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Source: Frontiers in Neurology
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Total 2557 results found since Jan 2013.
Can we trust computers to assess the cognition of stroke patients? A systematic review
ConclusionsAlthough the use of CCA tools for assessing the cognition of post-stroke patients is becoming popular, there are still some limitations and challenges of using such tools in stroke survivors. More evidence is thus needed to verify the value and specific role of these tools in assessing the cognitive impairment of stroke patients.
Source: Frontiers in Neurology - May 25, 2023 Category: Neurology Source Type: research
Rehabilitation: a key service, yet highly underused, in the management of young patients with sickle cell disease after stroke in DR of Congo
Source: Frontiers in Neurology - May 24, 2023 Category: Neurology Source Type: research
Variants in genes related to inflammation and endothelial function can increase the risk for carotid atherosclerosis in southwestern China
ConclusionThe prevalence of carotid atherosclerosis was observed to be extremely high in the high-risk stroke population in southwestern China. There were associations observed between the specific variants in inflammation and endothelial function relevant genes and carotid atherosclerosis. The high-risk interactive genotypes among IL1A rs1609682, ITGA2 rs1991013, and HABP2 rs7923349 significantly increased the risk of carotid atherosclerosis. These results are expected to provide novel strategies for the prevention of carotid atherosclerosis. The gene–gene interactive analysis used in this study may be very helpful to e...
Source: Frontiers in Neurology - May 24, 2023 Category: Neurology Source Type: research
Relationship between serum bicarbonate levels and the risk of death within 30 days in ICU patients with acute ischemic stroke
ConclusionLow baseline bicarbonate levels and decreased bicarbonate levels during the ICU stay were associated with a high risk of 30-day mortality in acute ischemic stroke patients. Special interventions should be offered to those with low baseline and decreased bicarbonate levels during their ICU stay.
Source: Frontiers in Neurology - May 24, 2023 Category: Neurology Source Type: research
Stroke burden and attributable risk factors in China, 1990 –2019
ConclusionThis study reinforced the findings of an increased stroke burden in China. Precise stroke prevention strategies are needed to reduce the disease burden of stroke.
Source: Frontiers in Neurology - May 24, 2023 Category: Neurology Source Type: research
“Time lost is clot resolution lost”: the neglected perspective of the therapeutic time window for ischemic stroke
Source: Frontiers in Neurology - May 24, 2023 Category: Neurology Source Type: research
Altered flexor carpi radialis motor axon excitability properties after cerebrovascular stroke
ConclusionIn contrast to our expectations, FCR axons were not hyperexcitable after stroke. Rather, FCR axons were found to be hyperpolarized bilaterally post stroke, and this was associated with disability and [K+]. Reduced FCR axon excitability may represent a kind of bilateral trans-synaptic homeostatic mechanism that acts to minimize motoneuron hyperexcitability.
Source: Frontiers in Neurology - May 22, 2023 Category: Neurology Source Type: research
Early post-stroke cognitive impairment and in-hospital predicting factors among stroke survivors in Ethiopia
ConclusionNearly one-third of stroke survivors developed PSCI. Moreover, further research is needed with a larger sample size, showing a time trend and longer follow-up duration.
Source: Frontiers in Neurology - May 22, 2023 Category: Neurology Source Type: research
Effects of low-frequency rTMS combined with antidepressants on depression in patients with post-stroke depression: a systematic review and meta-analysis
ConclusionThe results of this meta-analysis evidenced the efficacy and safety of low-rTMS combined with antidepressants in the treatment of depression in PSD patients. The combined therapy could reduce The depression state and the levels of IL-6 and TNF-α, and enhance the cognitive function of patients. In addition, low-rTMS had fewer adverse effects, proving safety. However, there are shortcomings, such as a lack of long-term follow-up, different intervention sites of low-rTMS, and different intervention frequencies (0.5 or 1 Hz). Thus, in the future, RCTs with a larger sample size and longer-term observation are require...
Source: Frontiers in Neurology - May 19, 2023 Category: Neurology Source Type: research
Progress in the clinical application of constraint-induced therapy following stroke since 2014
Stroke is a group of cerebrovascular diseases with high prevalence and mortality rate. Stroke can induce many impairments, including motor and cognitive dysfunction, aphasia/dysarthria, dysphagia, and mood disorders, which may reduce the quality of life among the patients. Constraint-induced therapy has been proven to be an effective treatment method for stroke rehabilitation. It has been widely used in the recovery of limb motor dysfunction, aphasia, and other impairment like unilateral neglect after stroke. In recent years, constraint-induced therapy can also combine with telehealth and home rehabilitation. In addition, ...
Source: Frontiers in Neurology - May 19, 2023 Category: Neurology Source Type: research
Stress hyperglycemia as a modifiable predictor of futile recanalization in patients undergoing mechanical thrombectomy for acute ischemic stroke
DiscussionFR is common after MT. We recognized older age, female sex and baseline NIHSS as non-modifiable predictors of FR. On the other hand, time from symptoms onset to MT and stress hyperglycemia were modifiable pre- and post-MT factors, respectively. Any effort should be encouraged to reduce the impact of these modifiable predictors.
Source: Frontiers in Neurology - May 19, 2023 Category: Neurology Source Type: research
Association of LIPC polymorphisms with stroke risk in the Chinese population
ConclusionThis study indicated that rs690 and rs6074 in LIPC were significantly associated with increased risk of stroke in the Chinese population, possibly by regulating the levels of PDW, HCT, and LDL-C.
Source: Frontiers in Neurology - May 18, 2023 Category: Neurology Source Type: research
Case report: Young-onset large vessel ischemic stroke due to hyperhomocysteinemia associated with the C677T polymorphism on 5,10-methylenetetrahydrofolate reductase and multi-vitamin deficiency
Hyperhomocysteinemia is an important risk factor for cerebral infarction. Herein, we report on a 30-year-old man previously diagnosed with epilepsy who presented with right hemiplegia and total aphasia. Magnetic resonance imaging showed a fronto-temporal ischemic lesion due to occlusion of the left middle cerebral artery. Clinical testing and imaging demonstrated that he had hyperhomocysteinemia induced by multiple factors including the C677T polymorphism on 5.10-methylenetetrahydrofolate reductase (MTHFR), and multiple vitamin deficiencies. The C677T polymorphism on MTHFR is closely related to hyperhomocysteinemia and fol...
Source: Frontiers in Neurology - May 18, 2023 Category: Neurology Source Type: research
Association between hysterectomy status and stroke risk and cause-specific and all-cause mortality: evidence from the 2005 –2018 National Health and Nutrition Examination Survey
ConclusionOur study found a significant association between hysterectomy and stroke, even after adjusting for other factors that could impact risk, such as the American Heart Association (AHA)'s Life's Simple 7 cardiovascular health score and variables of age, ethnicity, marital status, income, education, and depression severity.
Source: Frontiers in Neurology - May 18, 2023 Category: Neurology Source Type: research
Neurosyphilis with positive anti-N-methyl-D-aspartate receptor antibody: a case report
A case of neurosyphilis with a positive anti-N-methyl-D-aspartate receptor (NMDAR) antibody was reported. A 54-year-old man who presented with acute memory deficits was admitted to our hospital. Acute ischemic stroke (AIS) was initially considered, and he was prescribed intravenous thrombolysis with recombinant tissue-type plasminogen activator (rt-PA). However, the intermittent onset of episodic memory and orientation disorder still occurred. No diffusion restriction was indicated by magnetic resonance imaging (MRI), and subclinical seizures were frequently found by electroencephalogram (EEG). Rapid plasma reagin (RPR) te...
Source: Frontiers in Neurology - May 18, 2023 Category: Neurology Source Type: research
