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Condition: Diabetes
Therapy: Thrombolytic Therapy

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Total 115 results found since Jan 2013.

Specificity and sensitivity of the SeLECT score in predicting late seizures in patients undergoing intravenous thrombolytic treatment and the effect of diabetes mellitus and leukoaraiosis
CONCLUSION: We found that DM was an independent risk factor for late seizures after stroke in a patient group receiving thrombolytic therapy, and late seizures after stroke were less frequent in patients with leukoaraiosis.PMID:37059430 | DOI:10.1055/s-0043-1767764
Source: Atherosclerosis - April 14, 2023 Category: Cardiology Authors: Yasemin Din ç Aylin Bican Demir G üven Özkaya Mustafa Bakar Source Type: research

The potential role of insulin resistance in predicting outcome from intravenous thrombolytic therapy
ConclusionInsulin resistance and metabolic syndrome were associated with worse functional outcomes in non-diabetic stroke patients after receiving rt-PA.
Source: Acta Neurologica Belgica - August 20, 2022 Category: Neurology Source Type: research

HAT Score External Validity: A Predictor Of Hemorrhagic Transformation After Intravenous Thrombolysis (P3.107)
CONCLUSIONSThe consistency of the predictive capability of the scale in two great independent cohorts of t-PA-treated patients ( NINDS and HAT score ), and the presence of similar results in our cohort, indicate that this score is likely to have good external validity.Disclosure: Dr. Neto has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Neto, E. Tags: Cerebrovascular Disease and Interventional Neurology: t-PA Source Type: research

Combination Approaches to Attenuate Hemorrhagic Transformation After tPA Thrombolytic Therapy in Patients with Poststroke Hyperglycemia/Diabetes.
Abstract To date, tissue type plasminogen activator (tPA)-based thrombolytic stroke therapy is the only FDA-approved treatment for achieving vascular reperfusion and clinical benefit, but this agent is given to only about 5% of stroke patients in the USA. This may be related, in part, to the elevated risk of symptomatic intracranial hemorrhage, and consequently limited therapeutic time window. Clinical investigations demonstrate that poststroke hyperglycemia is one of the most important risk factors that cause intracerebral hemorrhage and worsen neurological outcomes. There is a knowledge gap in understanding the ...
Source: Advances in Pharmacology - October 15, 2014 Category: Drugs & Pharmacology Authors: Fan X, Jiang Y, Yu Z, Yuan J, Sun X, Xiang S, Lo EH, Wang X Tags: Adv Pharmacol Source Type: research

Le développement actuel de la télémédecine en Allemagne
Conclusion La promulgation récente d’une loi sur l’organisation des soins en Allemagne, incluant la pratique de la télémédecine, et la mise en place d’une stratégie nationale de développement par le ministère fédéral de la Santé sont des signes en faveur d’un développement plus rapide de la télémédecine. Objectives To assess the state of development of telemedicine in Germany in 2013, identify the strengths and weaknesses of existing organisations, as well as the medium-term outlook. Methods Collection of data from the registry established by the institute für Arbeit und Technik and the statistics ...
Source: European Research in Telemedicine - November 1, 2014 Category: Information Technology Source Type: research

Analysis on the correlation factors for hemorrhagic transformation after intravenous thrombolytic therapy.
CONCLUSIONS: Intravenous thrombolysis hemorrhagic transformation associated with these factors including the vessel wall, blood composition and biochemical markers. PMID: 25855925 [PubMed - indexed for MEDLINE]
Source: Pharmacological Reviews - November 20, 2015 Category: Drugs & Pharmacology Authors: Zhang PL, Wang YX, Chen Y, Zhang CH, Li CH, Dong Z, Zhang SS, Tong YF, Li YQ, Tong XG, Wang JH Tags: Eur Rev Med Pharmacol Sci Source Type: research

Relationship Between ST-Segment Recovery and Clinical Outcomes After Primary Percutaneous Coronary Intervention: The HORIZONS-AMI ECG Substudy Report Myocardial Infarction
Conclusions— In this large international study, absent STR 60 minutes after primary PCI was present in 1 in 5 patients with ST-segment–elevation myocardial infarction and was a significant independent predictor of major adverse cardiovascular events and target vessel revascularization at 3 years. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00433966
Source: Circulation: Cardiovascular Interventions - June 18, 2013 Category: Cardiology Authors: Farkouh, M. E., Reiffel, J., Dressler, O., Nikolsky, E., Parise, H., Cristea, E., Baran, D. A., Dizon, J., Merab, J. P., Lansky, A. J., Mehran, R., Stone, G. W. Tags: Electrocardiology, Catheter-based coronary interventions: stents, Acute myocardial infarction Source Type: research

Independent Predictors of Major Adverse Events following Coronary Stenting over 28 Months of Follow-Up
Conclusions: Background diabetes mellitus, prior thrombolytic therapy, PAI-1 and vWF prestenting activity may be useful for MACE prediction over 28 months of follow-up.Cardiology 2015;132:176-181
Source: Cardiology - August 11, 2015 Category: Cardiology Source Type: research

Evaluating safety of thrombolysis in chronic kidney disease patients presenting with pulmonary embolism using propensity score matching
AbstractTo assess the safety of thrombolytic therapy in chronic kidney disease (CKD) patients who present with pulmonary embolism (PE). We used the Nationwide Inpatient Sample Database to identify patients who underwent thrombolysis for PE between 2010 and 2014. The patients were divided into two groups: (1) No CKD and (2) CKD. Patients with and without CKD were matched using 1:1 propensity score matching and a caliper width of 0.01. The primary outcomes were in-hospital mortality and hemorrhagic events. The secondary outcomes were blood transfusions, length of stay and total hospitalization charge. Two separate, multivari...
Source: Journal of Thrombosis and Thrombolysis - September 1, 2017 Category: Hematology Source Type: research

28675 A case of systemic amyloidosis diagnosed by dermatologic consult
A 49-year-old male with PMH of hypertension and diabetes was admitted to the neurology ICU following thrombolytic therapy for left MCA occlusive thrombus. Dermatology was consulted for desquamation of the lower lip, lateral tongue, and bruising of the eyelid and cheeks. Patient originally presented to outside hospital with bilateral lower extremity swelling and shortness of breath. BNP and troponins were elevated, and ACS protocol was initiated. He had stroke-like symptoms while at the outside facility and CT showed MCA occlusive thrombus.
Source: Journal of the American Academy of Dermatology - August 8, 2021 Category: Dermatology Authors: Alison Huber, Dr. Emily Smith Source Type: research