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Nutrition: Omega 3

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Total 227 results found since Jan 2013.

Fish consumption, long-chain omega-3 fatty acids intake and risk of stroke: An updated systematic review and meta-analysis
CONCLUSIONS: Both fish consumption and LC ω3-PUFAs intake were negatively associated with the risk of stroke, especially in women, which suggest that increased intake of fishery products and LC ω3-PUFAs may benefit primary prevention of stroke.PMID:33787050 | DOI:10.6133/apjcn.202103_30(1).0017
Source: Asia Pacific Journal of Clinical Nutrition - March 31, 2021 Category: Nutrition Authors: Chen Chen Hui Huang Qiu-Qin Dai Jing Ren Hong-Hua Cai Wen-Jia Hu Xiu-Juan Zhang Wang-Tao Zhong Xiang-Yong Li Source Type: research

The Nutraceutical Potential of Omega-3 Alpha-Linolenic Acid in Reducing the Consequences of Stroke.
Abstract Stroke is a worldwide major cause of mortality and morbidity. Preclinical studies have identified over 1000 molecules with brain-protective properties. More than 200 clinical trials have evaluated neuroprotective candidates for ischemic stroke yet, to date almost all failed, leading to a re-analysis of treatment strategies against stroke. An emerging view is to seek combinatory therapy, or discovering molecules able to stimulate multiple protective and regenerative mechanisms. A pertinent experimental approach to identify such candidates is the study of brain preconditioning, which refers to how the brain...
Source: Biochimie - June 16, 2015 Category: Biochemistry Authors: Blondeau N Tags: Biochimie Source Type: research

Associations of dietary polychlorinated biphenyls and long-chain omega-3 fatty acids with stroke risk.
CONCLUSION: Dietary PCB exposure was associated with an increased risk of hemorrhagic stroke, whereas a protective association was observed for dietary EPA-DHA intake. PMID: 27473885 [PubMed - as supplied by publisher]
Source: Environment International - July 25, 2016 Category: Environmental Health Authors: Kippler M, Larsson SC, Berglund M, Glynn A, Wolk A, Åkesson A Tags: Environ Int Source Type: research

Intravenous Treatment with a Long-Chain Omega-3 Lipid Emulsion Provides Neuroprotection in a Murine Model of Ischemic Stroke – A Pilot Study
by Dirk Berressem, Konrad Koch, Nicole Franke, Jochen Klein, Gunter P. Eckert Single long-chain omega-3 fatty acids (e.g. docosahexaenoic acid (DHA) or eicosapentaenoic acid (EPA)) are known for their neuroprotective properties associated with ischemic stroke. This pilot study aimed to test the effectiveness of an acute treatment with a long-chain omega-3 lipid emulsion (Om egaven 10%®, OGV) that contains fish oil (DHA 18 mg/ml; EPA 21 mg/ml) and α-tocopherol (0.2 mg/ml) in a transient middle cerebral artery occlusion (MCAO) model of ischemic stroke in mice. For this purpose, female CD-1 mice were anesthetized and subje...
Source: PLoS One - November 29, 2016 Category: Biomedical Science Authors: Dirk Berressem Source Type: research

Transgenic Overproduction of Omega-3 Polyunsaturated Fatty Acids Provides Neuroprotection and Enhances Endogenous Neurogenesis after Stroke.
Abstract Strokes are devastating as there are no current therapies to prevent the long term neurological deficits that they cause. Soon after ischemic stroke, there is proliferation and differentiation of neural stem/progenitor cells as an important mechanism for neuronal restoration. However, endogenous neurogenesis by itself is insufficient for effective brain repair after stroke as most newborn neurons do not survive. One fascinating strategy for stroke treatment would thus be maintaining the survival and/or promoting the differentiation of endogenous neural stem/progenitor cells. Using transgenic (Tg) mice ove...
Source: Current Molecular Medicine - August 22, 2013 Category: Molecular Biology Authors: Hu X, Zhang F, Leak RK, Zhang W, Iwai M, Stetler RA, Dai Y, Zhao A, Gao Y, Chen J Tags: Curr Mol Med Source Type: research