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Total 403 results found since Jan 2013.

Influence of continuous positive airway pressure treatment on auditory event-related potentials p300
Acta Clin Croat. 2022 Nov;61(3):373-378. doi: 10.20471/acc.2022.61.03.01.ABSTRACTObstructive sleep apnea (OSA) is a sleep-related breathing disorder characterized by obstructions of the upper airway during sleep, resulting in repetitive breathing pauses accompanied by oxygen desaturation and arousal from sleep. OSA can be successfully treated with continuous positive airway pressure (CPAP), weight loss, positional therapy, oral appliances, hypoglossal nerve stimulation, and surgical procedures. It has been observed that untreated OSA is related to chronic disorders including hypertension, arrhythmias, congestive heart fail...
Source: Acta Clinica Croatica - July 26, 2023 Category: General Medicine Authors: Jelena Šarić-Jurić Stjepan Juri ć Ivana Markovi ć Source Type: research

7 Myths About Cholesterol, Debunked
You may not recall every lab value from your last physical, but you probably remember one: Your cholesterol level. If it’s higher than ideal, you’re not alone. According to the U.S. Centers for Disease Control and Prevention, between 2015 and 2018, almost 12% of U.S. adults ages 20 and up had high total cholesterol, defined as above 240 mg/dL. The type that physicians mostly worry about is LDL (or “bad”) cholesterol, which is one component of that total. Why do doctors care so much about cholesterol? First, “it predicts risk,” says Dr. Jeffrey Berger, a cardiologist and director of the C...
Source: TIME: Health - June 19, 2023 Category: Consumer Health News Authors: Katherine Hobson Tags: Uncategorized freelance healthscienceclimate heart health Source Type: news

Melatonin mitigates type 1 diabetes ‐aggravated cerebral ischemia‐reperfusion injury through anti‐inflammatory and anti‐apoptotic effects
ConclusionsT1DM aggravates CIRI. Melatonin treatment is neuroprotective against CIRI in T1DM rats via anti-inflammatory and anti-apoptotic effects.
Source: Brain and Behavior - June 16, 2023 Category: Neurology Authors: Qian Xu, Raymond Tak Fai Cheung Tags: ORIGINAL ARTICLE Source Type: research

Haematoloechus sp. attachment shifts endothelium in vivo from pro- to anti-inflammatory profile in Rana pipiens: evidence from systemic and capillary physiology
Am J Physiol Regul Integr Comp Physiol. 2023 Jun 5. doi: 10.1152/ajpregu.00041.2023. Online ahead of print.ABSTRACTThis prospective, descriptive study focused on lung flukes (Haematoloechus sp., H) and their impact on systemic and individual capillary variables measured in pithed Rana pipiens, a long-standing model for studies of capillary physiology. Three groups were identified based on H attachment: no Haematoloechus (No H), Haematoloechus not attached (H Not Att), and Haematoloechus attached (H Att). Among 38 descriptive, cardiovascular, and immunological variables, 18 changed significantly with H. Symptoms of H includ...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - June 5, 2023 Category: Physiology Authors: Donna A Williams Mary H Flood Source Type: research

Amino acid solution mitigates hypothermia response and intestinal damage following exertional heat stroke in male mice
Exertional heat stroke (EHS) is a debilitating and potentially fatal condition for which few prevention strategies exist. These results suggest that a 5AAS improves Tc regulation during EHS recovery through maintaining mucosal function and integrity and that protecting the GI tract during EHS may be beneficial in some of the health consequences of EHS exposure. AbstractIncreased gut permeability is implicated in the initiation and extent of the cytokine inflammatory response associated with exertional heat stroke (EHS). The primary objective of this study was to determine if a five amino acid oral rehydration solution (5AA...
Source: Physiological Reports - May 23, 2023 Category: Physiology Authors: Michelle A. King, Astrid Grosche, Shauna M. Ward, Jermaine A. Ward, Anusree Sasidharan, Thomas A. Mayer, Mark L. Plamper, Xiaodong Xu, Matthew D. Ward, Thomas L. Clanton, Sadasivan Vidyasagar Tags: ORIGINAL ARTICLE Source Type: research

Inflammation May Be the Culprit Behind Our Deadliest Diseases
In the early days of my medical residency, I met a man whom we’ll call Jason. He arrived to our emergency room on a holiday, nonchalant yet amiable, and complained of mild chest pain. Jason was tall and trim, with a strong South Boston accent and fingertips still faintly stained from his last home-improvement project. He was only 45 years old, but he looked much younger. He didn’t smoke, barely drank alcohol, and his cholesterol levels had always been normal. No one in his family had a history of heart disease. He asked us if we could work quickly—he wanted to be home for dinner with his daughters. [time-...
Source: TIME: Health - April 11, 2023 Category: Consumer Health News Authors: Shilpa Ravella Tags: Uncategorized freelance health Source Type: news

Prevention of Cardiovascular Events in Patients With Chronic Kidney Disease
CONCLUSIONS: Patients diagnosed with chronic kidney disease have markedly increased risk of cardiovascular events, including myocardial infarction, stroke, heart failure, and cardiovascular death. However, until recently, there were few cardiovascular outcome studies that targeted enrollment specifically to those patients. Certain drugs now have shown benefits to cardiovascular end points in this population.PMID:37029538 | DOI:10.1177/10600280231165774
Source: The Annals of Pharmacotherapy - April 8, 2023 Category: Drugs & Pharmacology Authors: Chris M Terpening Source Type: research