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Condition: Heart Failure
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Total 70 results found since Jan 2013.

Safety and efficacy of a self-expanding versus a balloon-expandable bioprosthesis for transcatheter aortic valve replacement in patients with symptomatic severe aortic stenosis: a randomised non-inferiority trial
Publication date: Available online 27 September 2019Source: The LancetAuthor(s): Jonas Lanz, Won-Keun Kim, Thomas Walther, Christof Burgdorf, Helge Möllmann, Axel Linke, Simon Redwood, Christian Thilo, Michael Hilker, Michael Joner, Holger Thiele, Lars Conzelmann, Lenard Conradi, Sebastian Kerber, Gerhard Schymik, Bernard Prendergast, Oliver Husser, Stefan Stortecky, Dik Heg, Peter JüniSummaryBackgroundTranscatheter aortic valve replacement (TAVR) is the preferred treatment option for older patients with symptomatic severe aortic stenosis. Differences in the properties of available TAVR systems can affect clinical outcom...
Source: The Lancet - September 28, 2019 Category: General Medicine Source Type: research

Different Risk Profiles of European Patients Using Direct Oral Anticoagulants or Vitamin K Antagonists: a Rapid Review
AbstractPurpose of ReviewWe investigated the risk profiles of patients using direct oral anticoagulants (DOAC) or vitamin K antagonists (VKA) in European cohort studies to estimate the importance of potential (measured or unmeasured) confounding factors in analyses comparing these drugs. We searched MEDLINE and EMBASE (2008 –2018) for relevant studies and extracted information on age, sex, comorbidity, Charlson comorbidity index, HAS-BLED score (assessing risk of bleeding) and CHA2DS2-VASc score (assessing risk of stroke).Recent FindingsOverall, 66 studies with 2,808,757 patients were included. Most patients were from Fr...
Source: Current Epidemiology Reports - November 14, 2020 Category: Epidemiology Source Type: research

Refined atrial fibrillation screening and cost-effectiveness in the German population
Conclusions In our middle-aged population cohort, we identified 0.2% new AF by single timepoint screening. There was a significant estimated risk of stroke and heart failure in these individuals. Cost-effectiveness for screening may be reached in individuals aged 65 years and older. The simple age cut-off is not improved by using Nt-proBNP as a biomarker to guide a screening programme.
Source: Heart - February 24, 2022 Category: Cardiology Authors: Schnabel, R. B., Wallenhorst, C., Engler, D., Blankenberg, S., Pfeiffer, N., Spruenker, N. A., Buettner, M., Michal, M., Lackner, K. J., Münzel, T., Wild, P. S., Martinez, C., Freedman, B., Gutenberg Health Study investigators Tags: Open access Cardiac risk factors and prevention Source Type: research

Empagliflozin cardiovascular and renal effectiveness and safety compared to dipeptidyl peptidase-4 inhibitors across 11 countries in Europe and Asia: Results from the EMPagliflozin compaRative effectIveness and SafEty (EMPRISE) study
Diabetes Metab. 2023 Jan 3:101418. doi: 10.1016/j.diabet.2022.101418. Online ahead of print.ABSTRACTBACKGROUND: Continued expansion of indications for sodium-glucose cotransporter-2 inhibitors increases importance of evaluating cardiovascular and kidney efficacy and safety of empagliflozin in patients with type 2 diabetes compared to similar therapies.METHODS: The EMPRISE Europe and Asia study is a non-interventional cohort study using data from 2014-2019 in seven European (Denmark, Finland, Germany, Norway, Spain, Sweden, United Kingdom) and four Asian (Israel, Japan, South Korea, Taiwan) countries. Patients with type 2 d...
Source: Diabetes and Metabolism - January 7, 2023 Category: Endocrinology Authors: Avraham Karasik Stefanie Lanzinger Elise Chia-Hui Tan Daisuke Yabe Dae Jung Kim Wayne H-H Sheu Cheli Melzer-Cohen Reinhard W Holl Kyoung Hwa Ha Kamlesh Khunti Francesco Zaccardi Anuradhaa Subramanian Krishnarajah Nirantharakumar Thomas Nystr öm Leo Niska Source Type: research

Comparison of telemonitoring combined with intensive patient support with standard care in patients with chronic cardiovascular disease - a randomized clinical trial
Conclusions and relevanceAmong patients with atrial fibrillation, heart failure, or treatment-resistant hypertension, the NICC approach was not superior over SoC, despite a significant reduction in all-cause mortality, stroke, myocardial infarction and cardiac decompensation.Trial registration ClinicalTrials.gov Identifier: NCT03317951.
Source: European Journal of Medical Research - January 11, 2023 Category: Research Source Type: research

Bacteria and your broken heart
In your screening for heart disease, I bet your doctor will never think to check your gut. And that may well be where your heart problems start. Let me explain… Your gut plays a critical role in your overall health. It’s a major part of your body’s ecosystem. It’s home to trillions of bacteria, viruses and fungi. They make up your “microbiome.” Doctors are beginning to pay attention when it comes to these bacteria. But they’re still missing the big picture. This microcosm affects just about every organ and body system. Some of these gut bugs cause disease and infection. Others boost your immune system. Stil...
Source: Al Sears, MD Natural Remedies - October 19, 2017 Category: Complementary Medicine Authors: Cathy Card Tags: Heart Health Source Type: news

Can we go beyond surrogates?
Two years ago, data presented at the annual American Diabetes Association (ADA) meeting in New Orleans showed a marked decrease in deaths, especially those due to cardiovascular disease, with the use of empagliflozin. Two major questions have been asked: (i) was the result a fluke; and (ii) was it a class effect, or was it specific to the agent used? The hope that both questions would be answered by a second study has been answered: the conclusions of EMPA‐REG were not an anomaly and it is a class effect, not one caused by a specific drug. Importantly, do these studies require us to alter our algorithms for the treatment...
Source: Journal of Diabetes - October 19, 2017 Category: Endocrinology Authors: Andrew Drexler Tags: Editorial Source Type: research

Association of inflammatory biomarkers with comorbidity in chronic obstructive pulmonary disease - results from the COSYCONET cohort
Conclusion: WBC correlates with disease severity and is associated with relevant comorbidities. Other classical inflammatory biomarkers did not show a clear correlation with COPD severity of existing comorbidity.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Seiler, F., Trudzinski, F. C., Alquadrah, M., Fähndrich, S., Watz, H., Jörres, R. A., Koch, A., Welte, T., Vogelmeier, C. F., Biertz, F., Bals, R. Tags: Monitoring Airway Disease Source Type: research

How Loud Noise Exposure Is Linked to Heart Disease
If you live near an airport, railroad tracks or a busy road, you might be concerned about how fumes from those planes, trains and automobiles are affecting your health. But according to a new review in the Journal of the American College of Cardiology, there may be another threat to worry about: high levels of noise that may be bad for your heart. A connection between noise pollution and cardiovascular disease has been observed in numerous studies over the years, the authors of the new review said. High decibel levels from road traffic and airplanes, for example, has been linked to high blood pressure, coronary artery dise...
Source: TIME: Health - February 6, 2018 Category: Consumer Health News Authors: Amanda MacMillan Tags: Uncategorized are loud noises unhealthy healthytime Heart Disease heart disease risks heart health Journal of the American College of Cardiology noise level meter noise meter noise pollution noise-cancelling headphones onetime Rese Source Type: news

Assessing incident cardiovascular and metabolic diseases in epidemiological cohort studies in Germany.
CONCLUSIONS: Our results highlight the central role of self-reporting and the efforts associated with identification and verification of disease endpoints in cohort studies. They also provide a basis for future population-based studies that aim for standardized assessment of the incidence of cardiovascular and metabolic diseases. PMID: 29487975 [PubMed - as supplied by publisher]
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - February 27, 2018 Category: International Medicine & Public Health Authors: Herrmann WJ, Weikert C, Bergmann M, Boeing H, Katzke VA, Kaaks R, Tiller D, Greiser KH, Heier M, Meisinger C, Schmidt CO, Neuhauser H, Heidemann C, Jünger C, Wild PS, Schramm SH, Jöckel KH, Dörr M, Pischon T Tags: Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz Source Type: research

EBR Systems launches trial for wireless pacer
EBR Systems said yesterday that it launched a 350-patient investigational device exemption trial of its Wise wireless pacemaker it hopes to use to win FDA approval. Sunnyvale, Calif.-based EBR’s device uses a subcutaneous generator to wirelessly deliver ultrasound energy to a “pellet” implanted in the right ventricle, which it uses to synchronize the left and right ventricles. The system is designed to eliminate the need for a left ventricular lead by allowing the operating physician to place the stimulation “pellet” in a patient-specific location inside the left ventricle. The FDA approved the Solve-CRT stu...
Source: Mass Device - March 8, 2018 Category: Medical Devices Authors: Brad Perriello Tags: Cardiovascular Clinical Trials Cardiac Rhythm Management EBR Systems Inc. Source Type: news

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