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Total 2719 results found since Jan 2013.

The endogenous and exogenous brain-derived neurotrophic factor plays pivotal roles in the pathogenesis of stroke onset in high salt-loaded hypertensive rats
Exp Gerontol. 2021 Feb 17;147:111286. doi: 10.1016/j.exger.2021.111286. Online ahead of print.ABSTRACTBrain-derived neurotrophic factor (BDNF) is known to have neuroprotective effects on multiple neurovascular diseases especially poststroke recovery. On the other hand, BDNF reported to increase blood pressure (BP) which is one of the major risk factors for stroke onset. To clarify the conflicting effects on stroke onset, we examined the expression of endogenous BDNF in relation to stroke onset. In addition, we explored the effect of exogenous central BDNF against stroke onset and all-cause mortality as the primary endpoint...
Source: Experimental Gerontology - February 20, 2021 Category: Geriatrics Authors: Yu Hasegawa Yushin Takemoto Kenyu Hayashi Koki Kameno Shokei Kim-Mitsuyama Source Type: research

Habitual flavonoid intake and ischemic stroke incidence in the Danish Diet, Cancer, and Health Cohort
CONCLUSIONS: These findings suggest that moderate habitual consumption of healthy flavonoid-rich foods is associated with a lower risk of ischemic stroke and further investigation is therefore warranted.PMID:33963737 | DOI:10.1093/ajcn/nqab138
Source: The American Journal of Clinical Nutrition - May 8, 2021 Category: Nutrition Authors: Benjamin H Parmenter Frederik Dalgaard Kevin Murray Aedin Cassidy Catherine P Bondonno Joshua R Lewis Kevin D Croft Cecilie Kyr ø Gunnar Gislason Augustin Scalbert Anne Tj ønneland Jonathan M Hodgson Nicola P Bondonno Source Type: research

Stroke risk prediction using machine learning: a prospective cohort study of 0.5 million Chinese adults
ConclusionAmong several approaches, an ensemble model combining both GBT and Cox models achieved the best performance for identifying individuals at high risk of stroke in a contemporary study of Chinese adults. The results highlight the potential value of expanding the use of ML in clinical practice.
Source: Journal of the American Medical Informatics Association - May 9, 2021 Category: Information Technology Source Type: research

Habitual flavonoid intake and ischemic stroke incidence in the Danish Diet, Cancer, and Health Cohort
CONCLUSIONS: These findings suggest that moderate habitual consumption of healthy flavonoid-rich foods is associated with a lower risk of ischemic stroke and further investigation is therefore warranted.PMID:33963737 | DOI:10.1093/ajcn/nqab138
Source: The American Journal of Clinical Nutrition - May 8, 2021 Category: Nutrition Authors: Benjamin H Parmenter Frederik Dalgaard Kevin Murray Aedin Cassidy Catherine P Bondonno Joshua R Lewis Kevin D Croft Cecilie Kyr ø Gunnar Gislason Augustin Scalbert Anne Tj ønneland Jonathan M Hodgson Nicola P Bondonno Source Type: research

Role of Renal Dysfunction as a Prognostic Factor in Acute Stroke Patients at a Tertiary Hospital in Northeastern Nigeria
Saudi J Kidney Dis Transpl. 2021 Jan-Feb;32(1):199-203. doi: 10.4103/1319-2442.318524.ABSTRACTChronic kidney disease (CKD) and stroke share many common risk factors, and the presence of CKD confers added risk factors for stroke. With increasing interest and understanding of the close relationship between the kidney and the brain, this study aims to assess the prevalence and impact of renal dysfunction on outcomes acute stroke patients. This is a prospective hospital-based study carried out in the neurology unit of University of Maiduguri Teaching Hospital, Maiduguri, northeastern Nigeria. The study population consisted of ...
Source: Saudi Journal of Kidney Diseases and Transplantation - June 19, 2021 Category: Urology & Nephrology Authors: Mohammad Maina Sulaiman Musa Mamman Watila Jummai Shettima Ibrahim Ummate Yakubu Wilberforce Nyandaiti Source Type: research