Neurorestorative Therapy of Stroke in Type 2 Diabetes Mellitus Rats Treated With Human Umbilical Cord Blood Cells [Basic Sciences]

Conclusions—
HUCBC treatment initiated 3 days after stroke significantly increased white matter and vascular remodeling in the ischemic brain as well as decreased neuroinflammatory factor expression in the ischemic brain in T2DM rats and promoted M2 macrophage polarization. HUCBC reduction of neuroinflammation and increased vascular and white matter axonal remodeling may contribute to the HUCBC-induced beneficial effects in T2DM stroke rats.

Source: Stroke - August 24, 2015 Category: Neurology Authors: Yan, T., Venkat, P., Chopp, M., Zacharek, A., Ning, R., Cui, Y., Roberts, C., Kuzmin-Nichols, N., Sanberg, C. D., Chen, J. Tags: Type 2 diabetes, Other Treatment, Other Stroke Treatment - Medical Basic Sciences Source Type: research