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Condition: Heart Failure
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Total 181 results found since Jan 2013.

Importance of Considering Competing Risks in Time-to-Event Analyses: Application to Stroke Risk in a Retrospective Cohort Study of Elderly Patients With Atrial Fibrillation Original Articles
Conclusions: The incidence of death without stroke was 9-fold higher than that of stroke, leading to biased estimates of stroke risk with traditional time-to-event methods. Statistical methods that appropriately account for competing risks should be used to mitigate this bias.
Source: Circulation: Cardiovascular Quality and Outcomes - July 11, 2018 Category: Cardiology Authors: Abdel-Qadir, H., Fang, J., Lee, D. S., Tu, J. V., Amir, E., Austin, P. C., Anderson, G. M. Tags: Atrial Fibrillation, Epidemiology, Primary Prevention, Cerebrovascular Disease/Stroke Original Articles Source Type: research

XANTUS-EL: A real-world, prospective, observational study of patients treated with rivaroxaban for stroke prevention in atrial fibrillation in Eastern Europe, Middle East, Africa and Latin America
ConclusionsXANTUS-EL confirmed low stroke and major bleeding rates in patients with NVAF from EEMEA and Latin America. The population was younger but with more heart failure and hypertension than XANTUS; stroke/SE rate was similar but major bleeding lower.
Source: The Egyptian Heart Journal - October 5, 2018 Category: Cardiology Source Type: research

Discharge Destination from a Rehabilitation Unit After Acute Ischemic Stroke.
CONCLUSIONS: Several easily measured variables were significantly associated with discharge to LTC versus home following stroke rehabilitation. PMID: 30739610 [PubMed - as supplied by publisher]
Source: The Canadian Journal of Neurological Sciences - February 11, 2019 Category: Neurology Authors: Saab A, Glass-Kaastra S, Young GB Tags: Can J Neurol Sci Source Type: research

Flow, Reflected by Stroke Volume Index, is a Risk Marker in High Gradient Aortic Stenosis Patients Undergoing Transcatheter Aortic Valve Replacement
ConclusionsSVi can further characterise patients with HG-AS and may help to identify those who are at increased risk following TAVR.
Source: Canadian Journal of Cardiology - August 30, 2019 Category: Cardiology Source Type: research

Flow, Reflected by Stroke Volume Index, Is a Risk Marker in High-Gradient Aortic Stenosis Patients Undergoing Transcatheter Aortic Valve Replacement
ConclusionsSVi can further characterize patients with HG-AS and may help to identify those who are at increased risk after TAVR.RésuméContexteDes outils sont nécessaires pour dépister les patients exposés à un risque accru à la suite d’un remplacement valvulaire aortique par cathéter (RVAC). Le volume systolique indexé (VSI) est une mesure échocardiographique utilisée dans les cas de sténose aortique à faible gradient. Nous avons vérifié si un faible VSI était un marqueur de risque accru chez les patients présentant une sténose aortique à gradient élevé et avons évalué comment la relation entre le ...
Source: Canadian Journal of Cardiology - December 24, 2019 Category: Cardiology Source Type: research

Any type of physical exercise is good for the heart
Conclusion This study shows that all physical activity, in any form, is good for us. This includes both recreational and non-recreational activities. Don't be misled by some of the media: non-recreational activities like housework are not "better" than recreational activities like playing sports or going to the gym. The fact that reduced risk was seen with non-recreational activity across all countries, but only seen with recreational activity in high-income countries was probably just because fewer people in lower-income countries play sports or go to the gym. The researchers estimate that 8% of all deaths and...
Source: NHS News Feed - September 22, 2017 Category: Consumer Health News Tags: Lifestyle/exercise Source Type: news

Comparison of Readmission and Death Among Patients With Cardiac Disease in Northern vs Southern Ontario
ConclusionsReadmissions were increased in those residing and hospitalized in the North. To reduce readmissions in the North, the quality of postacute transitional care should be examined further.RésuméContexteDes facteurs géographiques peuvent influer sur l’issue de maladies cardiovasculaires au Canada. Les maladies du système circulatoire constituent une raison majeure du taux de mortalité élevé dans le nord de l’Ontario, mais on ne sait pas si les patients hospitalisés pour une maladie cardiovasculaire connaissent des issues différentes par rapport aux personnes vivant dans le sud.MéthodologieNous avons exa...
Source: Canadian Journal of Cardiology - March 1, 2019 Category: Cardiology Source Type: research

Mechanisms, Clinical Significance, and Prevention of Cognitive Impairment in Patients With Atrial Fibrillation
Publication date: December 2017 Source:Canadian Journal of Cardiology, Volume 33, Issue 12 Author(s): Lena Rivard, Paul Khairy Atrial fibrillation (AF) and dementia are major health issues, with growing evidence suggesting a consistent association between AF and all forms of dementia. Although dementia and AF share several risk factors, the association appears to be independent of a history of clinical stroke and other comorbidities such as hypertension, heart failure, and diabetes. Proposed mechanisms linking AF to cognitive decline include altered hemodynamics resulting in cerebral hypoperfusion, inflammation, genetic f...
Source: Canadian Journal of Cardiology - December 3, 2017 Category: Cardiology Source Type: research

Patterns of incidence rates of cardiac complications in patients with congenital heart disease
ConclusionsCardiac complications are frequent in congenital heart disease. Apart from perioperative stroke and complete heart block, incidence rates are low in childhood but the incidence increases during adult life. These data underscore the need of life-long follow up and may help for better allocation of resources maintaining follow-up.
Source: Canadian Journal of Cardiology - October 4, 2018 Category: Cardiology Source Type: research

Update in Cardiovascular Safety of Incretin-Based Therapy in Adults with Type 2 Diabetes Mellitus: A Meta-Analysis of Cardiovascular Outcome Trials
ConclusionThis meta-analysis demonstrated that GLP-1RAs were associated with a significant reduction in MACE, CV death, stroke, and death from any cause, while DPP-4 inhibitors were comparable to placebo for all CV outcomes, including hospitalizations for HF.
Source: Canadian Journal of Diabetes - April 14, 2019 Category: Endocrinology Source Type: research

Prothrombotic State in Atrial Fibrillation Patients With One Additional Risk Factor of the CHA2DS2-VASc Score (Beyond Sex)
ConclusionsA prothrombotic state (increased thrombin generation, denser fibrin clots, impaired fibrinolysis, and endothelial injury) characterizes patients with AF with 1 additional clinical stroke risk factor (beyond sex), with age 65-74 years being particularly associated with prothrombotic indices.RésuméContexteLa question de savoir si un état prothrombotique survient chez les patients atteints de fibrillation auriculaire (FA) à faible risque d’accident vasculaire cérébral (AVC) n’a pas été élucidée.MéthodologieNous avons étudié 118 patients atteints de FA présentant un score CHA2DS2-VASc (insuffisance...
Source: Canadian Journal of Cardiology - April 27, 2019 Category: Cardiology Source Type: research

Update on Cardiovascular Safety of Incretin-Based Therapy in Adults With Type 2 Diabetes Mellitus: A Meta-Analysis of Cardiovascular Outcome Trials
ConclusionsThis meta-analysis demonstrated that GLP-1RAs were associated with a significant reduction in major adverse CV events, CV death, stroke and death from any cause, while DPP-4 inhibitors were comparable to placebo for all CV outcomes, including hospitalizations for heart failure.RésuméObjectifsLes auteurs de deux grands essais randomisés ont récemment publié leurs conclusions concernant les effets d'un agoniste du récepteur au glucagon-like peptide-1 (A-GLP-1R) (essai HARMONY) et d'un inhibiteur de la dipeptidyl peptidase 4 (DPP-4) (essai CARMELINA) sur les bénéfices cardiovasculaires (CV) chez les patie...
Source: Canadian Journal of Diabetes - June 5, 2019 Category: Endocrinology Source Type: research

Role of Non ‐Steroidal Anti‐Inflammatory Drugs (NSAIDs) in the Association between Osteoarthritis and Cardiovascular Diseases: A Longitudinal Study
ConclusionFindings of this first study to evaluate NSAID's mediating role in OA ‐CVD relationship suggest that NSAID use substantially contributes to the OA‐CVD association.This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatology - August 5, 2019 Category: Rheumatology Authors: Mohammad Atiquzzaman, Mohammad E. Karim, Jacek Kopec, Hubert Wong, Aslam H. Anis Tags: Full Length Source Type: research

Role of Nonsteroidal Antiinflammatory Drugs in the Association Between Osteoarthritis and Cardiovascular Diseases: A Longitudinal Study
ConclusionThe findings of this first study to evaluate the mediating role of NSAIDs in the relationship between OA and CVD suggest that NSAID use contributes substantially to the OA –CVD association.
Source: Arthritis and Rheumatology - September 4, 2019 Category: Rheumatology Authors: Mohammad Atiquzzaman, Mohammad E. Karim, Jacek Kopec, Hubert Wong, Aslam H. Anis Tags: Original Article Source Type: research

Biosense Webster Unveils Late-Breaking Results from PRECEPT Study in Patients with Persistent Atrial Fibrillation
IRVINE, CA – May 8, 2020 – Johnson & Johnson Medical Devices Companies* today announced that Biosense Webster, Inc.’s THERMOCOOL SMARTTOUCH® SF Ablation Catheter, evaluated in the PRECEPT study for the treatment of persistent atrial fibrillation (AF), resulted in freedom from any documented, symptomatic atrial arrhythmias at 15 months post-procedure for eight out of ten study participants (80.4 percent).1 Use of the THERMOCOOL SMARTTOUCH SF CATHETER for persistent atrial fibrillation is investigational only. This PRECEPT study data support a Premarket Approval supplement application to the U.S. Food and Drug Adm...
Source: Johnson and Johnson - May 12, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news