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Condition: Diabetes Type 2

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Total 3594 results found since Jan 2013.

Pioglitazone for Secondary Stroke Prevention Clinical Sciences
Conclusions—Pioglitazone reduces recurrent stroke and major vascular events in ischemic stroke patients with insulin resistance, prediabetes, and diabetes mellitus.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Meng Lee, Jeffrey L. Saver, Hung-Wei Liao, Chun-Hsien Lin, Bruce Ovbiagele Tags: Cardiovascular Disease, Diabetes, Type 2, Secondary Prevention, Meta Analysis, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Stress Hyperglycemia and Prognosis of Minor Ischemic Stroke and Transient Ischemic Attack Clinical Sciences
Conclusions—Stress hyperglycemia, measured by glucose/GA ratio, was associated with an increased risk of stroke in patients with a minor ischemic stroke or transient ischemic attack.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00979589.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Yuesong Pan, Xueli Cai, Jing Jing, Xia Meng, Hao Li, Yongjun Wang, Xingquan Zhao, Liping Liu, David Wang, S. Claiborne Johnston, Tiemin Wei, Yilong Wang Tags: Diabetes, Type 2, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Body Mass Index and Stroke Risk Among Patients With Type 2 Diabetes Mellitus Clinical Sciences
Conclusions— The present study demonstrates an inverse association between BMI and stroke risk among patients with type 2 diabetes mellitus.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Li, W., Katzmarzyk, P. T., Horswell, R., Zhang, Y., Zhao, W., Wang, Y., Johnson, J., Hu, G. Tags: Obesity, Type 2 diabetes, Risk Factors for Stroke, Epidemiology Clinical Sciences Source Type: research

Prognosis of Ischemic Stroke With Newly Diagnosed Diabetes Mellitus According to Hemoglobin A1c Criteria in Chinese Population Clinical Sciences
Conclusions— NDDM by new criteria was associated with poor prognosis at 1 year after ischemic stroke; however, NDDM with single high HbA1c did not predict a poor prognosis.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Jing, J., Pan, Y., Zhao, X., Zheng, H., Jia, Q., Li, H., Guan, L., Liu, L., Wang, C., Meng, X., He, Y., Wang, Y., Wang, Y. Tags: Diabetes, Type 2, Quality and Outcomes, Ischemic Stroke Clinical Sciences Source Type: research

Vascularization Pattern After Ischemic Stroke is Different in Control Versus Diabetic Rats: Relevance to Stroke Recovery Basic Sciences
Conclusions— Diabetes mellitus impairs poststroke reparative neovascularization and impedes the recovery. Glycemic control after stroke can improve neurovascular repair and improve functional outcome.
Source: Stroke - September 23, 2013 Category: Neurology Authors: Prakash, R., Li, W., Qu, Z., Johnson, M. A., Fagan, S. C., Ergul, A. Tags: Type 2 diabetes, Behavioral Changes and Stroke, Other imaging, Other Vascular biology Basic Sciences Source Type: research

Synergistic Effects of Transplanted Endothelial Progenitor Cells and RWJ 67657 in Diabetic Ischemic Stroke Models Basic Sciences
Conclusions— The combination of EPC transplantation and RWJ administration accelerated recovery from diabetic stroke, which might have been caused by increased levels of proangiogenic and neurotrophic factors.
Source: Stroke - June 22, 2015 Category: Neurology Authors: Bai, Y.-Y., Wang, L., Chang, D., Zhao, Z., Lu, C.-Q., Wang, G., Ju, S. Tags: Type 2 diabetes, Other Stroke Treatment - Medical Basic Sciences Source Type: research

Neurorestorative Therapy of Stroke in Type 2 Diabetes Mellitus Rats Treated With Human Umbilical Cord Blood Cells Basic Sciences
Conclusions— HUCBC treatment initiated 3 days after stroke significantly increased white matter and vascular remodeling in the ischemic brain as well as decreased neuroinflammatory factor expression in the ischemic brain in T2DM rats and promoted M2 macrophage polarization. HUCBC reduction of neuroinflammation and increased vascular and white matter axonal remodeling may contribute to the HUCBC-induced beneficial effects in T2DM stroke rats.
Source: Stroke - August 24, 2015 Category: Neurology Authors: Yan, T., Venkat, P., Chopp, M., Zacharek, A., Ning, R., Cui, Y., Roberts, C., Kuzmin-Nichols, N., Sanberg, C. D., Chen, J. Tags: Type 2 diabetes, Other Treatment, Other Stroke Treatment - Medical Basic Sciences Source Type: research

Pancreatic {beta}-Cell Function and Prognosis of Nondiabetic Patients With Ischemic Stroke Clinical Sciences
Conclusions—In this large-scale registry, β-cell dysfunction was associated with an increased risk of 12-month poor prognosis in nondiabetic patients with ischemic stroke.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Yuesong Pan, Weiqi Chen, Jing Jing, Huaguang Zheng, Qian Jia, Hao Li, Xingquan Zhao, Liping Liu, Yongjun Wang, Yan He, Yilong Wang Tags: Diabetes, Type 2, Secondary Prevention, Ischemic Stroke Original Contributions Source Type: research

Heart Rate Variability and Incident Stroke: The Atherosclerosis Risk in Communities Study Clinical Sciences
Conclusions— Lower HRV was associated with higher risk of incident stroke among middle-aged adults with prevalent diabetes mellitus but not among people without diabetes mellitus.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Fyfe-Johnson, A. L., Muller, C. J., Alonso, A., Folsom, A. R., Gottesman, R. F., Rosamond, W. D., Whitsel, E. A., Agarwal, S. K., MacLehose, R. F. Tags: Autonomic Nervous System, Cardiovascular Disease, Diabetes, Type 2, Risk Factors, Ischemic Stroke Clinical Sciences Source Type: research

Neurorestorative Responses to Delayed Human Mesenchymal Stromal Cells Treatment of Stroke in Type 2 Diabetic Rats Basic Sciences
Conclusions—In T2DM stroke rats, delayed hMSC treatment significantly improves neurological functional outcome and increases neurorestorative effects and M2 macrophage polarization. Increasing brain platelet-derived growth factor expression may contribute to hMSC-induced neurorestoration.
Source: Stroke - October 23, 2016 Category: Neurology Authors: Yan, T., Venkat, P., Chopp, M., Zacharek, A., Ning, R., Roberts, C., Zhang, Y., Lu, M., Chen, J. Tags: Cell Therapy, Stem Cells, Diabetes, Type 2, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Corneal Confocal Microscopy Detects Corneal Nerve Damage in Patients Admitted With Acute Ischemic Stroke Clinical Sciences
Background and Purpose—Corneal confocal microscopy can identify corneal nerve damage in patients with peripheral and central neurodegeneration. However, the use of corneal confocal microscopy in patients presenting with acute ischemic stroke is unknown.Methods—One hundred thirty patients (57 without diabetes mellitus [normal glucose tolerance], 32 with impaired glucose tolerance, and 41 with type 2 diabetes mellitus) admitted with acute ischemic stroke, and 28 age-matched healthy control participants underwent corneal confocal microscopy to quantify corneal nerve fiber density, corneal nerve branch density, and corneal...
Source: Stroke - October 23, 2017 Category: Neurology Authors: Adnan Khan, Naveed Akhtar, Saadat Kamran, Georgios Ponirakis, Ioannis N. Petropoulos, Nahel A. Tunio, Soha R. Dargham, Yahia Imam, Faheem Sartaj, Aijaz Parray, Paula Bourke, Rabia Khan, Mark Santos, Sujatha Joseph, Ashfaq Shuaib, Rayaz A. Malik Tags: Translational Studies, Imaging, Ischemic Stroke Original Contributions Source Type: research

CD133+Exosome Treatment Improves Cardiac Function after Stroke in Type 2 Diabetic Mice
In this study, we tested whether treatment with exosomes harvested from human umbilical cord blood derived CD133+ cells (CD133+Exo) improves cardiac function in type 2 diabetes mellitus (T2DM) stroke mice. Adult (3 –4 m), male, BKS.Cg-m+/+Leprdb/J (db/db, T2DM) and non-DM (db+) mice were randomized to sham or photothrombotic stroke groups. T2DM-stroke mice were treated with phosphate-buffered saline (PBS) or CD133+Exo (20  μg, i.v.) at 3 days after stroke. T2DM sham and T2DM+CD133+Exo treatment groups were included as controls. Echocardiography was performed, and mice were sacrificed at 28 days after stroke. Cardiom...
Source: Translational Stroke Research - March 19, 2020 Category: Neurology Source Type: research

Self-Reported Stroke Risk Stratification Clinical Sciences
Conclusions—A simple self-reported questionnaire can be used to identify those at high risk for stroke better than the gold standard FSRF. This instrument can be used clinically to easily identify individuals at high risk for stroke and also scientifically to identify a subpopulation enriched for stroke risk.
Source: Stroke - June 26, 2017 Category: Neurology Authors: George Howard, Leslie A. McClure, Claudia S. Moy, Virginia J. Howard, Suzanne E. Judd, Ya Yuan, D. Leann Long, Paul Muntner, Monika M. Safford, Dawn O. Kleindorfer Tags: Cardiovascular Disease, Diabetes, Type 2, Epidemiology, Risk Factors, Hypertension Original Contributions Source Type: research

Diet Beverages Linked To Increased Stroke Risk & Heart Attacks
This study, as well as other research on the connection between diet beverages and vascular disease, is observational and cannot show cause and effect. That’s a major limitation, researchers say, as it’s impossible to determine whether the association is due to a specific artificial sweetener, a type of beverage or another hidden health issue. “Postmenopausal women tend to have higher risk for vascular disease because they are lacking the protective effects of natural hormones,” North Carolina cardiologist Dr. Kevin Campbell said, which could contribute to increased risk for heart disease and stroke...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - February 14, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Heart Attack Stroke Source Type: news

Diet Drinks Linked To Increased Stroke Risk & Heart Attacks
This study, as well as other research on the connection between diet beverages and vascular disease, is observational and cannot show cause and effect. That’s a major limitation, researchers say, as it’s impossible to determine whether the association is due to a specific artificial sweetener, a type of beverage or another hidden health issue. “Postmenopausal women tend to have higher risk for vascular disease because they are lacking the protective effects of natural hormones,” North Carolina cardiologist Dr. Kevin Campbell said, which could contribute to increased risk for heart disease and stroke...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - February 14, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Heart Attack Stroke Source Type: news