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Stroke death in patients receiving radiation for head and neck cancer in the modern era
ConclusionsWhile radiotherapy for head and neck cancer increases the hazard of stroke death, this is reduced in the modern era and remains a very small absolute risk.
Source: Frontiers in Oncology - June 15, 2023 Category: Cancer & Oncology Source Type: research

Is stroke incidence increased in survivors of adult cancers? A systematic review and meta-analysis
ConclusionsStroke incidence is significantly increased after diagnosis of certain cancers.Implications for Cancer SurvivorsCardiovascular risk should be assessed during cancer survivorship care, with attention to modifying shared cancer/cardiovascular risk factors.
Source: Journal of Cancer Survivorship - November 5, 2021 Category: Cancer & Oncology Source Type: research

Cancer and Cerebrovascular Disease
AbstractPurpose of ReviewTo review the latest information about the interactions between cancer and cerebrovascular disease.Recent FindingsAdditional data support the finding that both ischemic and hemorrhagic stroke are important complications of cancer or its treatment. Reperfusion therapy is being given successfully to patients with stroke complicating cancer.SummaryHemorrhagic stroke may occur with metastatic disease to the brain, coagulopathies from cancer, in particular leukemia, or as complications of chemotherapy. Ischemic stroke also may be a complication of metastatic disease with local invasion of vessels, a pro...
Source: Current Neurology and Neuroscience Reports - August 22, 2019 Category: Neuroscience Source Type: research

Dementia Risk in Irradiated Patients With Head and Neck Cancer
This study estimated the dementia risk associated with different treatment modalities in a head and neck cancer population with long-term follow-up. Taiwan's National Health Insurance claims database and a cancer registry database from the Collaboration Center of Health Information Application were linked for the present analysis. Patients with head and neck cancer, treated from January 1, 2002 to December 31, 2010, were included in the study. The follow-up duration was the period from the index date to December 31, 2012. Inclusion criteria were head and neck cancer; an age>20 years; and having undergone surgery, CT, concu...
Source: Medicine - November 1, 2015 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Cardiac comorbidity in head and neck cancer patients and its influence on cancer treatment selection and mortality: a prospective cohort study
AbstractComorbidity assessment and a profound cardiac examination were implemented into pre-treatment diagnostics to analyze their influence on head and neck squamous cell carcinoma (HNSCC) therapy selection and short-term mortality. Comorbidity was measured prospectively in 49 HNSCC patients using standard indices between 2012 and 2013. Cardiac examinations included electrocardiogram, echocardiography, and bicycle ergometry. Most patients had stage IV tumors (61  %), smoked (61 %), and showed alcohol abuse (57 %); 38 patients (78 %) received a multimodal therapy; 65 % had an adult comorbidity evaluation 27 index ≥2...
Source: European Archives of Oto-Rhino-Laryngology - August 4, 2016 Category: ENT & OMF Source Type: research

Neurologic manifestations of geriatric patients with cancer (P6.188)
Conclusions:Neurologic manifestations are reported in about 40% of patients with cancer, approximately half of living patients with cancer are over 65 years of age, this increase merits the medical and related personnel to be prepared and recognize, diagnose and treat this highly morbid conditions. Neurologic manifestations and diagnoses in patients with cancer are different in the elderly and should be treated individually; the present work offers information regarding clinical symptoms and neurologic diagnoses in this population.Disclosure: Dr. Cacho Diaz has nothing to disclose. Dr. Lorenzana-Mendoza has nothing to disc...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Diaz, B. C., Lorenzana-Mendoza, N., Soto, G. R., Gomez, A. H. Tags: Neurologic Complications of Cancer Source Type: research

Juvenile melanomas: Western Australian Melanoma Advisory Service experience
ConclusionsJuvenile melanoma remains a rarity in Western Australia despite a very high incidence of adult melanoma. Unlike in adults, no definitive risk factors have been established. A significant proportion of this cohort had a pre‐existing naevus and while most melanomas occurred in sun‐exposed areas in light‐skinned individuals the association between sunburn and melanoma was not strong.
Source: Australasian Journal of Dermatology - May 1, 2017 Category: Dermatology Authors: Jie Xin Xu, Sharnice Koek, Samantha Lee, Mark Hanikeri, Mark Lee, Trevor Beer, Christobel Saunders Tags: Original Research Source Type: research

Juvenile melanomas: Western Australian Melanoma Advisory Service experience.
CONCLUSIONS: Juvenile melanoma remains a rarity in Western Australia despite a very high incidence of adult melanoma. Unlike in adults, no definitive risk factors have been established. A significant proportion of this cohort had a pre-existing naevus and while most melanomas occurred in sun-exposed areas in light-skinned individuals the association between sunburn and melanoma was not strong. PMID: 28809039 [PubMed - as supplied by publisher]
Source: The Australasian Journal of Dermatology - August 15, 2017 Category: Dermatology Authors: Xu JX, Koek S, Lee S, Hanikeri M, Lee M, Beer T, Saunders C Tags: Australas J Dermatol Source Type: research