2.5 mg twice daily plus aspirin 100 mg once daily) to include patients following recent lower-extremity revascularization (LER) due to symptomatic PAD. The approval is based on data from the Phase 3 VOYAGER PAD study. With this approval, XARELTO® is the first and only therapy indicated to help reduce the risks of major cardiovascular (CV) events in p...
Source: Johnson and Johnson - August 24, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Landmark Phase 3 VOYAGER PAD Study of XARELTO ® (rivaroxaban) Plus Aspirin Shows Significant Benefit in Patients with Symptomatic Peripheral Artery Disease (PAD) after Lower-Extremity Revascularization
RARITAN, NJ, March 28, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the VOYAGER PAD study met its primary efficacy and principal safety endpoints, demonstrating the XARELTO® (rivaroxaban) vascular dose (2.5 mg twice daily) plus aspirin (100 mg once daily) was superior to aspirin alone in reducing the risk of major adverse limb and cardiovascular (CV) events by 15 percent in patients with symptomatic peripheral artery disease (PAD) after lower-extremity revascularization, with similar rates of TIMI[1] major bleeding. VOYAGER PAD is the only study to show a significant benefit using...
Source: Johnson and Johnson - March 28, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Janssen Submits Application to U.S. FDA for New Indication to Expand Use of XARELTO ® (rivaroxaban) in Patients with Peripheral Artery Disease
RARITAN, NJ, October 26, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today it has submitted a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for a new indication to expand the use of XARELTO® (rivaroxaban) in patients with peripheral artery disease (PAD). If approved, this new indication for the XARELTO® vascular dose (2.5 mg twice daily plus aspirin 75-100 mg once daily) would include reducing the risk of major thrombotic vascular events such as heart attack, stroke and amputation in patients after recent lower-extremity revascularization, a c...
Source: Johnson and Johnson - October 26, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Aspirin at bedtime 'cuts' morning heart attack risk
Conclusion So far this study has not yet been published in a peer-reviewed journal. Therefore it is not possible to fully assess the quality and methods of this study. Despite the media headlines, and the conclusions of the abstract, the researchers did not measure directly whether aspirin taken at bedtime reduced heart attacks. They measured whether it reduced two risk factors for heart attacks – blood pressure and platelet activity. Taking aspirin at bedtime had no effect on a person’s blood pressure compared with taking it in the morning. They did find that it reduced platelet reactivity, though, by 22 aspirin rea...
Source: NHS News Feed - November 20, 2013 Category: Consumer Health News Tags: Heart/lungs Medical practice Source Type: news