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Associations of Dietary Intakes of Vitamins B1 and B3 with Risk of Mortality from Cardiovascular Disease among Japanese Men and Women: the Japan Collaborative Cohort Study
CONCLUSIONS: Higher dietary intakes of vitamins B1 and B3 were inversely associated with mortality from ischemic heart disease and a higher dietary intake of vitamin B1 was inversely associated with a reduced risk of mortality from heart failure among Japanese men and women.PMID:35466893 | DOI:10.1017/S0007114522001209
Source: The British Journal of Nutrition - April 25, 2022 Category: Nutrition Authors: Chengyao Tang Ehab S Eshak Kokoro Shirai Akiko Tamakoshi Hiroyasu Iso Source Type: research

Wernicke ’s encephalopathy and cranial nerve VII palsy in a 24-year-old patient with COVID-19
ConclusionsThis case is one of three documented cases of Wernicke ’s encephalopathy believed to be caused by COVID-19 in patients without risk factors or chronic alcohol use. Ours is also the first case in which Wernicke’s encephalopathy presents with a concomitant cranial nerve VII palsy. While Emergency Medicine doctors must maintain a high index of suspicio n for stroke in younger patients with COVID-19, our patient’s case augments the correlation between COVID-19 and Wernicke’s encephalopathy in patients without other risk factors for developing the syndrome.
Source: International Journal of Emergency Medicine - January 28, 2022 Category: Emergency Medicine Source Type: research

Bioinformatic Analysis of Exosomal MicroRNAs of Cerebrospinal Fluid in Ischemic Stroke Rats After Physical Exercise
Neurochem Res. 2021 Mar 11. doi: 10.1007/s11064-021-03294-1. Online ahead of print.ABSTRACTPhysical exercise is beneficial to the structural and functional recovery of post-ischemic stroke, but its molecular mechanism remains obscure. Herein, we aimed to explore the underlying mechanism of exercise-induced neuroprotection from the perspective of microRNAs (miRNAs). Adult male Sprague-Dawley (SD) rats were randomly distributed into 4 groups, i.e., the physical exercise group with the transient middle cerebral artery occlusion (tMCAO) surgery (PE-IS, n = 28); the physical exercise group without tMCAO surgery (PE, n = 6); the...
Source: Neurochemical Research - March 12, 2021 Category: Neuroscience Authors: Mudan Huang Chongjun Xiao Liying Zhang Lili Li Jing Luo Lilin Chen Xiquan Hu Haiqing Zheng Source Type: research

Reduced thiamine is a predictor for cognitive impairment of cerebral infarction
ConclusionsReduced thiamine is one of the predictors for early cognitive impairment in patients with acute cerebral infarction.
Source: Brain and Behavior - August 4, 2020 Category: Neurology Authors: Liang Feng, Weilei He, Guiqian Huang, Shasha Lin, Chengxiang Yuan, Haoran Cheng, Jincai He, Yiming Liu Tags: ORIGINAL RESEARCH Source Type: research

Alcoholic cardiomyopathy : The result of dosage and individual predisposition.
Authors: Maisch B Abstract The individual amount of alcohol consumed acutely or chronically decides on harm or benefit to a person's health. Available data suggest that one to two drinks in men and one drink in women will benefit the cardiovascular system over time, one drink being 17.6 ml 100 % alcohol. Moderate drinking can reduce the incidence and mortality of coronary artery disease, heart failure, diabetes, ischemic and hemorrhagic stroke. More than this amount can lead to alcoholic cardiomyopathy, which is defined as alcohol toxicity to the heart muscle itself by ethanol and its metabolites. Historical exa...
Source: Herz - September 3, 2016 Category: Cardiology Tags: Herz Source Type: research

Thiamine Deficiency While on Total Parenteral Nutrition Mimicking Acute Stroke: A Case Report (P3.217)
CONCLUSIONS: Thiamine deficiency mimicking stroke while on total parenteral nutrition has been rarely documented. Recognition of this syndrome is critical as prompt treatment may reverse symptoms.Disclosure: Dr. Parker has nothing to disclose. Dr. Marafie has nothing to disclose. Dr. Wolf has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Parker, A., Marafie, D., Wolf, V. Tags: Neurocritical Care: Clinical Science and Therapeutics Source Type: research

A Case of Transient Global Amnesia: A Review and How It May Shed Further Insight into the Neurobiology of Delusions
Conclusion In closing, our patient’s episode of TGA combined with her emotional and perceptual response lends credence to the proposal of a “fear/paranoia” circuit in the genesis of paranoid delusions—a circuit incorporating amygdala, frontal, and parietal cortices. Here, neutral or irrelevant stimuli, thoughts, and percepts come to engender fear and anxiety, while dysfunction in frontoparietal circuitry engenders inappropriate social predictions and maladaptive inferences about the intentions of others.[54] Hippocampus relays information about contextual information based on past experiences and the current situat...
Source: Innovations in Clinical Neuroscience - April 1, 2016 Category: Neuroscience Authors: ICN Online Editor Tags: Anxiety Disorders Behavioral and Cognitive Neurology Case Report Cognition Current Issue Dementia Medical Issues Neurologic Systems and Symptoms Psychiatry Schizophrenia delusions hippocampus neurobiology Transient global amnesia Source Type: research

Fluctuating Mental Status and Fever of Unknown Origin (P1.030)
Conclusion: Central nervous system involvement as the initial manifestation of microscopic polyangiitis is rare and can result in a challenging clinical picture including recurrent ischemic strokes.Disclosure: Dr. Daniel has nothing to disclose. Dr. Brink has nothing to disclose. Dr. Hosley has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Daniel, A., Brink, J., Hosley, C. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Quadri-chamber cardiac thrombi in alcoholic cardiomyopathy: a rare though ominous finding
We report a case of alcoholic cardiomyopathy with an alarming finding of thrombi in all cardiac chambers. Echocardiographic evidence of quadri-chamber intracardiac thrombi has rarely been described in the literature. Case A 48-year-old man with history of chronic alcoholism presented with progressive breathlessness of 1 year's duration. Cardiovascular examination showed sinus tachycardia and evidence of congestive cardiac failure. A transthoracic echocardiogram (TTE) showed dilated cardiac chambers, severe biventricular global dysfunction with an alarming finding of thrombi...
Source: Postgraduate Medical Journal - July 16, 2013 Category: Journals (General) Authors: Singh, Y., Singla, V., Singh, B., Rajendran, R., Khandenahally, R. S., Manjunath, C. N. Tags: Cardiomyopathy, Immunology (including allergy), Drugs: cardiovascular system, Echocardiography, Heart failure, Stroke, Hypertension, Malnutrition, Interventional cardiology, Ischaemic heart disease, Venous thromboembolism, Alcohol-related disorders, Drugs Source Type: research