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Total 615 results found since Jan 2013.
O27 Frailty and co-morbidity in people with osteoarthritis and rheumatoid arthritis
Conclusion Co-morbidity is associated with an increased occurrence of pre-frailty and frailty among people with OA and RA and interacts synergistically with OA and RA to increase the likelihood of pre-frailty and frailty.Disclosure M.J. Cook: None.M. Lunt: None.S.M.M. Verstappen: None.T.W. O'Neill: None.
Source: Rheumatology - April 26, 2021 Category: Rheumatology Source Type: research
P030 Antiphospholipid syndrome and giant cell arteritis: a coincidence or connection?
Conclusion In summary, this is a case of GCA and APS, treated with prednisolone, aspirin, warfarin and tocilizumab. There is increasing evidence describing the presence of antiphospholipid antibodies in patients with vasculitis. However, the role of these antibodies in GCA and the clinical significance rema ins unclear. This case reports highlights the need for physicians to consider APS in patients who have a history of GCA and subsequently develop arterial or venous embolic events.Disclosure L. Sammut: None.E. Htut: None.
Source: Rheumatology - April 26, 2021 Category: Rheumatology Source Type: research
Role Of Glp-1 Analogs In The Management Of Diabetes And Its Secondary Complication
Mini Rev Med Chem. 2021 Apr 21. doi: 10.2174/1389557521666210422114909. Online ahead of print.ABSTRACTThe cardiovascular complications of type 2 diabetes mellitus (T2DM) include myocardial infarction, heart failure, peripheral vascular disease and, stroke and retinopathy, nephropathy and neuropathy are microvascular complications. While the newer therapies like glitazones or even dipeptidyl-peptidase-IV (DPP-IV) inhibitors increase the risk of therapy, the Glucagon Like Peptide-1 Receptor Agonists (GLP-1RAs), were reported as suitable alternates. The GLP-1RAs reduce the major adverse cardiovascular events (MACE), have anti...
Source: Mini Reviews in Medicinal Chemistry - April 23, 2021 Category: Chemistry Authors: Ponnurengam Malliappan Sivakumar B Premkumar Prabhawathi Veluchamy Pranav Kumar Prabhakar Source Type: research
Supervised Obesity Reduction Trial for AF ablation patients: results from the SORT-AF trial
ConclusionThe SORT-AF study shows that AF ablation is safe and successful in obese patients using continuous monitoring via ILR. Although the primary endpoint of AF burden after ablation did not differ between the two groups, the effects of weight loss and improvement of exercise activity were beneficial for obese patients with persistent AF demonstrating the relevance of life-style management as an important adjunct to AF ablation in this setting.Trial registration numberNCT02064114.
Source: Europace - April 22, 2021 Category: Cardiology Source Type: research
Baseline Risk of Metabolic Syndrome Among Participants Post Stroke Enrolled in an Intensive Lifestyle Intervention to Promote Weight-Loss
To describe the (1) weight and medical history and (2) physical activity and eating behaviors of participants post stroke enrolled in a 12-month intensive lifestyle intervention.
Source: Archives of Physical Medicine and Rehabilitation - March 31, 2021 Category: Rehabilitation Authors: Simon Driver, Chad Swank, Katherine Froehlich-Grobe, Evan Elizabeth McShan, Stephanie Calhoun, Sharon Brown, Noelia Ramirez, Monica Bennett, Librada Callender, Danielle Miro, Rosemary Dubiel, Sridevi Mukkamala Tags: Late Breaking Research Papers Posters Source Type: research
BMI and BMI change following incident type 2 diabetes and risk of microvascular and macrovascular complications: the EPIC-Potsdam study
Conclusions/interpretationAmong people with incident type 2 diabetes, pre-diagnosis BMI was positively associated with microvascular complications, while a reduced risk was observed with weight loss when compared with stable weight. The relationships with macrovascular disease were less clear.Graphical abstract
Source: Diabetologia - March 8, 2021 Category: Endocrinology Source Type: research
Potential impact of gradual reduction of fat content in manufactured and out-of-home food on obesity in the United Kingdom: a modeling study
CONCLUSIONS: A modest fat reduction (particularly in SFA) in widely consumed foods would prevent obesity, type 2 diabetes, and cardiovascular disease.PMID:33677474 | DOI:10.1093/ajcn/nqaa396
Source: The American Journal of Clinical Nutrition - March 7, 2021 Category: Nutrition Authors: Roberta Alessandrini Feng J He Yuan Ma Vincenzo Scrutinio David S Wald Graham A MacGregor Source Type: research
