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Establishment and validation of a prediction model for ischemic stroke risks in patients with type 2 diabetes
Diabetes is a formidable global health threat because of its high prevalence and numerous complications. Furthermore, diabetes is a leading cause of mortality and microvascular and macrovascular diseases, including coronary diseases, cerebrovascular diseases, and peripheral vascular diseases. A recent study reports that risk of stroke in patients with type 2 diabetes is two to five times higher than the general population[1]. The World Health Organization MONICA project reported that stroke incidence is higher among ethnic Chinese population than among Western population [2].
Source: Diabetes Research and Clinical Practice - February 17, 2018 Category: Endocrinology Authors: Tsai-Chung Li, Hsiang-Chi Wang, Chia-Ing Li, Chiu-Shong Liu, Wen-Yuan Lin, Chih-Hsueh Lin, Sing-Yu Yang, Cheng-Chieh Lin Source Type: research

Evaluating the impact of type 2 diabetes mellitus on cardiovascular risk in persons with metabolic syndrome using the UKPDS risk engine.
CONCLUSION: MS was more common in subjects with T2DM compared with controls (irrespective of the diagnostic criteria used) and MS appears to increase the risk of a coronary event in subjects with T2DM by threefold. Also from this study, MS did not appear to cause an additional increase in the risk of stroke in subjects with T2DM. PMID: 26396537 [PubMed]
Source: Diabetes Metab - September 26, 2015 Category: Endocrinology Authors: Ogedengbe OS, Ezeani IU, Chukwuonye II, Anyabolu EN, Ozor II, Eregie A Tags: Diabetes Metab Syndr Obes Source Type: research

Evaluating the impact of type 2 diabetes mellitus on cardiovascular risk in persons with metabolic syndrome using the UKPDS risk engine
Conclusion: MS was more common in subjects with T2DM compared with controls (irrespective of the diagnostic criteria used) and MS appears to increase the risk of a coronary event in subjects with T2DM by threefold. Also from this study, MS did not appear to cause an additional increase in the risk of stroke in subjects with T2DM.Keywords: diabetes mellitus, metabolic syndrome, coronary heart disease, cardiovascular disease, UKPDS risk engine
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - September 15, 2015 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research

Cardiovascular Programming During and After Diabetic Pregnancy: Role of Placental Dysfunction and IUGR
This study demonstrated that the incidence of ischemic heart disease and death were three times higher among men with low birth weight compared to men with high birth weight (5). Epidemiological investigations of adults born at the time of the Dutch famine between 1944 and 1945 revealed an association between maternal starvation and a low infant birth weight with a high incidence of hypertension and coronary heart disease in these adults (23). Furthermore, Painter et al. reported the incidence of early onset coronary heart disease among persons conceived during the Dutch famine (24). In that regard, Barker's findin...
Source: Frontiers in Endocrinology - April 8, 2019 Category: Endocrinology Source Type: research

Obesity: single house for many evils.
Authors: Kumar A, Nayak BP, Kumar A Abstract World Health Organization (WHO) considers obesity as one of the fastest growing metabolic disorders other than diabetes. It is a complex interplay of lifestyle and associated genes. Obesity has been considered as a disease with multiple targets and very often compared in this sense with its sibling disease type 2 diabetes. The disease is pathology of the adipocytes and develops as a result of hypertrophy and hyperplasia of these cells, former being the major concern but its effects could be seen on various organs in the form of cardio-vascular disease, stroke, cancer, di...
Source: Minerva Endocrinologica - June 4, 2015 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research

Get Moving: High Physical-Activity Level Reduces Risk of 5 Diseases Get Moving: High Physical-Activity Level Reduces Risk of 5 Diseases
The greatest risk reduction for diabetes, cancers, heart disease, and stroke is seen at higher activity levels than those recommended by the World Health Organization.Medscape Medical News
Source: Medscape Diabetes Headlines - August 10, 2016 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

Obesity: single house for many evils.
Authors: Kumar A, Nayak BP, Kumar A Abstract World Health Organization (WHO) considers obesity as one of the fastest growing metabolic disorders other than diabetes. It is a complex interplay of lifestyle and associated genes. Obesity has been considered as a disease with multiple targets and very often compared in this sense with its sibling disease type 2 diabetes. The disease is pathology of the adipocytes and develops as a result of hypertrophy and hyperplasia of these cells, former being the major concern but its effects could be seen on various organs in the form of cardio-vascular disease, stroke, cancer, di...
Source: Minerva Endocrinologica - September 9, 2016 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research