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Source: Frontiers in Neurology
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Total 2557 results found since Jan 2013.
Association between baseline pulse pressure and hospital mortality in non-traumatic subarachnoid hemorrhage patients: a retrospective cohort study
ConclusionFor patients with non-traumatic SAH, the association between baseline PP and risk of hospital mortality was non-linear, with an inflection point at 60 mmHg and a minimal risk at 57 to 68 mmHg (Q2) of baseline PP level.
Source: Frontiers in Neurology - July 17, 2023 Category: Neurology Source Type: research
Effect of weekend versus weekday admission on the mortality of acute ischemic stroke patients in China: an analysis of data from the Chinese acute ischemic stroke treatment outcome registry
ConclusionThe weekend effect was not observed in the mortality of patients with AIS regardless of rural–urban status or geographic region in China.
Source: Frontiers in Neurology - July 17, 2023 Category: Neurology Source Type: research
Associations of lipids and lipid-lowering drugs with risk of stroke: a Mendelian randomization study
ConclusionWe cautiously find that LDL-C and apoB was positively correlated with LAS. These findings suggest that the reducing LDL-C levels could be an effective prevention strategy for reducing the risk of stroke.
Source: Frontiers in Neurology - July 17, 2023 Category: Neurology Source Type: research
The use of alteplase, although safe, does not offer clear clinical advantages when mild stroke is non-disabling
This study aimed to investigate the efficacy and safety of alteplase in patients with mild, non-disabling AIS.MethodsWe included all consecutive patients admitted for AIS at our institution from January 2015 to May 2022 who presented a baseline NIHSS score of 0–5 and fit the criteria to receive intravenous thrombolysis. In order to select only subjects with non-disabling AIS, we excluded patients who scored more than 1 point in the following NIHSS single items: vision, language, neglect, and single limb. Patients who scored at least 1 point in the NIHSS consciousness item were excluded as well. This study is a retrospect...
Source: Frontiers in Neurology - July 17, 2023 Category: Neurology Source Type: research
Association between superior longitudinal fasciculus, motor recovery, and motor outcome after stroke: a cohort study
ConclusionBoth SLF I and SLF II appeared to participate in poststroke motor recovery of complex movements but not in the motor outcome. These results argue that visually/spatially oriented motor tasks as well as more complex motor tasks using parietal associative areas should be used for poststroke rehabilitation strategies.
Source: Frontiers in Neurology - July 14, 2023 Category: Neurology Source Type: research
Serum cold-inducible RNA-binding protein (CIRP) levels as a prognostic indicator in patients with acute ischemic stroke
ConclusionThe findings of this study suggest an elevation in serum CIRP levels among patients with AIS. These levels are positively correlated with the severity of AIS and serve as indicators of a poor prognosis. Therefore, CIRP could serve as a target for early clinical intervention while managing AIS, and further research should explore serum CIRP levels as prognostic indicators in AIS.
Source: Frontiers in Neurology - July 14, 2023 Category: Neurology Source Type: research
Influence of motivation on rehabilitation outcomes after subacute stroke in convalescent rehabilitation wards
ConclusionMotivation might not directly affect rehabilitation outcomes assessed by the functional independence measure. Furthermore, many participants remained highly motivated, although their motivation decreased at one or three months after admission.Clinical rehabilitation impactAssumptions that rehabilitation is ineffective because of low motivation may not be correct. To examine the influence on outcomes, both motivation and daily activities should be considered.
Source: Frontiers in Neurology - July 14, 2023 Category: Neurology Source Type: research
Lifelong cerebrovascular disease burden among CADASIL patients: analysis from a global health research network
DiscussionEarly screening and targeted treatment strategies are warranted to help CADASIL patients with symptom management and risk mitigation.
Source: Frontiers in Neurology - July 14, 2023 Category: Neurology Source Type: research
Association of lactate-to-albumin ratio with in-hospital and intensive care unit mortality in patients with intracerebral hemorrhage
ConclusionOur study suggests that a high LAR is associated with an increased risk of in-hospital and ICU mortality in patients with ICH. Thus, the LAR is a useful prognostic predictor of clinical outcomes in patients with ICH.
Source: Frontiers in Neurology - July 13, 2023 Category: Neurology Source Type: research
Case report: “Proust phenomenon” after right posterior cerebral artery occlusion
In this study, we provide the inaugural description of aversive odor-evoked autobiographical memories after stroke in the right hippocampal, parahippocampal, and thalamic nuclei. As potential underlying neural signatures of the phenomenon, we discuss the disinhibition of limbic circuits and impaired communication between the major networks, such as saliency, central executive, and default mode network.
Source: Frontiers in Neurology - July 13, 2023 Category: Neurology Source Type: research
Predictors of favorable outcome and mortality after endovascular thrombectomy in young Chinese patients with large vascular occlusions
ConclusionThis study demonstrate that EVT provides higher rates of arterial recanalization, rather than better favorable outcomes and lower risk of death at 3 months in young Chinese patients with AIS-LVO. Increased NIHSS scores on admission may be associated with poor patient prognosis.
Source: Frontiers in Neurology - July 12, 2023 Category: Neurology Source Type: research
Top-down and bottom-up stimulation techniques combined with action observation treatment in stroke rehabilitation: a perspective
Stroke is a central nervous system disease that causes structural lesions and functional impairments of the brain, resulting in varying types, and degrees of dysfunction. The bimodal balance-recovery model (interhemispheric competition model and vicariation model) has been proposed as the mechanism of functional recovery after a stroke. We analyzed how combinations of motor observation treatment approaches, transcranial electrical (TES) or magnetic (TMS) stimulation and peripheral electrical (PES) or magnetic (PMS) stimulation techniques can be taken as accessorial physical therapy methods on symptom reduction of stroke pa...
Source: Frontiers in Neurology - July 11, 2023 Category: Neurology Source Type: research
Editorial: Quality of stroke care: what could be improved, and how?
Source: Frontiers in Neurology - July 11, 2023 Category: Neurology Source Type: research
Improving door-to-reperfusion time in acute ischemic stroke during the COVID-19 pandemic: experience from a public comprehensive stroke center in Brazil
ConclusionAcute stroke care continued to be a priority despite the COVID-19 pandemic. The implementation of a thrombolytic bolus and the start of continuous infusion on the CT scan table was the main factor that contributed to the reduction of DNT. Continuous monitoring of service times is essential for improving the quality of the stroke center and achieving better functional outcomes for patients.
Source: Frontiers in Neurology - July 10, 2023 Category: Neurology Source Type: research
Rasch validation of a new scale to measure dependency in arm use in daily life: the Upper Limb Lucerne ICF-based Multidisciplinary Observation Scale
DiscussionThe new Rasch-based UL-LIMOS is a valid ICF-based observation performance scale at the ICF-activity level, to evaluate dependency during upper limb use in daily life in adults with stroke. Additional psychometric analyses are warranted. The UL-LIMOS would be a valuable addition to the core assessments of adults with (sub) acute stroke.
Source: Frontiers in Neurology - July 10, 2023 Category: Neurology Source Type: research
