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Nutrition: Vitamin C

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Total 73 results found since Jan 2013.

Effects of vitamin C stimulation on rehabilitation of dysphagia after stroke: a randomized trial
CONCLUSION: Vitamin C acid stimulation significantly improves rehabilitation of stroke patients with dysphagia, and ameliorates the nutritional status and immune function of patients.PMID:35362717 | DOI:10.23736/S1973-9087.22.07337-3
Source: European Journal of Physical and Rehabilitation Medicine - April 1, 2022 Category: Rehabilitation Authors: Jiongmei Wang E Chang Yujuan Jiang Source Type: research

High-Dose Vitamin C Prevents Secondary Brain Damage After Stroke via Epigenetic Reprogramming of Neuroprotective Genes
AbstractVitamin C has recently been identified as an epigenetic regulator by activating ten-eleven translocases (TETs), enzymes involved in generating DNA hydroxymethylcytosine (5hmC). Currently, we investigated whether high-dose vitamin C promotes neuroprotection through epigenetic modulation of 5hmC, if there are sex-specific differences in outcome, and the therapeutic potential of vitamin C in stroke-related comorbidities in adult mice. Post-stroke treatment with ascorbate (reduced form), but not dehydroascorbate (oxidized form), increased TET3 activity and 5hmC levels and reduced infarct following focal ischemia. Hydro...
Source: Translational Stroke Research - March 20, 2022 Category: Neurology Source Type: research

The impact of plasma vitamin C levels on the risk of cardiovascular diseases and Alzheimer's disease: a Mendelian randomization study
Previous observational studies have reported associations between plasma vitamin C levels, and cardiovascular diseases (CVDs) and Alzheimer's disease (AD); however, no conclusive results have been obtained. We conducted a Mendelian randomization (MR) study to investigate the causality of vitamin C on the risk of nine CVDs [including coronary artery disease (CAD), myocardial infarction (MI), atrial fibrillation (AF), heart failure (HF), stroke, ischemic stroke (IS), and IS subtypes] and Alzheimer's disease.
Source: Clinical Nutrition - September 4, 2021 Category: Nutrition Authors: Lu Chen, Xingang Sun, Zhen Wang, Yunlong Lu, Miao Chen, Yuxian He, Hongfei Xu, Liangrong Zheng Tags: Original article Source Type: research

Vitamin C and scar strength: analysis of a historical trial and implications for collagen-related pathologies
Am J Clin Nutr. 2021 Aug 16:nqab262. doi: 10.1093/ajcn/nqab262. Online ahead of print.ABSTRACTA double-blind controlled trial initiated in 1944 has led to the common narrative that a 10-mg daily vitamin C intake is adequate to prevent and treat impaired wound healing, and by inference, other collagen-related diseases such as heart disease or stroke. The WHO relies on this narrative to set the recommended nutrient intake for vitamin C. This narrative, however, is based on what is known as the eyeball method of data assessment. The 1944 trial published individual participant data on scar strength providing an opportunity to ...
Source: The American Journal of Clinical Nutrition - August 16, 2021 Category: Nutrition Authors: Philippe P Hujoel Margaux L A Hujoel Source Type: research