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Condition: Pain

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Total 6188 results found since Jan 2013.

Developments in treating the nonmotor symptoms of stroke.
Authors: Hillis AE Abstract Introduction: Stroke is among the most common causes of disability worldwide. Nonmotor symptoms of stroke are common and disabling. Many are treatable, and intervention improves the quality of life for stroke survivors.Areas covered: Here the author summarizes evidence-based treatment of depression and other mood disorders, aphasia, hemispatial neglect, impairments of emotional communication and empathy, deficits in memory and other cognitive functions, sleep disorders, pain, fatigue, (1)and seizures resulting from stroke. The author focuses on treatments supported by randomized controlled ...
Source: Expert Review of Neurotherapeutics - May 5, 2020 Category: Neurology Tags: Expert Rev Neurother Source Type: research

Opioids in Post-stroke Pain: A Systematic Review and Meta-Analysis
Conclusions: The limited number of the included studies and their heterogeneity in terms of study design do not support the efficacy of opioids in post-stroke pain and in pain-related outcomes. Large double-blind randomized clinical trials with objective assessment of pain and related symptoms are needed to further investigate this topic.
Source: Frontiers in Pharmacology - November 27, 2020 Category: Drugs & Pharmacology Source Type: research

Neurosteroids: a novel promise for the treatment of stroke and post ‐stroke complications
AbstractStroke is the primary reason for death and disability worldwide, with few treatment strategies to date. Neurosteroids, which are natural molecules in the brain, have aroused great interest in the field of stroke. Neurosteroids are a kind of steroid that acts on the nervous system, and are synthesized in the mitochondria of neurons or glial cells using cholesterol or other steroidal precursors. Neurosteroids mainly include estrogen, progesterone (PROG), allopregnanolone, dehydroepiandrosterone (DHEA), and vitamin D (VD). Most of the preclinical studies have confirmed that neurosteroids can decrease the risk of strok...
Source: Journal of Neurochemistry - September 5, 2021 Category: Neuroscience Authors: Jiawei Xu, Yunxiang Zhou, Caochong Yan, Xiaoyu Wang, Jianyao Lou, Yi Luo, Shiqi Gao, Junjie Wang, Liang Wu, Xiangfu Gao, Anwen Shao Tags: REVIEW ARTICLE Source Type: research

Intra-rater and inter-rater reliability of pressure pain threshold assessment in stroke patients
CONCLUSIONS: PPT assessment with good or excellent reliability can be used in stroke patients. Neither of the two sides (affected or unaffected) affects PPT reliability, and intra-rater reliability is better than inter-rater reliability. In addition, gender, stroke type, and motor function can affect the reliability of measuring mechanical pain threshold in post-stroke survivors.CLINICAL REHABILITATION IMPACT: The pressure algometer can be used as a reliable and portable tool to assess the mechanical pain tolerance and sensory function in stroke patients in clinics.PMID:35362718 | DOI:10.23736/S1973-9087.22.07378-6
Source: European Journal of Physical and Rehabilitation Medicine - April 1, 2022 Category: Rehabilitation Authors: Yong-Hui Zhang Yu-Chen Wang Gong-Wei Hu Xiao-Qin Ding Xiao-Hua Shen Hui Yang Ji-Feng Rong Xue-Qiang Wang Source Type: research

Short-term stroke risk after emergency department treat-and-release headache visit
CONCLUSION: Approximately 1 in 700 patients discharged to home from the ED with a headache diagnosis had a stroke in the following month. Stroke risk was three to four times higher after an ED visit for headache compared to renal colic or back pain.PMID:36073865 | DOI:10.1111/head.14387
Source: Headache - September 8, 2022 Category: Neurology Authors: Ava L Liberman Cenai Zhang Richard B Lipton Hooman Kamel Neal S Parikh Babak B Navi Alan Z Segal Junaid Razzak David E Newman-Toker Alexander E Merkler Source Type: research