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Nutrition: Probiotics
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Total 114 results found since Jan 2013.
Probiotics Bring New Hope for Atherosclerosis Prevention and Treatment
Oxid Med Cell Longev. 2022 Sep 24;2022:3900835. doi: 10.1155/2022/3900835. eCollection 2022.ABSTRACTCardiovascular disease is the leading cause of human mortality and morbidity worldwide. Atherosclerosis (AS) is the underlying pathological responsible in most acute and severe cardiovascular diseases including myocardial infarction and stroke. However, current drugs applied to the treatment of AS are not clinically effective, and there is a large residual risk of cardiovascular disease and multiple side effects. Increasing evidence supports a close relationship between microorganisms and the incidence of AS. Recent data hav...
Source: Atherosclerosis - October 4, 2022 Category: Cardiology Authors: Taiyu Zhai Pingping Wang Xiumei Hu Lei Zheng Source Type: research
Indole-3-propionic acid alleviates ischemic brain injury in a mouse middle cerebral artery occlusion model
Exp Neurol. 2022 Apr 8:114081. doi: 10.1016/j.expneurol.2022.114081. Online ahead of print.ABSTRACTIncreasing evidence highlights the importance of gut microbiota and its metabolites as an environmental factor affecting ischemic stroke. However, the role of microbial indole metabolites in ischemic stroke remains largely unknown. Here, we evaluated the effects and the underlying mechanism of indole-3-propionic acid (IPA) in a mouse model of acute middle cerebral artery occlusion (MCAO) and the mechanisms underlying these effects. We collected blood samples and evaluated serum indole derivatives levels using ultra-performanc...
Source: Experimental Neurology - April 11, 2022 Category: Neurology Authors: Yu Xie Xiaoxiong Zou Jianbang Han Zhongfei Zhang Zhiming Feng Qian Ouyang Shiting Hua Zhizheng Liu Cong Li Yingqian Cai Yuxi Zou Yanping Tang Xiaodan Jiang Source Type: research
The Bridge Between Ischemic Stroke and Gut Microbes: Short-Chain Fatty Acids
Cell Mol Neurobiol. 2022 Mar 28. doi: 10.1007/s10571-022-01209-4. Online ahead of print.ABSTRACTShort-chain fatty acids (SCFAs) are monocarboxylates produced by the gut microbiota (GM) and result from the interaction between diet and GM. An increasing number of studies about the microbiota-gut-brain axis (MGBA) indicated that SCFAs may be a crucial mediator in the MGBA, but their roles have not been fully clarified. In addition, there are few studies directly exploring the role of SCFAs as a potential regulator of microbial targeted interventions in ischemic stroke, especially for clinical studies. This review summarizes t...
Source: Cellular and Molecular Neurobiology - March 29, 2022 Category: Cytology Authors: Zongwei Fang Mingrong Chen Jiafen Qian Chunhua Wang Jinhua Zhang Source Type: research
< em > Bifidobacterium breve < /em > and < em > Bifidobacterium longum < /em > Attenuate Choline-Induced Plasma Trimethylamine N-Oxide Production by Modulating Gut Microbiota in Mice
Nutrients. 2022 Mar 14;14(6):1222. doi: 10.3390/nu14061222.ABSTRACTAtherosclerosis is the main cause of myocardial infarction and stroke, and the morbidity and mortality rates of cardiovascular disease are among the highest of any disease worldwide. Excessive plasma trimethylamine-N-oxide (TMAO), an intestinal metabolite, promotes the development of atherosclerosis. Therefore, effective measures for reducing plasma TMAO production can contribute to preventing atherosclerosis. Probiotics are living microorganisms that are beneficial to the human body, and some of them can attenuate plasma TMAO production. To explore the eff...
Source: Atherosclerosis - March 26, 2022 Category: Cardiology Authors: Qianqian Wang Min Guo Yang Liu Mengshu Xu Liuting Shi Xiu Li Jianxin Zhao Hao Zhang Gang Wang Wei Chen Source Type: research
Integrated Analysis of the Cecal Microbiome and Plasma Metabolomics to Explore NaoMaiTong and Its Potential Role in Changing the Intestinal Flora and Their Metabolites in Ischemic Stroke
Ischemic stroke (IS), as a leading cause of disability worldwide, affects intestinal bacterial communities and their metabolites, while recent discoveries have highlighted the importance of the intestinal microflora in the development of IS. Systematic investigations of complex intestinal bacterial communities and their metabolites during ischemic brain injury contribute to elucidate the promising therapeutic targets for IS. However, the associations between intestinal microbiota and related circulating metabolic processes in IS remained unclear. Hence, to identify the changed microflora and their metabolites in IS of NaoM...
Source: Frontiers in Pharmacology - January 20, 2022 Category: Drugs & Pharmacology Source Type: research
A Comprehensive Review on the Role of the Gut Microbiome in Human Neurological Disorders
Clin Microbiol Rev. 2022 Jan 5;35(1):e0033820. doi: 10.1128/CMR.00338-20. Online ahead of print.ABSTRACTThe human body is full of an extensive number of commensal microbes, consisting of bacteria, viruses, and fungi, collectively termed the human microbiome. The initial acquisition of microbiota occurs from both the external and maternal environments, and the vast majority of them colonize the gastrointestinal tract (GIT). These microbial communities play a central role in the maturation and development of the immune system, the central nervous system, and the GIT system and are also responsible for essential metabolic pat...
Source: Clinical Microbiology Reviews - January 5, 2022 Category: Microbiology Authors: Shokufeh Ghasemian Sorboni Hanieh Shakeri Moghaddam Reza Jafarzadeh-Esfehani Saman Soleimanpour Source Type: research
