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Platelets, Macrophages, and Thromboinflammation in Chagas Disease
J Inflamm Res. 2022 Oct 4;15:5689-5706. doi: 10.2147/JIR.S380896. eCollection 2022.ABSTRACTChagas disease (CD) is a major health problem in the Americas and an emerging health problem in Europe and other nonendemic countries. Several studies have documented persistence of the protozoan parasite Trypanosoma cruzi, and oxidative and inflammatory stress are major pathogenic factor. Mural and cardiac thrombi, cardiac arrhythmias, and cardiomyopathy are major clinical features of CD. During T. cruzi infection, parasite-released factors induce endothelial dysfunction along with platelet (PLT) and immune-cell activation. PLTs hav...
Source: Cell Research - October 11, 2022 Category: Cytology Authors: Subhadip Choudhuri Nisha J Garg Source Type: research

Association between occupations and selected noncommunicable diseases: A matched case-control among Thai informal workers
CONCLUSIONS: There is a need to understand what are the key factors that increase the risk for NCDs among informal sector workers. Health promotion campaigns are needed to raise awareness among economically and social disadvantaged informal workers about the risk for NCDs. This will require collaboration between public health and the workforce, and allocation of government budgets to address the needs of these workers.PMID:34263504 | PMC:PMC8279900 | DOI:10.1002/1348-9585.12249
Source: Journal of Occupational Health - July 15, 2021 Category: Occupational Health Authors: Mathuros Tipayamongkholgul Pornpimol Kongtip Susan Woskie Source Type: research

AHA News: Should You Be Worried About Blood-Hungry ' Kissing Bugs ' ?
FRIDAY, May 3, 2019 (American Heart Association News) -- It sounds like something out of a horror film: A blood-hungry insect feeds on its prey ' s faces while they sleep, leaving behind a parasite that can cause stroke and heart disease. But the...
Source: Drugs.com - Daily MedNews - May 3, 2019 Category: General Medicine Source Type: news

Superbugs, Anti-Vaxxers Make WHO ’ s List Of 10 Global Health Threats
(CNN) — From climate change to superbugs, the World Health Organization has laid out 10 big threats to our global health in 2019. And unless these threats get addressed, millions of lives will be in jeopardy. Here’s a snapshot of 10 urgent health issues, according to the United Nations’ public health agency: Not vaccinating when you can One of the most controversial recent health topics in the US is now an international concern. “Vaccine hesitancy — the reluctance or refusal to vaccinate despite the availability of vaccines — threatens to reverse progress made in tackling vaccine-prevent...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 21, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Local TV Source Type: news

Environmental Pollution: An Under-recognized Threat to Children’s Health, Especially in Low- and Middle-Income Countries
Conclusions Patterns of disease are changing rapidly in LMICs. Pollution-related chronic diseases are becoming more common. This shift presents a particular problem for children, who are proportionately more heavily exposed than are adults to environmental pollutants and for whom these exposures are especially dangerous. Better quantification of environmental exposures and stepped-up efforts to understand how to prevent exposures that cause disease are needed in LMICs and around the globe. To confront the global problem of disease caused by pollution, improved programs of public health monitoring and environmental protecti...
Source: EHP Research - March 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Brief Communication March 2016 Source Type: research

High-salt diet could protect against invading microbes
Most people consume more salt than they need and therefore have a higher risk of heart disease and stroke, which are the two leading causes of death worldwide. But a new study reveals that dietary salt could have a biological advantage: Defending the body against invading microbes. A high-salt diet increased sodium accumulation in the skin of mice, thereby boosting their immune response to a skin-infecting parasite.
Source: ScienceDaily Headlines - March 3, 2015 Category: Science Source Type: news

Cardiology leaders call for global prevention of heart disease, stroke
Heart disease and stroke contribute to 30 percent of global deaths, more than all infectious and parasitic diseases combined, and 11 cardiovascular organizations are calling for the United Nations to address prevention of heart disease and other non-communicable diseases.
Source: ScienceDaily Headlines - September 26, 2014 Category: Science Source Type: news