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Condition: Cataracts

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Total 121 results found since Jan 2013.

Aging and regeneration in vertebrates.
Abstract Aging is marked by changes that affect organs and resident stem cell function. Shorting of telomeres, DNA damage, oxidative stress, deregulation of genes and proteins, impaired cell-cell communication, and an altered systemic environment cause the eventual demise of cells. At the same time, reparative activities also decline. It is intriguing to correlate aging with the decline of regenerative abilities. Animal models with strong regenerative capabilities imply that aging processes might not be affecting regeneration. In this review, we selectively present age-dependent changes in stem/progenitor cells th...
Source: Current Topics in Developmental Biology - February 15, 2014 Category: Biology Authors: Sousounis K, Baddour JA, Tsonis PA Tags: Curr Top Dev Biol Source Type: research

G.P.157: Clinical and pathological features associated with mutations in MICU1
We present the clinical/pathological features in a cohort of 18 patients. Patients presented between birth and 8years with a mild, relatively static, proximal myopathy associated with high Creatinine Kinase (2000–10,000iu/L), learning difficulties and frequent microcephaly. At follow up (5–28yrs), all remained ambulant but variable extrapyramidal symptoms had developed in the majority by the end of the 1st decade. Other features suggestive of mitochondrial dysfunction included peripheral neuropathy, icthyosis, stroke like episodes, episodic weakness, ataxia and cataracts. Cardiomyopathy was not seen. Serum and CSF lact...
Source: Neuromuscular Disorders - September 4, 2014 Category: Neurology Authors: A.M. Childs, K. Pysden, H. Roper, G. Chow, E.H. Niks, M. Kriek, P.F. Chinnery, D. Lewis-Smith, M. Duchen, G. Szabadkai, C. Logan, E. Sheridan, C. Sewry, F. Muntoni Source Type: research

Smoking and Atherosclerosis: Mechanisms of Disease and New Therapeutic Approaches.
Abstract It has been clear that at least 1 billion adults worldwide are smokers and at least 700 million children are passive smokers at home. Smoking exerts a detrimental effect to many organ systems and is responsible for illnesses such as lung cancer, pneumonia, chronic obstructive pulmonary disease, cancer of head and neck, cancer of the urinary and gastrointestinal tract, periodontal disease, cataract and arthritis. Additionally, smoking is an important modifiable risk factor for the development of cardiovascular disease such as coronary artery disease, stable angina, acute coronary syndromes, sudden death, s...
Source: Current Medicinal Chemistry - August 26, 2014 Category: Chemistry Authors: Siasos G, Tousoulis D, Michalea S, Oikonomou E, Vavuranakis M, Athanasiou D, Tourikis P, Gouliopoulos N, Miliou A, Mazaris S, Papavassiliou AG, Stefanadis C Tags: Curr Med Chem Source Type: research

Prevalence and risk factors of dry eye disease in a British female cohort.
CONCLUSIONS: DED is common and increases with age within this cohort of female twins. We confirmed established risk factors for the first time in a British population, and found important risk factors that might relate to an underlying aetiology involving chronic pain predisposition or somatisation. PMID: 25185440 [PubMed - as supplied by publisher]
Source: The British Journal of Ophthalmology - September 3, 2014 Category: Opthalmology Authors: Vehof J, Kozareva D, Hysi PG, Hammond CJ Tags: Br J Ophthalmol Source Type: research

Self-reported cataracts in older adults in Ghana: sociodemographic and health related factors
Conclusions: Cataract is prevalent in older people in Ghana with approximately 1 in 20 people aged 50 years or older reporting a previous diagnosis of cataract. As cataract surgery is restorative, a public health approach on behavioural modification, well structured national outreach eye care services (for rural residents), inclusion of basic eye health services at sub-district levels, increased family support and national health insurance for older persons is indicated.
Source: Epidemiologic Perspectives and Innovations - September 12, 2014 Category: Epidemiology Authors: Alfred E YawsonEdith M Ackuaku-DogbeNana A SeneadzaGeorge MensahNadia MinicuciNirmala NaidooSomnath ChatterjiPaul KowalRichard B Biritwum Source Type: research

Prevalence and risk factors of dry eye disease in a British female cohort
Conclusions DED is common and increases with age within this cohort of female twins. We confirmed established risk factors for the first time in a British population, and found important risk factors that might relate to an underlying aetiology involving chronic pain predisposition or somatisation.
Source: British Journal of Ophthalmology - November 14, 2014 Category: Opthalmology Authors: Vehof, J., Kozareva, D., Hysi, P. G., Hammond, C. J. Tags: Lens and zonules, Press releases, Neurology Original articles - Clinical science Source Type: research

Risk Factors for Falls in Older Korean Adults: The 2011 Community Health Survey.
In conclusion, age, female sex, marital status, residence location, self-rated health, stress, and several chronic conditions were significantly associated with the risk for falls in the older Korean adults. Our findings suggest that these risk factors should be addressed in public health policies for preventing falls. GRAPHICAL ABSTRACT: PMID: 25408578 [PubMed - as supplied by publisher]
Source: J Korean Med Sci - November 1, 2014 Category: Journals (General) Authors: Choi EJ, Kim SA, Kim NR, Rhee JA, Yun YW, Shin MH Tags: J Korean Med Sci Source Type: research

Risk-Benefit Profiles of Women Using Tamoxifen for Chemoprevention
Conclusions: While the majority of women who used tamoxifen for primary prevention of breast cancer were likely to benefit, substantial discontinuation of tamoxifen before five years and use by women at risk of serious side effects may attenuate benefits for breast cancer prevention.
Source: JNCI - December 3, 2014 Category: Cancer & Oncology Authors: Nichols, H. B., DeRoo, L. A., Scharf, D. R., Sandler, D. P. Tags: Article Source Type: research

An Unusual Case Of Cadasil With Occipital Lobe Involvement (P6.006)
CONCLUSION: We discuss the unique features of a rare case of occipital lobe predominant CADASIL lacking the typical anterior temporal lobe involvement. This case exemplifies the heterogeneity of clinical findings that may be associated with NOTCH3 mutations.Disclosure: Dr. Mishra has nothing to disclose. Dr. Rao has nothing to disclose. Dr. Flippen has received personal compensation for activities with MAP Pharmaceuticals/Allergan. Dr. Flippen has received personal compensation in an editorial capacity for the Journal of Graduate Medical Education and Up-To-Date. Dr. Flippen has received Dr. Fogel has received personal com...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Mishra, S., Rao, N., Flippen, C., Fogel, B., Hathout, G., Thomas, M., Kattan, J., Trikamji, B. Tags: Treatments, Therapeutics, and Biomarkers Poster Discussion Session Source Type: research

The effect of blue-blocking intraocular lenses on circadian biological rhythm: protocol for a randomised controlled trial (CLOCK-IOL colour study)
Introduction Blue light information plays an important role in synchronising internal biological rhythm within the external environment. Circadian misalignment is associated with the increased risk of sleep disturbance, obesity, diabetes mellitus, depression, ischaemic heart disease, stroke and cancer. Meanwhile, blue light causes photochemical damage to the retina, and may be associated with age-related macular degeneration (AMD). At present, clear intraocular lenses (IOLs) and blue-blocking IOLs are both widely used for cataract surgery; there is currently a lack of randomised controlled trials to determine whether clear...
Source: BMJ Open - May 12, 2015 Category: Journals (General) Authors: Nishi, T., Saeki, K., Obayashi, K., Miyata, K., Tone, N., Tsujinaka, H., Yamashita, M., Masuda, N., Mizusawa, Y., Okamoto, M., Hasegawa, T., Maruoka, S., Ueda, T., Kojima, M., Matsuura, T., Kurumatani, N., Ogata, N. Tags: Open access, Epidemiology, Ophthalmology Protocol Source Type: research

Long-term health of vegetarians & vegans
The Nutrition Society Paper of the Month for February is from Proceedings of the Nutrition Society and is entitled 'The long-term health of vegetarians and vegans'.  The study findings were presented at the 2015 Summer Conference on ‘The future of animal products in the human diet: health and environmental concerns’ during symposium three which focused on alternatives to meat.  Vegetarians are defined as people who do not eat any meat, poultry or fish. They may be sub-classified as lacto-ovo-vegetarians who eat dairy products and/or eggs and vegans who do not eat any animal products. Although vegetarians represent...
Source: The Nutrition Society - February 16, 2016 Category: Nutrition Authors: Cassandra Ellis Source Type: news

Id: 64: reversible blindness associated with diabetic ketoacidosis: a rare combination
Discussion Sudden painless vision loss has a wide differential diagnosis and it is usually caused by ischemia at retinal, ocular or cortical level. No history of methanol ingestion or trauma, normal fundoscopy, normal MRI and rapid return of vision after correction of diabetic ketoacidosis strongly suggests that blindness was related to acidosis. Alcoholic ketoacidosis has been reported to cause transient reversible blindness in other case reports and correction of acidosis lead to reversal of blindness. Other rare causes of reversible blindness include posterior reversible encephalopathy syndrome, brain tumors, anterior i...
Source: Journal of Investigative Medicine - March 21, 2016 Category: Research Authors: Asad, Z., Chaudhary, A., Awab, A. Tags: Pulmonary/Critical Care Source Type: research

Long-term health of vegetarians & vegans
The Nutrition Society Paper of the Month for February is from Proceedings of the Nutrition Society and is entitled 'The long-term health of vegetarians and vegans'.  The study findings were presented at the 2015 Summer Conference on ‘The future of animal products in the human diet: health and environmental concerns’ during symposium three which focused on alternatives to meat.  Vegetarians are defined as people who do not eat any meat, poultry or fish. They may be sub-classified as lacto-ovo-vegetarians who eat dairy products and/or eggs and vegans who do not eat any animal products. Although vegetarians represent...
Source: The Nutrition Society - February 16, 2016 Category: Nutrition Authors: Cassandra Ellis Source Type: news

Qualitative and quantitative analyses of stroke dynamics and microfluidics of phacoemulsification probes operating in different modes
To compare phacoemulsification (phaco) tip movement, microfluidic dynamics, and tip-to-load interaction between longitudinal, torsional, and elliptical ultrasound (US) modalities.
Source: Journal of Cataract and Refractive Surgery - April 30, 2016 Category: Opthalmology Authors: Jaime Zacharias Tags: Laboratory science Source Type: research

Long-term health of vegetarians & vegans
The Nutrition Society Paper of the Month for February is from Proceedings of the Nutrition Society and is entitled ' The long-term health of vegetarians and vegans ' .   The study findings were presented at the 2015 Summer Conference on ‘The future of animal products in the human diet: health and environmental concerns’ during symposium three which focused on alternatives to meat.  Vegetarians are defined as people who do not eat any meat, poultry or fish. They may be sub-classified as lacto-ovo-vegetarians who eat dairy products and/or eggs and vegans who do not eat any animal products. Although vegetarians re...
Source: The Nutrition Society - February 16, 2016 Category: Nutrition Authors: Cassandra Ellis Source Type: news