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Specialty: General Medicine
Condition: Heart Failure
Education: Study
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Total 484 results found since Jan 2013.
FATA Study: Prevalence of Atrial Fibrillation and Antithrombotic Therapy in Primary Health Care in a Northern City of Portugal.
CONCLUSION: The prevalence of atrial fibrillation as well as the frequency of the main comorbidities associated with it are in line with the majority of studies. Although most patients are undergoing oral anticoagulation, only 56.8% of those with atrial fibrillation was performing adequate antithrombotic therapy as recommended by the European Society of Cardiology guidelines, which denote a marked underutilization of this treatment.
PMID: 25817496 [PubMed - as supplied by publisher]
Source: Acta Medica Portuguesa - April 2, 2015 Category: Journals (General) Tags: Acta Med Port Source Type: research
Beta-adrenergic blockers for perioperative cardiac risk reduction in people undergoing vascular surgery.
CONCLUSIONS: This meta-analysis currently offers no clear evidence that perioperative beta-adrenergic blockade reduces postoperative cardiac morbidity and mortality in people undergoing major non-cardiac vascular surgery. There is evidence that intra-operative bradycardia and hypotension are more likely in people taking perioperative beta-adrenergic blockers, which should be weighed with any benefit.
PMID: 25879091 [PubMed - in process]
Source: Cochrane Database of Systematic Reviews - April 17, 2015 Category: Journals (General) Authors: Mostafaie K, Bedenis R, Harrington D Tags: Cochrane Database Syst Rev Source Type: research
Red blood cell transfusion for people undergoing hip fracture surgery.
CONCLUSIONS: We found low quality evidence of no difference in mortality, functional recovery or postoperative morbidity between 'liberal' versus 'restrictive' thresholds for red blood cell transfusion in people undergoing surgery for hip fracture. Although further research may change the estimates of effect, the currently available evidence does not support the use of liberal red blood cell transfusion thresholds based on a 10 g/dL haemoglobin trigger in preference to more restrictive transfusion thresholds based on lower haemoglobin levels or symptoms of anaemia in these people. Future research needs to address the effec...
Source: Cochrane Database of Systematic Reviews - April 21, 2015 Category: Journals (General) Authors: Brunskill SJ, Millette SL, Shokoohi A, Pulford EC, Doree C, Murphy MF, Stanworth S Tags: Cochrane Database Syst Rev Source Type: research
Depression, anxiety and major adverse cardiovascular and cerebrovascular events in patients following coronary artery bypass graft surgery: a five year longitudinal cohort study
Conclusions:
Generalized anxiety disorder was significantly associated with MACCE at follow-up after CABG surgery. The findings encourage further research pertaining to generalized anxiety disorder, and theoretical conceptualizations of depression, general distress and anxiety in persons undergoing CABG surgery.
Source: BioMed Central - May 25, 2015 Category: Journals (General) Authors: Phillip TullyHelen WinefieldRobert BakerJohan DenolletSusanne PedersenGary WittertDeborah Turnbull Source Type: research
Summer Syncope Syndrome Redux
The objective of the present study was to investigate whether the results of our prior study involving continued use of antihypertensive drugs at the same dosage in the summer as in the winter months for patients living in the Sonoran desert resulted in an increase in syncopal episodes during the hot summer months.
Source: The American Journal of Medicine - June 4, 2015 Category: Journals (General) Authors: Jennifer Juxiang Huang, Chirag Desai, Nirmal Singh, Natasha Sharda, Irbaz Riaz, Joseph Alpert Tags: Brief Observation Source Type: research
Prevalence and determinants of excessive daytime sleepiness in hypertensive patients: a cross-sectional study in Douala, Cameroon
Conclusions
A significant proportion of hypertensive patients suffer from EDS and present a high risk of sleep apnoea. Preventive measures targeted on weight loss, type 2 diabetes and snoring should be considered among these patients.
Source: BMJ Open - July 29, 2015 Category: Journals (General) Authors: Mbatchou Ngahane, B. H., Nganda, M. M., Dzudie, A., Luma, H., Kamdem, F., Ngote, H. R., Monkam, Y., Kuaban, C. Tags: Open access, Cardiovascular medicine, Respiratory medicine Research Source Type: research
Upstream therapeutic strategies of Valsartan and Fluvastatin on Hypertensive patients with non-permanent Atrial Fibrillation (VF-HT-AF): study protocol for a randomized controlled trial
This study was designed to examine whether valsartan or fluvastatin can reduce the risk of non-permanent AF in patients with hypertension.Methods/designThe VF-HT-AF study is a multicenter, randomized, open-label, four-arm parallel group study with comparative evaluation of valsartan and fluvastatin as upstream therapies for the treatment of non-permanent AF complicated by hypertension. The primary outcome measure is change in the development of paroxysmal AF into persistent or permanent AF, the development of persistent AF to permanent AF, and change in incidence of overall and persistent AF recurrence, as evaluated by 7-d...
Source: Trials - August 7, 2015 Category: Journals (General) Authors: Wen-Wei QiTong LiuGang XuLi-Feng LiYing-Zi LiangLan YeGuang-Ping Li Source Type: research
CHA 2 DS 2 -VASc Accuracy for Predicting Heart Failure Outcomes
This cohort study assessed the accuracy of the CHA2DS2-VASc score for predicting ischemic stroke, thromboembolism, and death in patients with heart failure with and without atrial fibrillation.
Source: JAMA - Journal of the American Medical Association - August 30, 2015 Category: Journals (General) Source Type: research
Value of Low Triiodothyronine and Subclinical Myocardial Injury for Clinical Outcomes in Chest Pain.
CONCLUSIONS: In patients with chest pain without clinically obvious CHD, high hs-cTnT combined with low T3 was associated with adverse cardiac/CCV events and was an independent predictor of overall events even after adjustment. These data suggest the importance of systemic factors, such as low T3 syndrome, in the development of adverse cardiac/CCV events beyond advancing clinical atherosclerotic coronary disease in patients with chest pain.
PMID: 26379043 [PubMed - as supplied by publisher]
Source: The American Journal of the Medical Sciences - September 16, 2015 Category: Journals (General) Authors: Lee YM, Ki YJ, Choi DH, Kim BB, Shin BC, Song H, Kim DM Tags: Am J Med Sci Source Type: research
Prognostic impact of neutrophil gelatinase-associated lipocalin and B-type natriuretic in patients with ST-elevation myocardial infarction treated by primary PCI: a prospective observational cohort study
Conclusions
The measurement of NGAL together with the TIMI score results in a strong prognostic model for the 1-year mortality rate in patients with STEMI.
Source: BMJ Open - October 5, 2015 Category: Journals (General) Authors: Helanova, K., Littnerova, S., Kubena, P., Ganovska, E., Pavlusova, M., Kubkova, L., Jarkovsky, J., Pavkova Goldbergova, M., Lipkova, J., Gottwaldova, J., Kala, P., Toman, O., Dastych, M., Spinar, J., Parenica, J., Dostalova Tags: Open access, Cardiovascular medicine, Intensive care Research Source Type: research
Value of Low Triiodothyronine and Subclinical Myocardial Injury for Clinical Outcomes in Chest Pain
Background: Low triiodothyronine (T3) levels and subclinical myocardial injury may be associated with adverse cardiac and cerebrovascular (CCV) events in individuals without clinically apparent coronary heart disease (CHD). The aim of this study was to determine the associations of a low T3 level and subclinical myocardial injury with the development of adverse CCV events in individuals without clinically apparent CHD.
Methods: T3 and high-sensitivity cardiac troponin T (hs-cTnT) levels were analyzed in 250 patients with chest pain free of CHD and heart failure. The primary end point was the composite of sudden cardiac dea...
Source: The American Journal of the Medical Sciences - October 30, 2015 Category: Journals (General) Tags: Clinical Investigation Source Type: research
Transfusion strategy in hematological intensive care unit: study protocol for a randomized controlled trial
Background:
Packed red blood cell (PRBC) transfusion is required in hematology patients treated with chemotherapy for acute leukemia, autologous (auto) or allogeneic (allo) hematopoietic stem cell transplantation (HSCT). In certain situations like septic shock, hip surgery, coronary disease or gastrointestinal hemorrhage, a restrictive transfusion strategy is associated with a reduction of infection and death. A transfusion strategy using a single PRBC unit has been retrospectively investigated and showed a safe reduction of PRBC consumption and costs. We therefore designed a study to prospectively demonstrate that the tra...
Source: Trials - November 23, 2015 Category: Journals (General) Authors: Sylvain ChantepieJean-Baptiste MearLydia GuittetBenoît DervauxJean-Pierre MarolleauFabrice JardinJean-Jacques DutheilJean-Jacques ParientiJean-Pierre VilqueOumedaly Reman Source Type: research
Clinical implications of non sarcomeric gene polymorphisms in hypertrophic cardiomyopathy
ConclusionOur study suggests that COL1A1 polymorphism (2046G>T) is an independent predictor of prognosis in HCM patients supporting the importance of non‐sarcomeric genes on clinical prognosis in HCM.This article is protected by copyright. All rights reserved.
Source: European Journal of Clinical Investigation - November 29, 2015 Category: Journals (General) Authors: Antonio García‐Honrubia, Diana Hernández‐Romero, Esteban Orenes‐Piñero, Ana Isabel Romero‐Aniorte, Vicente Climent, Miriam García, Noemí Garrigos‐Gómez, Concepción Moro, Mariano Valdés, Francisco Marín Tags: Original Paper Source Type: research
Clinical characteristics, management and 1-year outcomes of patients with acute coronary syndrome in Iran: the Iranian Project for Assessment of Coronary Events 2 (IPACE2)
Conclusions
Our study showed that the composition of Iranian patients with ACS regarding the type of ACS is similar to that in developed European countries and is unlike that in developing countries of the Middle East and Africa. We found that our patients with ACS are treated with high levels of adherence to guideline-recommended in-hospital medications.
Source: BMJ Open - December 15, 2015 Category: Journals (General) Authors: Kassaian, S. E., Masoudkabir, F., Sezavar, H., Mohammadi, M., Pourmoghaddas, A., Kojouri, J., Ghaffari, S., Sanaati, H., Alaeddini, F., Pourmirza, B., Mir, E., on-behalf of the IPACE2 registry investigators Tags: Open access, Cardiovascular medicine, Evidence based practice, Medical management Research Source Type: research
In-home care for optimizing chronic disease management in the community: an evidence-based analysis.
CONCLUSIONS: In summary, education-based in-home care is effective at improving outcomes of patients with a range of heart disease severity when delivered by nurses during a single home visit or on an ongoing basis. In-home visits by occupational therapists and physical therapists targeting modification of tasks and the home environment improved functional activities for community-living adults with chronic disease.
PMID: 24167539 [PubMed - indexed for MEDLINE]
Source: Ontario Health Technology Assessment Series - December 20, 2015 Category: Journals (General) Tags: Ont Health Technol Assess Ser Source Type: research
