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Nutrition: Selenium
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Total 69 results found since Jan 2013.
Characterization of Selenium Compounds for Anti-ferroptotic Activity in Neuronal Cells and After Cerebral Ischemia –Reperfusion Injury
AbstractThe emergence of ferroptosis as a cell death pathway associated with brain disorders including stroke and neurodegenerative diseases emphasizes the need to develop therapeutics able to target the brain and to protect neurons from ferroptotic death. Selenium plays an essential role in reducing lipid peroxidation generated during ferroptosis through its incorporation into the catalytic site of glutathione peroxidase 4. Here, we compared the anti-ferroptotic activity of several organic and inorganic selenium compounds: methylselenocysteine, selenocystine, selenomethionine, selenocystamine, ebselen, sodium selenite, an...
Source: Neurotherapeutics - September 8, 2021 Category: Neurology Source Type: research
Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults
CONCLUSIONS: The study indicated that several plasma metals/metalloids were key determinants and predictors of all-cause and CVD death in the Chinese population. Our findings highlighted the importance to comprehensively assess and monitor multiple metals/metalloids exposures.PMID:34365319 | DOI:10.1016/j.envint.2021.106808
Source: Environment International - August 8, 2021 Category: Environmental Health Authors: Limei Shi Yu Yuan Yang Xiao Pinpin Long Wending Li Yanqiu Yu Yiyi Liu Kang Liu Hao Wang Lue Zhou Handong Yang Xiulou Li Meian He Tangchun Wu Source Type: research
Selenium attenuates ischemia/reperfusion injury ‑induced damage to the blood‑brain barrier in hyperglycemia through PI3K/AKT/mTOR pathway‑mediated autophagy inhibition
In conclusion, the present findings indicated that selenium can inhibit autophagy by regulating the PI3K/AKT/mTOR signaling pathway, significantly preventing BBB damage following cerebral I/R injury in hyperglycemic conditions.PMID:34296284 | DOI:10.3892/ijmm.2021.5011
Source: International Journal of Molecular Medicine - July 23, 2021 Category: Molecular Biology Authors: Biao Yang Yaqiong Li Yanmei Ma Xiaopeng Zhang Lan Yang Xilin Shen Jianzhong Zhang Li Jing Source Type: research
Sex difference in the association between plasma selenium and first stroke: a community-based nested case-control study
ConclusionOur study indicated a significant,non-linear, negative association between plasma selenium and first stroke in males but not in females.Trial registrationChiCTR1800017274.
Source: Biology of Sex Differences - May 29, 2021 Category: Biology Source Type: research
Relationship between the Circulating Selenium Level and Stroke: A Meta-Analysis of Observational Studies
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Source: Journal of the American College of Nutrition - March 30, 2021 Category: Nutrition Authors: Jun Ding Yi Zhang Source Type: research
A cross-sectional study of blood selenium concentration and cognitive function in elderly Americans: National Health and Nutrition Examination Survey 2011-2014.
Conclusions: Higher blood selenium is associated with higher cognitive scores in elderly Americans.
PMID: 33050724 [PubMed - as supplied by publisher]
Source: Annals of Human Biology - October 21, 2020 Category: Biology Tags: Ann Hum Biol Source Type: research
Supplemental Vitamins and Minerals for Cardiovascular Disease Prevention and Treatment
The objective of this study is to explore the current literature supporting the use oral multivitamins and multi/minerals (OMVMs) for cardiovascular diseases (CVD) treatment and prevention.Recent FindingsData on multivitamins, vitamin C and D, coenzyme Q, calcium, and selenium, has showed no consistent benefit for the prevention of CVD, myocardial infarction, or stroke, nor was there a benefit for all-cause mortality to support their routine supplementation. Folic acid alone and B vitamins with folic acid, B6 and B12, reduce stroke, whereas niacin and antioxidants are associated with an increased risk of all-cause mortalit...
Source: Current Cardiology Reports - February 13, 2020 Category: Cardiology Source Type: research
