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Fish, Cardiovascular Disease, and Mortality
Fish and shellfish (hereafter referred to as fish) are major sources of the dietary long-chain ω-3 fatty acids eicosapentaenoic acid (20:5n-3) and docosahexaenoic acid (22:6n-3) and also contain other nutrients, such as vitamin D, riboflavin, iodine, calcium, phosphorus, magnesium, potassium, zinc, and iron. The summed results of observational studies of fish intake, randomized clinical tria ls of fish oil supplements, and associated mechanistic and experimental studies suggest that regular fish consumption may decrease the incidence of myocardial infarction (MI) and coronary heart disease (CHD), with more uncertain effec...
Source: JAMA Internal Medicine - March 8, 2021 Category: Internal Medicine Source Type: research

Low serum potassium levels are associated with the risk of atrial fibrillation.
CONCLUSION: We found that low serum potassium levels of less than 3.5 mmol/l are associted with increased risk of AF. PMID: 32723154 [PubMed - as supplied by publisher]
Source: Acta Cardiologica - July 30, 2020 Category: Cardiology Tags: Acta Cardiol Source Type: research

Registration of amiloride in South Africa: Cutting the Gordian knot.
Authors: Rayner BL, Spence JD, Bryer A, Mpe MT Abstract Amiloride is an antagonist of the renal tubular epithelial sodium channel (ENaC). As such, it is a diuretic that is both potassium and magnesium sparing. It is used for the treatment of potassium depletion and hypertension, and is the specific therapy for hypertension due to overactivity of the ENaC (Liddle syndrome and several additional genetic causes of the Liddle phenotype - low renin and low aldosterone). It is listed as a World Health Organization essential drug, but has never been registered in South Africa (SA) and can therefore only be prescribed unde...
Source: South African Medical Journal - October 24, 2019 Category: African Health Tags: S Afr Med J Source Type: research

Factors Influencing Quality of Life in Stroke Patients: Focus on Eating Habits
This study aimed to identify lifestyle factors about eating habits that may affect the quality of life (QOL) in elderly stroke patients. Methods: Fifty elderly patients with a first-ever stroke were enrolled. QOL was assessed by the Stroke and Aphasia QOL Scale-39-J. Lifestyle factors about eating habits were collected using questionnaires (Questions 1-17) for the intake of salt, calcium, magnesium, potassium, taurine, fiber, and protein, and the frequency of breakfast.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2019 Category: Neurology Authors: Reina Chiba, Saya Tominaga, Kasumi Mikami, Maiko Kitajima, Mayumi Urushizaka, Toshiko Tomisawa, Junko Chiba, Joji Hagii, Minoru Yasujima, Tomohiro Osanai Source Type: research

Intake of potassium- and magnesium-enriched salt improves functional outcome after stroke: a randomized, multicenter, double-blind controlled trial Vitamins, minerals, and phytochemicals
Conclusions: This study suggests that providing the DRI amount of magnesium and potassium together long term is beneficial for stroke patient recovery from neurologic deficits. This trial was registered at clinicaltrials.gov as NCT02910427.
Source: American Journal of Clinical Nutrition - November 1, 2017 Category: Nutrition Authors: Pan, W.-H., Lai, Y.-H., Yeh, W.-T., Chen, J.-R., Jeng, J.-S., Bai, C.-H., Lin, R.-T., Lee, T.-H., Chang, K.-C., Lin, H.-J., Hsiao, C.-F., Chern, C.-M., Lien, L.-M., Liu, C.-H., Chen, W.-H., Chang, A. Tags: Research Need: Role of Nutrition in Medical Management Vitamins, minerals, and phytochemicals Source Type: research

This diet advice could kill you
The American Heart Association says sodium in salt raises blood pressure. They say it increases the risk for heart disease and stroke.  But the latest science says otherwise… A British review of 34 clinical trials showed that cutting down on salt reduced blood pressure only slightly for people with hypertension.1  And a new study in The Lancet found that some low-salt diets could put you at GREATER risk of heart disease and death.2 Researchers analyzed data from 133,118 people. They wanted to see if there was a link between high sodium and heart attack, stroke and death The results were startling. People on “he...
Source: Al Sears, MD Natural Remedies - October 5, 2017 Category: Complementary Medicine Authors: Randall Hall Tags: Health Heart Health Men's Health Nutrition Women's Health Source Type: news

Intake of potassium- and magnesium-enriched salt improves functional outcome after stroke: a randomized, multicenter, double-blind controlled trial.
Conclusions: This study suggests that providing the DRI amount of magnesium and potassium together long term is beneficial for stroke patient recovery from neurologic deficits. This trial was registered at clinicaltrials.gov as NCT02910427. PMID: 28877896 [PubMed - as supplied by publisher]
Source: The American Journal of Clinical Nutrition - September 6, 2017 Category: Nutrition Authors: Pan WH, Lai YH, Yeh WT, Chen JR, Jeng JS, Bai CH, Lin RT, Lee TH, Chang KC, Lin HJ, Hsiao CF, Chern CM, Lien LM, Liu CH, Chen WH, Chang A Tags: Am J Clin Nutr Source Type: research

Urinary potassium excretion and risk of cardiovascular events Cardiovascular disease risk
Conclusion: In this cohort with oversampling of subjects with albuminuria at baseline, urinary potassium excretion was not independently associated with a lower risk of cardiovascular events.
Source: American Journal of Clinical Nutrition - May 1, 2016 Category: Nutrition Authors: Kieneker, L. M., Gansevoort, R. T., de Boer, R. A., Brouwers, F. P., Feskens, E. J., Geleijnse, J. M., Navis, G., Bakker, S. J., Joosten, M. M., for The PREVEND Study Group Tags: Cardiovascular disease risk Source Type: research

Urinary potassium excretion and risk of cardiovascular events.
CONCLUSION: In this cohort with oversampling of subjects with albuminuria at baseline, urinary potassium excretion was not independently associated with a lower risk of cardiovascular events. PMID: 26984482 [PubMed - as supplied by publisher]
Source: The American Journal of Clinical Nutrition - March 16, 2016 Category: Nutrition Authors: Kieneker LM, Gansevoort RT, de Boer RA, Brouwers FP, Feskens EJ, Geleijnse JM, Navis G, Bakker SJ, Joosten MM, PREVEND Study Group Tags: Am J Clin Nutr Source Type: research

Intakes of magnesium, potassium, and calcium and the risk of stroke among men
ConclusionsA diet rich in magnesium, potassium, and calcium may contribute to reduced risk of stroke among men. Because of significant collinearity, the independent contribution of each cation is difficult to define.
Source: International Journal of Stroke - June 4, 2015 Category: Neurology Authors: Sally N. Adebamowo, Donna Spiegelman, Alan J. Flint, Walter C. Willett, Kathryn M. Rexrode Tags: Research Source Type: research

Association between intakes of magnesium, potassium, and calcium and risk of stroke: 2 cohorts of US women and updated meta-analyses Nutritional epidemiology and public health
Conclusions: A combined mineral diet score was inversely associated with risk of stroke. High intakes of magnesium and potassium but not calcium were also significantly associated with reduced risk of stroke in women.
Source: American Journal of Clinical Nutrition - June 1, 2015 Category: Nutrition Authors: Adebamowo, S. N., Spiegelman, D., Willett, W. C., Rexrode, K. M. Tags: Nutritional Epidemiology Research Articles Nutritional epidemiology and public health Source Type: research

Association between intakes of magnesium, potassium, and calcium and risk of stroke: 2 cohorts of US women and updated meta-analyses.
CONCLUSIONS: A combined mineral diet score was inversely associated with risk of stroke. High intakes of magnesium and potassium but not calcium were also significantly associated with reduced risk of stroke in women. PMID: 25948665 [PubMed - as supplied by publisher]
Source: The American Journal of Clinical Nutrition - May 6, 2015 Category: Nutrition Authors: Adebamowo SN, Spiegelman D, Willett WC, Rexrode KM Tags: Am J Clin Nutr Source Type: research

Intakes of Potassium, Magnesium, and Calcium and Risk of Stroke Brief Reports
Conclusions— This study supports an association between high magnesium intake and a reduced stroke risk.
Source: Stroke - March 24, 2014 Category: Neurology Authors: Sluijs, I., Czernichow, S., Beulens, J. W. J., Boer, J. M. A., van der Schouw, Y. T., Verschuren, W. M. M., Grobbee, D. E. Tags: Epidemiology Brief Reports Source Type: research

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