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Cerebrovascular disease in patients with COVID-19: neuroimaging, histological and clinical description
We describe pathological and radiological data consistent with thrombotic microangiopathy caused by endotheliopathy with a haemorrhagic predisposition.
Source: Brain - July 9, 2020 Category: Neurology Source Type: research

Universal laboratory testing for SARS-CoV-2 in hyperacute stroke during the COVID-19 pandemic
The coronavirus disease 2019 (COVID-19) pandemic necessitates organizational and structural adjustments to local health care systems to protect medical professionals and patients from infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (1). Particularly older individuals and those with cardiovascular comorbidities are thought to be at increased risk of COVID-19 (2). Consequently, stroke patients can be considered an at-risk population and might benefit from infection control screens at hospital entry (3,4).
Source: Journal of Stroke and Cerebrovascular Diseases - June 19, 2020 Category: Neurology Authors: Kristian Barlinn, Timo Siepmann, Lars-Peder Pallesen, Simon Winzer, Annahita Sedghi, Percy Schroettner, Kristina Hochauf-Stange, Alexandra Prakapenia, Haidar Moustafa, Katja de With, Jennifer Linn, Heinz Reichmann, Jessica Barlinn, Volker Puetz Tags: Original Article Source Type: research

Doctors Are Worried About the Unprecedented Drop in Emergency Room Visits During the COVID-19 Pandemic
In late May, an otherwise relatively healthy New York City woman began having trouble speaking, and she felt weak on the right side of her body. But she could still walk and take care of herself, and with the coronavirus pandemic raging, visiting a hospital seemed too dangerous. The next day, her speech had gotten worse, and she could barely move the right side of her body. Her family called 911 and she was rushed to the hospital, where doctors determined she had suffered a stroke. By the time the woman left the hospital, she was no longer able to walk by herself, and was having difficulty speaking and understanding other...
Source: TIME: Health - June 4, 2020 Category: Consumer Health News Authors: Alejandro de la Garza Tags: Uncategorized COVID-19 Source Type: news

COVID-19: Stroke Admissions, Emergency Department Visits, and Prevention Clinic Referrals.
Abstract We assessed the impact of the coronavirus disease 19 (COVID-19) pandemic on code stroke activations in the ED, stroke unit admissions, and referrals to the stroke prevention clinic at London's regional stroke center, serving a population of 1.8 million in Ontario, Canada. We found a 20% drop in the number of code strokes in 2020 compared to 2019, immediately after the first cases of COVID-19 were officially confirmed. There were no changes in the number of stroke admissions and there was a 22% decrease in the number of clinic referrals, only after the provincial lockdown. Our findings suggest that the dec...
Source: The Canadian Journal of Neurological Sciences - May 25, 2020 Category: Neurology Authors: Bres Bullrich M, Fridman S, Mandzia JL, Mai LM, Khaw A, Vargas Gonzalez JC, Bagur R, Sposato LA Tags: Can J Neurol Sci Source Type: research

Unprotected stroke management in an undiagnosed case of Severe Acute Respiratory Syndrome Coronavirus 2 infection
We report the case of a 79-year-old woman, who was admitted for a wake-up stroke due to occlusion of the left middle cerebral artery. She was treated outside the COVID-19-dedicated track of the hospital because she had no concomitant signs or symptoms suggestive of SARS-CoV-2 infection nor recent contact with other infected individuals.
Source: Journal of Stroke and Cerebrovascular Diseases - May 22, 2020 Category: Neurology Authors: Claudia Papi, Gregorio Spagni, Andrea Alexandre, Paolo Calabresi, Giacomo Della Marca, Aldobrando Broccolini Source Type: research

Unusual Symptoms of Coronavirus: What We Know So Far
While most people are familiar with the hallmark symptoms of COVID-19 by now—cough, fever, muscle aches, headaches and difficulty breathing—a new crop of medical conditions are emerging from the more than 4 million confirmed cases of the disease around the world. These include skin rashes, diarrhea, kidney abnormalities and potentially life-threatening blood clots. It’s not unusual for viruses to directly infect and affect different tissues and organs in the body, but it is a bit unusual for a primarily respiratory virus like SARS-CoV-2, which is responsible for COVID-19, to have such a wide-ranging reach...
Source: TIME: Health - May 19, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news

COVID-19: A Personalized Cardiometabolic Approach for Reducing Complications and Costs. The Role of Aging Beyond Topics
AbstractCOVID 19 is much more than an infectious disease by SARS-CoV-2 followed by a disproportionate immune response. An older age, diabetes and history of cardiovascular disease, especially hypertension, but also chronic heart failure and coronary artery disease among others, are between the most important risk factors. In addition, during the hospitalization both hyperglycaemia and heart failure are frequent. Less frequent are acute coronary syndrome, arrhythmias and stroke. Accordingly, not all prolonged stays or even deaths are due directly to SARS-CoV-2. To our knowledge, this is the first review, focusing both on ca...
Source: The Journal of Nutrition, Health and Aging - May 11, 2020 Category: Nutrition Source Type: research

Tubuloreticular inclusions in COVID-19-related collapsing glomerulopathy
A 79-year-old male of African ancestry, with a history of hemorrhagic stroke, monoclonal gammopathy of unknown significance and chronic kidney disease stage 3 due to hypertension was admitted to Bichat hospital on day 1 after the first symptom of COVID-19 (fever). SARS-CoV 2 PCR was positive on nasal swab. At admission urinary dipstick was normal and plasma creatinine was 224 μmol/L. On day 4 plasma albumin was at 29 g/L and proteinuria was 11.4 g per gram of urinary creatinine (80% of albumin).
Source: Kidney International - April 26, 2020 Category: Urology & Nephrology Authors: Fran çois Gaillard, Sophie Ismael, Aurélie Sannier, Hassan Tarhini, Thomas Volpe, Clarisse Greze, Marie Christine Verpont, Ilyass Zouhry, Christophe Rioux, François-Xavier Lescure, David Buob, Eric Daugas Tags: nephrology image Source Type: research

Tubuloreticular inclusions in COVID-19 –related collapsing glomerulopathy
A 79-year-old man of African ancestry, with a history of hemorrhagic stroke, monoclonal gammopathy of unknown significance, and stage 3 chronic kidney disease due to hypertension, was admitted to Bichat Hospital on day 1 after the first symptom of COVID-19 (fever). Severe acute respiratory syndrome coronavirus 2 polymerase chain reaction was positive on nasal swab. At admission, urinary dipstick was normal and plasma creatinine was 224 μmol/l. On day 4 plasma albumin was at 29 g/l and proteinuria was 11.4 g per gram of urinary creatinine (80% of albumin).
Source: Kidney International - April 26, 2020 Category: Urology & Nephrology Authors: Fran çois Gaillard, Sophie Ismael, Aurélie Sannier, Hassan Tarhini, Thomas Volpe, Clarisse Greze, Marie Christine Verpont, Ilyass Zouhry, Christophe Rioux, François-Xavier Lescure, David Buob, Eric Daugas Tags: Nephrology Image Source Type: research

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