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Potential association between bacterial infections and ischemic stroke based on fifty case-control studies: A systematic review and meta-analysis
CONCLUSIONS: In this meta-analysis, a significant relationship was observed between infection by three bacteria such as C. pneumoniae, H. pylori, and M. tuberculosis with the occurrence of ischemic stroke. Furthermore, due to the similarity between TLRVYK domain in β2-glycoprotein-I and TLRVYK peptide in various of microorganisms, produced antibodies against pathogens interact with β2-glycoprotein-I, hence the cross-reaction phenomenon increases the positive relationship between infectious diseases and ischemic stroke.PMID:35592534 | PMC:PMC9112101 | DOI:10.1016/j.nmni.2022.100980
Source: Atherosclerosis - May 20, 2022 Category: Cardiology Authors: M Keikha M Karbalaei Source Type: research

Carotid intima media thickness and blood biomarkers of atherosclerosis in patients after stroke or myocardial infarction.
CONCLUSIONS: Our study supports linear correlations between CIMT and IC and hs-CRP levels. However, these associations seem to depend on the type of vascular burden. PMID: 28051279 [PubMed - in process]
Source: Croatian Medical Journal - December 30, 2016 Category: Journals (General) Authors: Kurkowska-Jastrzebska I, Karlinski MA, Błazejewska-Hyzorek B, Sarzynska-Dlugosz I, Filipiak KJ, Czlonkowska A Tags: Croat Med J Source Type: research

Infectious burden and cognitive function: The Northern Manhattan Study
Conclusion: A measure of IB associated with stroke risk and atherosclerosis was independently associated with cognitive performance in this multiethnic cohort. Past infections may contribute to cognitive impairment.
Source: Neurology - March 25, 2013 Category: Neurology Authors: Katan, M., Moon, Y. P., Paik, M. C., Sacco, R. L., Wright, C. B., Elkind, M. S. V. Tags: All Infections, All Cerebrovascular disease/Stroke, All Cognitive Disorders/Dementia ARTICLE Source Type: research

Intracranial Large Artery Stenosis and Past Infectious Exposures: Results From the NOMAS Cohort
CONCLUSIONS: Chronic infectious exposures, specifically herpes simplex virus 2 and cytomegalovirus were associated with asymptomatic ILAS as seen on magnetic resonance angiogram imaging. This may represent an additional target of intervention in the ongoing effort to stem the substantial global burden of strokes related to ILAS.PMID:35105181 | DOI:10.1161/STROKEAHA.121.036793
Source: Herpes - February 2, 2022 Category: Infectious Diseases Authors: Amol Mehta Farid Khasiyev Clinton B Wright Tatjana Rundek Ralph L Sacco Mitchell S V Elkind Jose Gutierrez Source Type: research

Infectious Burden and Cognitive Decline in the Northern Manhattan Study
ConclusionA quantitative stroke risk‐weighted measure of IB explained variability in baseline executive function performance and associated with decline in memory. Past exposure to common infections may contribute to vascular cognitive impairment and warrants further study.
Source: Journal of the American Geriatrics Society - August 20, 2015 Category: Geriatrics Authors: Clinton B. Wright, Hannah Gardener, Chuanhui Dong, Mitsuhiro Yoshita, Charles DeCarli, Ralph L. Sacco, Yaakov Stern, Mitchell S. V. Elkind Tags: Clinical Investigations Source Type: research

Infection and atherosclerosis: TLR-dependent pathways.
This article reviews the role of TLRs in the process of atherosclerosis after C. pneumoniae and other infections and the current status of treatment, with a view to providing a new direction and potential therapeutic targets for the study of ASVD. PMID: 32002588 [PubMed - as supplied by publisher]
Source: Cellular and Molecular Life Sciences : CMLS - January 29, 2020 Category: Cytology Authors: Li B, Xia Y, Hu B Tags: Cell Mol Life Sci Source Type: research