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Prognostic implications of the 4S-AF scheme to characterize new-onset atrial fibrillation after myocardial infarction
CONCLUSIONS: Characterization of NOAF using the 4S-AF scheme aids in the risk stratification of AMI patients with NOAF.PMID:37037721 | DOI:10.1016/j.ejim.2023.04.003
Source: European Journal of Internal Medicine - April 10, 2023 Category: Internal Medicine Authors: Jiachen Luo Zhiqiang Li Xiaoming Qin Xingxu Zhang Xiangdong Liu Wenming Zhang Wei Xu Yiwei Zhang Yuan Fang Baoxin Liu Yidong Wei NOAFCAMI-SH Registry Investigators Source Type: research

Association between human immunodeficiency virus serostatus and the prevalence of atrial fibrillation
Atrial fibrillation (AF) leads to increased risk for stroke. Human immunodeficiency virus (HIV) is associated with cardiovascular disease (CVD), although it is unclear if HIV is associated with AF. The purpose of this study was to evaluate the association between HIV serostatus and the prevalence of AF in the Multicenter AIDS Cohort Study. A cross sectional study was conducted among 1674 HIV-infected (HIV+) and uninfected (HIV–) men who completed resting 12-lead electrocardiograms, and/or ambulatory electrocardiogram monitoring. Multivariable logistic regression was used to evaluate the association between AF, defined...
Source: Medicine - July 23, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Low to moderate quality evidence demonstrates the potential benefits and adverse events of cannabinoids for certain medical indications
Commentary on: Whiting PF, Wolff RF, Deshpande S, et al.. Cannabinoids for medical use: a systematic review and meta-analysis. JAMA 2015;313:2456–73. Context As of September 2015, 23 states and the District of Columbia in the USA legalised the medicinal use of marijuana, underscoring the need for physicians to understand the science underlying medical marijuana as well as the practical issues associated with it. For years policymakers, scientists and physicians alike have debated the potential risks associated with marijuana use.1 Now marijuana's utility as a treatment for certain medical indications has taken focus....
Source: Evidence-Based Medicine - January 22, 2016 Category: Internal Medicine Authors: Hill, K. P., Hurley-Welljams-Dorof, W. M. Tags: Sexual transmitted infections (viral), Clinical trials (epidemiology), General practice / family medicine, Genetics, Immunology (including allergy), HIV/AIDS, Drugs: CNS (not psychiatric), Pain (neurology), Sleep disorders (neurology), Stroke, Ophthalmolo Source Type: research

The Role of Decision Aids in Depression Care
Clarion calls about enhancing detection and management of depression in primary care have reiterated several truisms: Depression is as prevalent as many common medical disorders, treatable yet frequently undertreated, responsible for enormous occupational and social impairment as well as adverse effects on the costs, treatment outcomes, and mortality of comorbid medical diseases. Depression is second only to low back pain in years lived with disability (YLD), a metric that incorporates disease prevalence, age of onset, chronicity, and impairment. The YLDs attributable to depression exceed those accounted for by diabetes, i...
Source: JAMA Internal Medicine - September 28, 2015 Category: Internal Medicine Source Type: research

Assessment of upper extremity function in multiple sclerosis: review and opinion.
Authors: Kraft GH, Amtmann D, Susan E B, Finlayson M, Sutliff MH, Tullman M, Sidovar M, Rabinowicz AL Abstract Upper extremity (UE) dysfunction may be present in up to ~80% of individuals with multiple sclerosis (MS), although its importance may be under-recognized relative to walking impairment, which is the hallmark symptom of MS. Upper extremity dysfunction affects independence and can impact the ability to use walking aids. Under-recognition of UE dysfunction may result in part from limited availability of performance-based and patient self-report measures that are validated for use in MS and that can be readil...
Source: Postgraduate Medicine - November 28, 2014 Category: Internal Medicine Tags: Postgrad Med Source Type: research

Sudden cardiac death: a critical appraisal of the implantable cardioverter defibrillator
Summary ImportanceApproximately 350,000 Americans still die of sudden cardiac death each year. This exceeds the number of patients who die annually from stroke, lung cancer, breast cancer and AIDS combined. ObjectiveThis review aims to trace the history of implantable cardioverter defibrillators (ICD) with reference to landmark trials and their influence on the formulation of Medicare guidelines for ICD implantation criteria. This paper will also discuss the cost‐effectiveness of ICDs and the quality of life after implantation. The reasons for the disparity between guidelines for implantation and actual clinical practice...
Source: International Journal of Clinical Practice - December 22, 2013 Category: Internal Medicine Authors: A. Rajabali, E. K. Heist Tags: Review Article Source Type: research

Neurological complications of HIV
Abstract: The HIV virus is both neurotropic and immunotropic, causing progressive destruction of both systems. Although their frequency has been markedly reduced in the combination antiretroviral therapy (cART) era, neurological presentations and complications of HIV remain common. Neurological opportunistic infections (OI) and diseases occur in advanced HIV disease and include cryptococcal meningitis, progressive multifocal encephalopathy, primary cerebral lymphoma and cerebral toxoplasmosis. Neurological disease directly associated with HIV may occur at any stage in the progress of HIV disease, from the aseptic meningiti...
Source: Medicine - August 1, 2013 Category: Internal Medicine Authors: Adam Croucher, Alan Winston Tags: HIV/AIDS by system Source Type: research